凝血过程
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TM在抗凝血过程中发挥着重要作用。TM基因突变或表达减少能促使动脉血栓的形成;而局部TM基因过度表达能避免兔动脉血栓形成。
TM plays a key role in anticoagulation , and mutation or down-regulation of TM promotes while overexpression of TM prevents arterial thrombosis .
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并且,这两种凝血酶抑制方式在体内凝血过程中是分别独立进行的。当DS和HS同时存在时,两者起到协同增效作用。
The two ways of thrombin inhibition proceed independently in vivo , and there is synergism when DS and HS exist together .
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Xa因子是一种丝氨酸蛋白酶,在凝血过程中发挥关键作用。
Factor Xa ( Fxa ) is a trypsin-like serine protease and plays a pivotal role in the blood coagulation cascade .
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凝血酶(thrombin,Ⅱa)是一种生成于损伤处血管内皮细胞的多功能蛋白酶,它是参与凝血过程各个环节反应中的关键酶。
Thrombin is a multifunctional protease generated at sites of vascular injury . Thrombin is a critical enzyme in a variety of blood coagulation responses to vascular injury or wounding .
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诱发血液凝固机制是于血液中添加氯化钙溶液,其体积比为9:1。实验结果表明OCTSS和D1/e能够明确判别凝血过程的不同阶段。
Blood coagulation was induced by addition of 0.25M calcium chloride solution with volume ratio of 9: 1.Experimental results indicated that OCTSS and D1 / e could clearly distinguish different stages of coagulation process .
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电磁场变化率对血液粘度和凝血过程的影响
Change rate of electromagnetic fields improves blood viscosity and coagulation
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很多血栓防治药物研究从凝血过程入手。
Many drugs preventing and curing thrombus aim at coagulation .
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血液净化膜材在凝血过程中对凝血十二因子的接触活化
The Contact Activation of Factor XII During Plasma Incubation with Blood Purification Materials
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前者能催化凝血酶原转化为凝血酶,启动凝血过程。
The former can catalyze prothrombin into thrombin and activate the clotting process .
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血液净化膜材和抗凝剂对凝血过程中接触活化的影响
Effect of Blood Purification Materials and Anticoagulants on the Contact Activity of Factor ⅹⅱ
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凝血过程在血栓形成中发挥着极为重要的作用。
Coagulation has great influence to thrombosis .
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目的建立反映两阶段凝血过程的筛选试验。
Objective To establish a screening test that can reflect two stages of coagulation process .
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因此,其作用机制可能是影响了凝血过程的某些环节。
Therefore , the mechanism may lie in its influence on some links in coagulation process .
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仪器定量检测凝血过程,并打印凝血曲线。
The instrument can be used to automatically detect the process of blood coagulation and print coagulation curves .
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许多研究表明,凝血过程在动脉血栓性疾病中起重要作用。
Many studies showed that the blood coagulation process plays an important role in the evolution of acute arterial thrombotic events .
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凝血酶是参与凝血过程中瀑布反应的关键酶,也是一种多功能的丝氨酸蛋白酶。
Thrombin , a key enzyme in the waterfall reaction of blood clotting , is also known as the multifunction serine protease enzyme in other field .
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结论:组织因子途径抑制物作为组织因子途径凝血过程的抑制物,间接反应了不稳定心绞痛发作过程中血管内皮的损伤和凝血状态。
CONCLUSION : TFPI acted as an inhibitor of tissue factor pathway reflected the vascular endothelial injury and the states of coagulation indirectly in unstable angina progression .
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用此装置检测了鸡、兔、大鼠、及人的离体血液凝血过程中有物理性质改变的粘度指标,随时间变化的动态曲线及特征参数,表明此法可行、有效。
The changing rules of viscosity related to time and the parameters that influenced the blood coagulation in plasma samples of chicken , rabbit , rat and human were measured .
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血栓弹力图是动态凝血过程中切应力大小随时间变化的描记,也是复弹性模量大小的直接反映。
The Thrombelastograph ( TEG ) is the continuous recording of the stress during dynamic process of blood coagulation and also reflects the variation of the absolute value of complex elasticity modulus .
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凝血酶和血小板作为参与凝血过程的重要因子是多种抗凝药物作用的靶点,同时越来越多的研究表明在动脉粥样硬化发生发展过程中血管损伤处聚集的凝血酶,血小板对血管壁炎症反应具有重要促进作用。
Thrombin and platelet as the targeting sites for many anti-coagulant drugs were the important factors involved in blood coagulation , while more and more researches indicated that thrombin and platelet accumulated at damaged site of vessel played an important promoting role for the inflammatory response of vessel wall .
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维生素K在合成凝血胶原过程中是必需的,因此在维生素K的吸收发生障碍的情况下,凝血胶原的产生就会减缓,并导致流血时间的延长。
Vitamin K is needed to synthesize prothrombin , so conditions that impair the vitamin 's absorption result in prothrombin deficiency and a tendency to prolonged bleeding .
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目的检测正常足月妊娠胎盘、蜕膜和子宫肌层中是否富含在启动凝血、止血过程中起关键作用的组织因子(TissueFactor,TF),初步探讨TF与产科凝血间的关系。
Objective To explore the relationship between obstetrical coagulation and tissue factor ( TF ), the key component of the initiation of coagulation .
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它不仅在抗凝血因子形成过程中起着保护屏障作用,而且其自身可分泌因子调节血管管腔和保持内环境稳态的作用。
It not only plays a protective function in the formation of anti-coagulation factor , but also it can secret some cellular factor to regulate blood vessel lumen and maintain internal environment .
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结论固肾止漏胶囊能通过内源性和外源性2种凝血途径调节凝血过程,促进止血和凝血,并有抗炎及散瘀作用。
Its mechanism may be related to the increase of coagulation through the intrinsic and extrinsic coagulation Pathway , removing blood stasis and anti-inflammatory effect .
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患者纤维蛋白原、抗凝血酶Ⅲ及纤维蛋白降解产物明显增高,提示凝血和抗凝血过程均增强;
Activities of antithrombin ⅲ( AT - ⅲ), quantities of fibrinogen and fibrin degradation Products ( FDP ) increased significantly , which revealed that both the activities of coagulation and anti-coagulation increased .
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为了检测鱼类的血液被稀释后凝固加快的酶促反应机理,本试验参照哺乳动物的凝血反应的基本过程,对鱼的凝血反应进行了分步检测。
To determin the diluted blood clotting of fish speed up the enzymatic reaction mechanism , we refer to the basic process of blood clotting response of mammals , fish test carried out step by step .
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凝血因子X(FX)在凝血过程中起重要的作用。
Coagulation Factor X ( FX ) is a plasma protein which plays an important role in blood coagulation .
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人凝血因子Ⅶ在肝脏内合成,是一种参与凝血过程的重要单链糖蛋白。
Human coagulation factor ⅶ is a single-chain glycoprotein synthesis in a liver .
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人凝血因子Ⅶ(FⅦ)是一种维生素K依赖的单链糖蛋白,在体内凝血过程中发挥着重要的作用。
Human blood coagulation factor ⅶ( F ⅶ) is a vitamin K-dependent , single-chain glycoprotein that participates in the extrinsic phase of blood coagulation .
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分泌入血的凝血因子,一旦被激活,将参与凝血级联,触发一系列酶促反应,最后纤维蛋白原变为纤维蛋白,完成凝血过程。
After secretion into the blood , these four vitamin K-dependent proteins from part of the coaguLation ( fibrin ) through a series of enzymatic actions , and last the cruor process has been fulfilled .