TSAb

And it may be the molecular mechanism that TSAb induces thyroid cell proliferation .

这可能是TSAb引起甲状腺细胞增殖的分子机制。

TSAb had no effect on the expression of TTF-1 gene .

TSAb对TTF-1基因表达无明显影响。

Measurement of TSAb by using CHO cells that expressing human TSH receptor in Graves disease

用表达重组TSH受体的CHO细胞测定Graves'甲亢病人血清中的TSAb

The consistent rate of TSAb and TB ⅱ was 59.6 % in the cases .

TSAb和TBⅡ的一致率为59·6%。

The research into the receptor of TsAb

甲状腺刺激抗受体的研究

The Experimental Studies for Detection of Thyroid Stimulating Antibodies ( TSab ) in Sera of Patients with Graves ' Disease

Graves病患者血清中甲状腺刺激性抗体测定的实验研究

TSAb also could increase the expression of PAX-8 gene by the cAMP / PKA pathway in human thyroid cells .

TSAb也可使人甲状腺细胞中的PAX-8基因表达增加，其作用主要通过cAMP/PKA信号传导途径。

Objective : To study the antisenility effect of total glycosides extracted from acanthopanax bark ( TSAB ) .

目的：研究五加皮总苷（TSAB）的抗衰老作用。

Conclusion Orbital radiotherapy was an effective way to cure and prevent the progression of Graves ophthalmopathy . The effect of orbital radiotherapy may be related to the serum level of TSAb .

结论眼球后眶内软组织放疗能有效治疗浸润性突眼、明显改善眼部症状，TSAb水平与突眼的放疗效果呈负相关性，并可能成为预测放疗疗效的检测指标。

Objective To investigate the relationship of thyroid autoantibodies including serum thyroid stimulating antibody ( TSAb ), thyroid stimulation blocking antibody ( TSBAb ) and iodine intake with the development and prognosis of Graves ′ hyperthyroidism .

目的探讨血清甲状腺刺激性抗体（TSAb）、甲状腺刺激阻断性抗体（TSBAb）等甲状腺自身抗体、碘摄入量与Graves病（GD）甲状腺功能亢进症（甲亢）发病和转归的关系。

Results In the GO patients , serum thyroid stimulation antibody ( TSAb ) level was significantly lower after than before treatment by combined acupuncture and drug ( P < 0.05 ), but after the treatment , there was no significant difference between the groups .

结果针药结合治疗后GO患者血清甲状腺刺激性抗体（TSAb）水平较治疗前明显降低（P<0.05），但治疗后各组间未见明显差异。

TSAb was found in 21 of 23 patients with untreated Graves ' disease , in none of the patients with thyroid adenoma and controls , suggesting that cryopreserved human thyroid cells could be used in the study for the thyroid function and thyroid diseases .

这提示冻存一年内的人甲状腺细胞仍保持较好的活性与功能，可以作为甲状腺功能和甲状腺疾病基础与临床研究的材料。

Observations obtained from GD animal models raise the possibility that the heavily glycosylated A-subunit initiates or enhances immune responses to the TSHR that lead to hyperthyroidism and the TSHR N-terminal region is very important for recognition by TSAb .

对动物模型的研究证实，高度糖基化的TSHR的A亚单位启动或是增强了导致甲状腺功能亢进的免疫应答，TSHR氨基端在识别甲状腺刺激性抗体过程中具有重要作用。

These studies suggested : TSab existed in sera of most patients with GD , the changes cf TSab level were correlated with the clinical course of GD . The detection of TSab may be an useful parameter in monitoring clinical treatment of GD and predicting the GD recurrences .

作者认为：GD患者血清中存在TSab，其水平变化与临床疾病转归具有一定规律性，TSab检测对GD临床治疗监测、复发预测具有一定参考价值。