丙泊酚

P组丙泊酚总量最高。

The total amount of propofol of group P is the most ;

芬太尼使所需丙泊酚靶控浓度下降（p＜0.05）。

Fentanyl decreased target propofol concentration significantly .

P组输注丙泊酚，按照预先设定的镇静水平调节输注速度；

Propofol was infused in group P , and the infusion velocity was adjusted to the desired sedation level .

丙泊酚对内毒素刺激小鼠腹腔巨噬细胞促炎细胞因子mRNA的影响

Effect of propofol on endotoxin-stimulated proinflammatory cytokine mRNA expression of murine celiac macrophages

丙泊酚预处理对大鼠离体心肌浅低温缺血/再灌注损伤后线粒体细胞色素C释放的影响

The effect of propofol preconditioning on cytochrome c release from mitochondria after mild hypothermic ischemia / reperfusion in isolated rat hearts

丙泊酚靶控输注在外科ICU病人清醒镇静中的应用

Application of target-controlled infusion with propofol for conscious sedation of SICU patients

丙泊酚的GC法测定

Determination of Propofol by GC

B组：待手术开始气腹稳定后，丙泊酚靶浓度降至2μg/ml并维持，通过调整雷米芬太尼的输注给药速度维持血流动力学稳定。

In group B , propofol target concentration was 2 μ g / ml after pneumoperitoneum , and remifentanil infusion rate was the same as that in group A.

丙泊酚诱导Fos蛋白与脑啡肽在大鼠脊髓共同表达

Co-expression of Fos-protein and enkephalin induced by propofol in rats spinal cord

方法：自愿接受者36例，采用单纯丙泊酚（1.0-1.5mg/kg）iv施行无痛胃镜检查。

METHODS : Intravenous propofol ( 1.0-1.5 mg / kg ) sedation was used in 36 volunteers during gastroscopy .

麻醉维持：R组瑞芬太尼每小时6~12μg/kg复合丙泊酚4~6mg/kg静脉持续输注。

The anesthesia was continued with a continuous infusion of remifentanil 6 ~ 12mg / kg per hour and propofol 4 ~ 6mg / kg in group R.

结论麻醉剂量的丙泊酚[4.0~6.0mg/（kg·h）]可以消除外显记忆和内隐记忆。

Conclusion Explicit memory and implicit memory appears to be impaired by propofol [ 4.0 ~ 6.0 mg / ( kg · h ) ] anesthesia .

丙泊酚靶控输注诱导时的EC（50）与听觉诱发电位指数的变化

EC_ ( 50 ) for propofol anesthesia using target-controlled infusion system and the changes in auditory evoked potential index

GABAA受体部分介导丙泊酚在中脑导水管周围灰质腹外侧区的致痛觉过敏作用

GABA_A receptor partially mediated propofol-induced hyperalgesia at ventrolateral periaqueductal gray ( vlPAG ) of rats

建立了丙泊酚脂肪乳的HPLC分析方法并进行了初步的质量研究。

HPLC analysis method for the propofol fat emulsion is established and a preliminary method on the quality of the emulsion is also conducted .

2丙泊酚静脉麻醉能增加患者血清SOD活性，降低MDA含量，具有显著的脑保护作用。

Propofol intravenous anesthesia can increase the serum SOD activity , reduce the content of MDA , has significant neuroprotective effect . 3 .

GABAA受体部分介导丙泊酚在大鼠脊髓水平的抗伤害作用

Partial mediation of GABA_A receptor in the antinociceptive stimulation of propofol at spinal level in rats

丙泊酚静脉输注对老年大鼠海马内M受体和NMDA受体的影响

Effect of intravenous propofol on muscarinic or NMDA receptor in the brain of aged rats

与麻醉前基础MAP相比，诱导及插管期E组MAP无显著变化（P>0.05），P组MAP在静注丙泊酚后明显降低，与基础MAP相比差异显著（P<0.05）。

MAP in E group had no significant difference compared with the base MAP . MAP was significantly decreased in group P after infusion of propofol ( P < 0.05 ) .

丙泊酚靶控输注（TCI）用于无痛拔牙的临床研究

Clinical study of target controlled infusion of propofol in pain-free exodontias

结论丙泊酚能通过降低IL-1β和IL-6水平，减少肝组织NO的产生，从而保护线粒体呼吸功能，改善细胞能量代谢。

Conclusion Propofol can protect the function of mitochondria through decreasing the level of IL-1 β, IL-6 and NO in septic mice .

目的比较瑞芬太尼（REM）复合丙泊酚在门诊肠镜中的临床应用。

Objective To compare the clinical application of compound fluid of Remifentanil ( REM ) and Propofol .

方法500例早孕要求人工流产孕妇随机分为A、B两组，A组用咪唑安定+芬太尼+丙泊酚，B组用芬太尼+丙泊酚行无痛人工流产术。

Methods : 500 pregnant patients required induced abortion were randomized into A group ( test group : midazolam + fentanyl + propofol ) and B group ( control group : fentanyl + propofol ) .

咪唑安定对丙泊酚TCI镇静催眠效应的影响

Effect of Midazolam on Sedation and Hypnosis of TCI Propofol

目的以脑电双频指数（BIS）为反馈控制变量，探讨丙泊酚闭环靶控输注复合舒芬太尼全凭静脉麻醉应用于颅脑手术的可行性。

Objective To investigate the feasibility of total intravenous general anesthesia via close-loop target-controlled infusion ( CLTCI ) in cerebral surgery .

方法用环己烷提取全血中的丙泊酚，以百里酚为内标定量，用HPLC荧光检测器测定丙泊酚含量。

Methods The propofol in blood was extracted with cyclohexane , and thymol was used as the internal standard , determining the concentration of propofol by HPLC fluorescence detector .

丙泊酚对大鼠空间学习、记忆及脑内nNOS表达的影响

Effects of Propofol on spatial learning , memory and nNOS expression in the brain of rats

控制性降压对切皮时丙泊酚EC50及术中相同BIS条件下靶控浓度的影响

The effect of controlled hypotension on EC50 of propofol for skin incision and intraoperative BIS value

目的：观察丙泊酚（P）、依托咪酯（E）和异氟烷（I）对胃癌根治术病人围术期血糖和胰岛素的影响。

Objective : To study the influence of propofol ( P ), etomidate ( E ) and isoflurane ( I ) on blood glucose and insulin levels in patients of stomach carcinoma during the radical operation .

方法选择49例ASAⅠ～Ⅱ级成年择期全麻手术病人，随机分为三组：丙泊酚组（Ⅰ组，18例）；

Methods 49 adult patients of ASA grade ⅰ ⅱ undergoing selective operation under general anesthesia were randomly divided into three groups .