棉酚

用高效液相色谱法（HPLC）测定棉籽蛋白中的游离和总棉酚

Determination of free and total gossypol in cottonseed protein by HPLC

停服棉酚后恢复的大鼠精母细胞DNA合成的研究

A study of DNA synthesis of the repopulating spermatocytes in the rats after withdrawal of gossypol treatment

HPLC法测定棉籽饼粕饲料中的游离棉酚

Determination of free gossypol in cottonseed cake feed by HPLC

棉酚对大鼠~（42）K代谢影响的研究

A study of the effect of gossypol on the metabolism of ~ ( 42 ) k in rats

用放射自显影术观察棉酚对肾小管重吸收及转运~（42）K功能的影响

Autoradiographic observation of gossypol effect on reabsorption and excretion of ~ ( 42 ) KCl in the renal tubules

目前处于临床及临床前试验的Bcl-2抑制剂有10多种，棉酚就是一种处于临床Ⅱ期试验的Bcl-2天然抑制剂。

Gossypol , a natural inhibitor of Bcl-2 , is in phase ⅱ preclinical trials .

ATP酶。结果还表明棉酚有强烈的溶血作用，在低浓度时，棉酚能促使红细胞失钾。

At low concentrations , gossypol increased the loss of K + from erythrocytes .

排除棉酚等干扰提取棉纤维细胞RNA方法的研究

Isolation of High-quality RNA from Cotton Fiber Cells by Eliminating the Interference of Endogenous Phenolics and Secondary Metabolites

2，MTT法检测棉酚对睾丸间质细胞的增值的抑制作用。

Detect inhibition effect of Gossypol on Leydig cells in vitro using MTT methods . 3 .

棉酚对几种动物精子ATP酶抑制作用的比较研究

A comparative study on the inhibitory effect of gossypol on sperm ATPase in different animal species

醋酸棉酚对HeLa细胞作用的透射电镜和扫描电镜观察

Action of gossypol acetic acid on HeLa cells & sem and TEM observations

醋酸棉酚对白血病HL-60细胞凋亡及分化的影响

Effects of gossypol acetic acid on apoptosis and differentiation in leukemia HL-60 cells

紫外吸收光谱显示棉酚与DNA相互作用没有共价键形成.也不生成电荷迁移络台物。

The UV absorption spectrum shows that the interaction between gossypol and DNA does not result in the formation of a covalent bond or a charge transfer complex .

结果表明（1）棉酚对精于ATP酶的抑制作用是依赖浓度的变化；

The results showed that ( 1 ) the inhibitory action of gossypol on sperm ATPase is concentration-dependent ;

结果：总有效率醋酸棉酚组为87.18%，安宫黄体酮组为50%，两者差异显著（P＜0.01）。

The total effective rate of the former was 87.18 % , while the latter was 50 % . The significant difference was existed between two groups ( P < 0.01 ) .

醋酸棉酚对雄性木鼠睾酮、黄体生成素（LH）和卵泡刺激素（FSH）的影响

Effect of gossypol acetic acid on testosterone , LH and FSH levels of male rats

醋酸棉酚对大鼠睾丸HCG反应性及其受体功能的影响

Effect of gossypol acetate on the testicular hCG reactivity and it 's receptor in the rats

用放射免疫测定法研究性类固醇激素和棉酚对大白鼠垂体LH分泌的影响

The effects of sex steroid hormones and Gossypol on LH secretion of rat pituitary by radioimmunoassay

醋酸棉酚对雄性大鼠血清中睾酮、LH水平、激素活性及其受体的作用

Effect of gossypol on testosterone and LH in serum androgen activity and androgen receptor in rats

棉酚对SCE大鼠睾丸支持细胞的影响

Effect of gossypol on Sertoli cells in Sertoli cell-enriched ( sce ) rats

4醋酸棉酚能使促进凋亡基因Bax和P53的表达量升高，而使抑制凋亡基因Bcl-2的表达降低。

Gossypol acetic acid can promote the apoptotic gene Bax and P53 expression increased while inhibition of apoptosis gene Bcl-2 expression reduced .

棉酚联合放疗诱导宫颈癌HeLa细胞凋亡的研究

Study on the effect of gossypol combined with radiotherapy in inducing apoptosis of human cervical carcinoma HeLa cells

这表示棉酚很可能以共轭平面平行地插入到DNA分子双螺旋结构的碱基片层之间，与其中的胸腺嘧啶碱基以弱相互作用的极性键形成复合物。

It is probably that the conjugated plane of gossypol is inserted into the base pair pleated sheet of the DNA double helical structure to associate with thymine through weak polar bond .

醋酸棉酚对Raji细胞增殖和凋亡的影响

Effect of Gossypol Acetate on Proliferation and Apoptosis in Raji Lymphoblastoid Cell Line

各种动物精子ATP酶活力的下降情况显示，大鼠及家兔（哺乳动物）精子ATP酶对棉酚的敏感性比海胆（无脊椎动物）要高些。

And ( 2 ) it appears that the sperm ATP ase activity of mammalian species is more sensitive to gossypol than in invertebrate .

棉酚对海胆精子鞭毛轴丝及力蛋白（Dynein）ATP酶的抑制作用

The inhibitory effect of gossypol on the sperm flagella axonemal and dynein ATPase in sea urchin

喂服棉酚后的RPS，其精子特异蛋白BP和X1以及核心组蛋白H（2A）和H4有明显的减少。

In the RPS , the synthesis of sperm-specific proteins ( BP and X_1 ) and core histones ( H_ ( 2a ) and H_4 ) reduced markedly .

棉酚对罗非鱼（Oreochromisniloticus））离体精子毒性作用的研究

Effect of Gossypol on Survival of Spermatozoa of Tilapia Oreochromis niloticus in Vitro

当种子萌发48h以后，其子叶开始出现棉酚，但含量极低；

After 48 hours of germination , the cotyledons started to appear gossypol , although the gossypol contents were very low .

结果表明新的男性抗生育药物&棉酚似乎不影响垂体的LH分泌功能。

The data seem to indicate that this new antifertile agent for male , gossypol , does not influence the LH secretion of pituitary .