增强子

EB病毒特异性增强子CAT报告质粒构建策略

Construction strategy of CAT reporter plasmids with Epstein-Barr virus specificity enhancer

CAAT/增强子结合蛋白在IL-6调节血管紧张素原基因表达中的作用

Role of caat / enhancer binding protein in IL 6 regulation of angiotensinogen gene expression

HBV基因组上有二个增强子序列。

There are two enhancers in HBV genome .

探讨人的增强子结合蛋白（C／EBP）相关基因。

Objective To explore the human C / EBP related genes .

P53与乙型肝炎病毒增强子Ⅰ上游P53样应答元件结合序列关系研究

Interaction of p53 with p53 Response Element Like Binding Sequence at Upstream of Hepatitis B Virus Enhancer ⅰ

异种移植转基因用含杂合增强子UI的人衰变加速因子重组基因的构建

Construction of recombinant human decay accelerating factor gene using UI enhancer for high-performance expression in xenotransplantation

结果PCR扩增所得AFP增强子片段的长度和序列通过琼脂糖凝胶电泳、DNA测序得到证实。

Results : The length and sequence of AFP enhancer amplified by PCR were confirmed by agarose gel electrophoresis and DNA sequencing .

Nodal基因的第一内含子中存在着顺式调控增强子元件

A Cis - regulatory Enhancer Element of the nodal Gene is Present in Its First Intron

应用酵母单杂交体系筛选与大鼠谷胱甘肽S-转移酶P增强子GPEⅠ相互作用的转录激活因子

Screening the trans-action Factors Binding to the Enhancer Element of Rat GST-P by Yeast One hybrid System

结论X基因区及重叠核心启动子区、增强子Ⅱ区多位点变异可能是HBV隐匿性感染的分子基础。

Conclusion Mutations of HBV in X gene and the overlapping core promoter , enhancer ⅱ may be the molecule bases of HBV occult infection .

HBV是嗜肝病毒，实验证明HBV基因组的两个区域具有转录增强子活性，并且具有明显的肝特异性以及协同作用。

Many researches have reported that two domains in the HBV genome had enhancer activity and both enhancers had liver-specific activity and synergistic action .

CCAAT/增强子结合蛋白α对K562细胞分化和凋亡的影响及其机制

Effect of enhancer-binding protein C / EBP α on differentiation and apoptosis of K562 cells and its possible mechanism

插入增强子后人β－珠蛋白基因在MEL细胞中的表达

Retroviral-mediated Transfer of Human β - globin Gene and Its Enhancer into MEL Cells

真核基因转录激活调控是在启动子、增强子等顺式调控元件和转录因子、激活因子以及RNA聚合酶II（PolII）等调控蛋白的参与下协同进行的。

The eukaryotic gene transcriptional activation by RNA polymerase II ( RNA pol II ) requires interaction between cis-acting regulatory elements and trans-acting factors .

用报告基因的检测方法，发现这332bp区域作为增强子，负责响应LPS的刺激。

Using the reporter assay system , we identified the 332 bp region as an enhancer to be responsible for LPS stimulation .

小片段红系特异增强子对MEL细胞中外源β珠蛋白基因表达调控的作用

Small Erythroid Enhancer Fragment on the Expression of Transferred β - globin Gene in MEL Cells

携带AFP增强子反义c-fms真核表达载体的构建及其临床意义

Construction of c-fms antisense eukaryotic expressing vector bearing AFP enhancer and its clinical significance

结果：发现受白蛋白增强子／启动子转录调控的IL－2和TNF基因在原位感染实验性肝癌可使肝癌逐渐缩小。

Results : It was found that the hepatoma regressed gradually following in situ transfer with IL-2 and TNF genes under transcriptional control of albumin enhancer / promoter .

目的：构建含杂合增强子UI的人衰变加速因子（DAF）重组基因的表达载体，应用于转基因动物克服异种器官移植排斥反应的研究。

Objective : To construct the recombinant human decay accelerating factor gene using UI enhancer for high-performance expression in xenotransplantation .

这两个序列中含有多个复制转录因子的结合位点、增强子基序、多个完全的和非完全的反向重复序列以及潜在的DNA弯曲核心序列样结构。

Both the MAR loci show numerous replication / transcription factor binding sites , enhancer motifs , several perfect or imperfect inverted repeats , and sequences sharing the common features of the potential DNA bending core sequence .

4×35s增强子的克隆及其功能验证

Cloning of 4 × 35s enhancers and its function verification

目的：克隆纤维连结蛋白（FN）启动子和检测其转录活性，并初步研究增加SV40增强子对其转录活性的影响。

AIM : To clone fibronectin ( FN ) promoter and identify its transcriptional activity combined with SV40 enhancer .

Nestin基因的第二内含子具有中枢神经系统（centralnervoussystem，CNS）组织特异性增强子活性，然而负责调控该基因在神经发育过程中表达的转录因子尚不明确。

The second intron of nestin gene possesses the central nervous system ( CNS ) specific enhancer . However , the molecular mechanism of expressional regulation of nestin gene in the neural development remained unclear .

目的通过筛选乙型肝炎病毒（HBV）增强子Ⅰ（Enhl）结合蛋白，为HBV复制机制的研究探索新的途径。

Objective To screen the hepatitis B virus ( HBV ) enhancer ⅰ DNA-binding proteins , and to investigate their potential role in the regulation of replication and expression of HBV DNA .

HP8：增强子结合蛋白家族的一个新基因的cDNA克隆

HP8 : The cDNA clone of a novel member of C / EBP gene family

S基因区未发现有义突变，X基因区及重叠核心启动子区、增强子Ⅱ区发现多位点变异，可能与HBV隐匿性感染有关。

Sequencing of the amplified fragments showed mutations in the region of X gene and the overlapping core promoter , enhancer ⅱ . No significant mutations were founded in the region of s gene .

目的根据翻译起始调控的定量理论及利用翻译增强子序列，提高人干扰素α1型变种IFNα1C基因的原核表达。

Objective To increase prokaryotic expression level of IFN α 1C gene through the quantitative theory of translational control and the translational enhancer sequence .

对9120株独立增强子捕获标签系的T1代未成熟种子进行了GUS染色分析，观察并统计了胚，胚乳和种皮中GUS基因的表达频率。

Immature T_1 seeds of 9,120 independent enhancer trap lines were collected for GUS expression pattern analysis on embryo , endosperm and seed capsule .

c-fms癌基因异常激活机制及携带AFP增强子反义c-fms与肝癌的研究

The study of abnormal activating mechanism of c-fms oncogene and antisense c-fms bearing AFP enhancer with hepatocellular carcinoma

U3重复区序列表现出增强子的活性。

The U3 repeat box acted as an enhancer ;