全局调控

制约因素管理强调围绕系统目标的实现，抓住制约环节进行全局调控，不断实现整体持续优化。

MBC strives for an integrated predominance by focusing on the constraints so as to realize a global ongoing improvement and the system goals .

政府在循环经济中的作用是引导行为模式，规范企业运行、将循环经济全局调控。

The functions of government , in cyclic economy , should be to guide mode of conduct , regulate the operation of enterprises , profit coordination and NGO development , and achieve overall control over cyclic economy .

上述结果表明IrrE可能作为一个全局性调控蛋白增强E.coli的耐盐性。

Those results indicated IrrE may play a global regulator role in salt tolerance in E. coli .

美伐他汀生物合成基因簇已经被鉴定，受到途径特异性转录激活因子mlcR的正调控。但是，在桔青霉中，还没有发现控制美伐他汀生物合成的全局性调控因子。

Biosynthesis in P. citrinum has been identified . Among them , mlcR is a pathway-specific zinc cluster transcriptional activator of the mevastatin biosynthetic genes .

全局转录调控及其在代谢工程中的应用

Application of Global Transcription Machinery Engineering in Metabolic Engineering

总厂对实际生产情况缺乏全局性调控；

Lacks of overall control over real production condition ;

次生代谢产物的生物合成不仅受到途径特异转录因子的调控，还受到全局性调控因子的调控。

Biosynthesis of secondary metabolites not only regulated by way of specific transcription factor , it is also regulated by the global regulator .

CodY是多种革兰氏阳性菌一种重要的全局性转录调控因子，可调控大量毒力基因的表达，从而影响病原菌致病性。

CodY is an important global transcription regulator in most gram-positive bacteria , and regulates the expression of many virulence genes , thus affecting the pathogen pathogenicity .