sh2

Improving field seedling emergence of sh2 sweet corn by infusing via organic solvents

通过有机溶剂渗入提高超甜玉米种子田间出苗率

Experimental Study on SH2 Domain Containing Protein Tyrosine Phosphatase SHP-1 and SHP-2 in γ - ray Irradiation Induced Tumor

SHP-1和SHP-2在γ射线诱发的恶性肿瘤中作用的实验研究

SH2 domain can specifically recognize phosphated tyrosine residue , and mediate receptor tyrosine protein kinase signal transduction .

SHz结构域可以特异性识别磷酸化酪氨酸短序列，介导受体酪氨酸蛋白激酶信号转·2·导途径。

SH2 domain is extensively found in signaling molecules including protein tyrosine kinase , phosphatase , signaling adapter and transcription factor .

其对配体的识别特性取决于特定的空间结构。SH2结构域广泛存在于蛋白酪氨酸激酶、磷酸酶、磷酯酶、信号接头蛋白及转录因子等蛋白分子内，而参与调控相应的信号传导通路。

SH2 ( Src homology 2 ) domain was an important element in signal transduction and there were about 120 SH2 domains in human cells .

SH2（srchomology2）结构域是细胞信号转导中重要的元件之一，人SH2结构域共有约120种，对其进行研究将深刻揭示细胞信号转导的规律。

Objective : To investigate the expression of SH2 domain containing protein tyrosine phosphatase SHP-1 in thymus cells of γ - ray irradiation-induced leukemia mice .

目的：探讨蛋白酪氨酸磷酸酶SHP-1蛋白在γ射线体外诱发的白血病小鼠胸腺细胞中的变化特点。

SHP-2 , a cytoplasmic SH2 domain containing protein tyrosine phosphatase is involved in the signaling pathways of a variety of growth factors and cytokines .

SHP-2，一种含有SH2区域的胞浆蛋白酪氨酸磷酸酶，参与了各种生长因子和细胞因子的信号传导过程。

SHIP-1 is an SH2 domain containing inositol-5-phosphatase that appears to be a negative regulator of hematopoiesis .

SHIP-1是一个含有SH2结构域的肌醇5磷酸酶，在造血过程中起负调节作用。

OBJECTIVE To research the cloning and expression of SH2 ( src homology 2 ) domain and SHP2 ( SH2-protein tyrosine phosphatase ) .

目的研究SH2（Src同源体2）域和SHP2（含2个SH2域的蛋白酪氨酸磷酸酶）蛋白的基因克隆和表达。

The expression of Src homology 2 ( SH2 ) containing protein-tyrosine phosphatase 2 ( SHP-2 ) was assessed by immunoblotting .

用免疫印迹法检测含Src同源区2（SH2）蛋白酪氨酸磷酸酶2（SHP-2）的磷酸化水平。

Further CDD analysis showed that the SOCS-3 protein which deduced from the cloned sequence has the SH2 domain and the SOCS-box which are the basic domains of SOCS family .

进一步的结构域分析发现，推测的猪SOCS-3蛋白序列含有SOCS家族基本的SH2结构域和SOCS-box。

SHP-2 is a two SH2 domain-containing tyrosine phosphatase , widely expressed in various organizations involved in embryonic development , cell proliferation , differentiation , adhesion , migration and other biological behavior of the signal control .

SHP-2是一种含两个SH2结构域的酪氨酸磷酸酶，广泛表达于各组织，参与胚胎发育，细胞增殖、分化、粘附、迁移等多种生物学行为的信号调控。

All the members in Shc family have two functional domains : PTB domain and SH2 domain which can bind to phosphotyrosine and a central region ( denoted CH1 ) that contains critical tyrosine phosphorylation sites .

Shc家族都含有两种功能性结构域：能和磷酸化酪氨酸结合的PTB结构域和SH2结构域以及一个含有磷酸化酪氨酸的中央区域结构域CH1。

RT PCR showed that all samples expressed HCP gene , only one missense mutation at codon 225 ( AAC to AGC , Asn to Ser ) within N terminal SH2 domain was found in an ALL patient .

RTPCR显示所有标本中都有HCP基因表达，仅在1例急性淋巴细胞性白血病细胞中发现一错义突变，发生在HCP基因氨基末端的SH2结构域；

In an attempt to identify specific phosphotyrosine-containing proteins and potential tyrosine kinase pathways involved in anoikis resistance , a functional screening method based on the specific interaction between src homologue 2 ( SH2 ) domains and phosphotyrosine ( p-Tyr ) containing proteins was designed .

为此设计了一种基于SH2-PTyr特异性结合特性的功能性筛选方法，以期发现癌细胞失巢生存相关的酪氨酸磷酸化蛋白质，为最终明确酪氨酸激酶途径提供有力的实验依据。