单纯病例研究

基于相乘模型交互作用的叉生分析OR值为1.35（P0.05），其结果与分层分析和单纯病例研究一致；

The result of interaction based on multiplicative model was 1.35 ( P 0.05 ), compatible with that of stratified analysis and case only study .

方法分别导出了logistic模型、对数线性模型在传统病例对照研究、单纯病例研究、不完全病例对照研究中主效应以及基因与环境交互作用效应的极大似然估计，并通过实例分析其应用价值。

Methods The effects of logistic model and log-linear model for estimating the main effects and gene-environment interaction effect were estimated by means of maximum likelihood methods in traditional case-control studies , case-only studies and partial case-control studies , respectively . An example was also illustrated .

方法以口服避孕药和Leiden因子Ⅴ基因突变与静脉血栓栓塞的病例对照研究为例，分析2×4叉生分析表核心信息，并与分层分析、单纯病例研究相比较。

Methods Through elaboration of a case-control study on the increased risk of venous thrombosis in oral-conceptive users who were carriers of factor ⅴ Leiden mutation , core information from 2 × 4 crossover table were analyzed and compared with stratified analysis and ' case only ' study .

时间序列方法与单纯病例研究法的表现略佳。

Poisson regression and case-only approach provide better statistical performances .

寻常型银屑病单纯病例研究

Case-merely Study on Psoriasis Vulgaris

单纯病例研究

Case - only study

本文就单纯病例研究的设计、统计分析方法及应用作了简要介绍。

This paper presents a general framework for the design , statistical analysis and applications of such case-only design .