纺锤体蛋白
纺锤体蛋白
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它周期性地表达在细胞周期的G2/M期,并通过与细胞有丝分裂纺锤体微管蛋白结合,抑制半胱氨酸蛋白酶3、7(caspase3、7)的活性,从而抑制细胞凋亡。
It regularly expresses in G2 / M phase and suppresses the activity of caspase 3 and caspase ? by binding to the micro-tube protein of the cell mitotic spindle .
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Survivin的表达具有细胞周期依赖性,在细胞周期的G2/M期表达,在有丝分裂过程中与纺锤体的微管蛋白相连。
Survivin is expressed in the G2-M phase of the cell cycle in a cell cycle-regulated manner and associates with microtubules of the mitotic spindle .