porin

Porin plays an important role in Neisseria gonorrhoeae survival and pathogenesis .

淋球菌孔蛋白对淋球菌的存活和致病起着重要作用。

Research of Multiple-antibiotic-resistance Negative Regulation Gene and Porin of Escherichia Coli

大肠杆菌多重耐药负性调节基因及膜孔蛋白的研究

The expression of porin protein were detected by SDS-PAGE .

利用SDS-PAGE测定淋球菌外膜孔蛋白的表达；

Immune response induced with the vaccine of porin of gonorrhoeae in animals

淋球菌孔蛋白疫苗在动物体内诱导的免疫应答

Results : There were 35 cases of type-A porin genotype and 46 cases of type B within the 71 cases .

结果：孔蛋白基因型为A型的有35例，其余46例为B型。

Expression of efflux pump protein and porin protein in multi-drug resistant strains of Neisseria gonorrhoeae

多重耐药淋病流行株孔蛋白和泵蛋白的表达

Construction of Neisseria gonorrhoeae Porin B Plasmid Recombinant and Its Expression in E.coli and Identification of Fusion Protein

淋病奈瑟菌孔蛋白B原核重组质粒的构建、表达与蛋白鉴定

Construction and Sequence Analysis of A Recombinant Plasmid Harbouring the Porin Gene PIA of Neisseria gonorrhoeae

淋球菌主要外膜蛋白PIA原核重组质粒的构建及序列分析

Objective : To construct an eukaryotic expression system carrying the Neisseria gonorrhoeae Porin IA ( PIA ) gene .

目的：构建淋病奈瑟菌孔蛋白PIA（PorinIA）基因的真核表达系统，为淋病DNA疫苗的研究提供材料。

This article also gives a presumption to T-DNA 's transport : The plant cell wall 's porin may be T-DNA 's natural channel .

对延宕至今的TDNA穿壁问题作了推测：植物细胞壁表面可能存有TDNA的天然穿壁孔道。

Conclusion A plasmid recombinant encoding porin B of Neisseria gonorrhoeae has been successfully constructed and expressed in E. coli .

结论淋病奈瑟菌孔蛋白PⅠB原核表达质粒构建正确。

Porin A-specific antibody avidity in patients who are convalescing from meningococcal B disease

B型脑脊髓膜炎患者恢复过程中的孔蛋白A特异性抗体亲和力

Porin is a transmembrane protein found in the outer membrane of mitochondria as well as in the outer membrane of gram positive bacteria .

孔蛋白是一种跨膜蛋白，主要存在于细菌质膜的外膜、线粒体和叶绿体的外膜上。

The deeper studies on the function of Porin would be of great importance in illuminating the mechanism of gonococcal pathogenesis and host anti-infection immunity .

深入研究孔蛋白的免疫功能，对阐明淋球菌的致病机制及宿主抗感染免疫机制具有重要意义。

Using carbapenem antibiotic can induce the deletion of out membrance porin gene , thus increasing MIC values of carbapenem antibiotic .

碳青霉烯类药物的使用可以诱导外膜孔道蛋白基因缺失，从而增加对碳青霉烯类抗菌药物的MIC值。

Study on Level of Delayed-type Hypersensitivity ( DTH ) and Transfered Protective rate of Immunized T Cell Induced by Porin of Salmonella Typhimurium in BALB / C Mice

鼠伤寒沙门氏菌porin诱导BALB/C小鼠迟发性变态反应和T淋巴细胞转移保护的研究

The protective rate of porin to the mice challenged with 500 LD50 murine Salmonella typhi was 70 % . The results showed good immunogenicity of STM-porin .

以500LD50鼠伤寒沙门氏菌攻击，其保护率为70%，提示STM－porin具有较强的免疫原性。

Since the Hp adhesin conservative region ( AB ) is outer membrane protein and porin type component , while these two kinds of protein are the excellent immunogen candidates of vaccination .

鉴于Hp已证实的四种粘附素保守区（AB）是外膜蛋白（OMP）和膜孔素（porin）样成分，而外膜蛋白和膜孔素样成分是优秀的疫苗候选抗原。

Objective To clone porin B ( P ⅰ B ) sequences of Neisseria gonorrhoeae and analyze the protein expression as basis of research in detection , prophylactic and therapeutic vaccine against the pathogen infection .

目的克隆和分析淋病奈瑟菌孔蛋白（porinⅠB，PⅠB）的基因序列并表达相应的蛋白质，为淋病奈瑟菌感染的检测和基因工程疫苗的研究与开发建立基础。

DTH was observed on the femoral leg of the rabbit administered intradermally with porin B.Slide agglutination reaction and bactericidal activity were measured by immunized rabbit serum in vitro .

后腿皮内注射孔蛋白B，观察迟发型超敏反应（DTH）、免疫血清体外玻片凝集及抗菌作用。

Objective Clone the genes of porin PIB and PIA of Gonococcus . To construct a recombinant eukaryotic expression vector containing both porin gene PIB and PIA , and to confirm the expression of pCI-PIB-PIA in muscule cells .

目的克隆淋球菌孔蛋白PIB和PIA基因并构建融合蛋白真核表达质粒pCI-PIB-PIA，了解pCI-PIB-PIA能否被小鼠骨骼肌细胞摄取并表达。

Methods : Porin B of gonorrhoeae expressed in E. coli by a recombinant plasmid and purified , were administered subcutaneously into the rabbit back . The serum antibody change and the highest titer of the rabbit was dynamically examined after immunized by ELISA .

方法：兔背皮下注射经原核构建表达并纯化的淋球菌孔蛋白B，ELISA动态检测免疫后大耳兔血清抗体滴度的变化及最高效价；

Results from the mutational analysis and qRT-PCR suggested that the EnvZ / OmpR system contributed to osmotic stress response of S. oneidensis and very likely engaged a similar strategy employed by E. coli , which involved reciprocal regulation of two porin coding genes .

突变分析和qRT-PCR结果表明，EnvZ/OmpR系统参与了S.oneidensis对渗透胁迫的反应，并很可能利用了与E.coli类似的策略，即对两个孔蛋白编码基因的表达进行反向调节。