单胺类神经递质
- monoamine neurotransmitter
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5-羟色胺(5-hydroxytryptamine,5-HT)是一种重要的单胺类神经递质,其功能异常可能与包括阿尔茨海默病(alzheimerdisease,AD)在内的神经系统疾病密切相关。
5-hydroxytryptamine ( 5-HT ) is an important monoamine neurotransmitter , whose abnormal function may closely correlate with nervous system diseases including Alzheimer disease ( AD ) .
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采用Morris水迷宫检测各组小鼠的学习记忆能力、高效液相色谱-电化学法检测各组小鼠脑单胺类神经递质的含量。
The learning and memory ability of mice were detected with Morris water maze and the monoamine neurotransmitter contents in brain were detected with HPLC-ECD .
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不同剂量维生素E对慢性间断性缺氧大鼠记忆能力及脑内单胺类神经递质的影响
Effect of Vitamin E on Memory and Brain Monoaminergic Neurotransmitter in Chronic Episodic Hypoxia Rat
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老年性痴呆患者事件相关电位P(300)及单胺类神经递质的关系
A study on relation with event-ralted potential P_ ( 300 ) and the serum levels of monoamine neurotransmitter with senile dementia patients
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健脑益智冲剂对多发梗塞性痴呆大鼠模型大脑皮层单胺类神经递质和P物质含量的影响
Effects of Jian Nao Yi Zhi Instant Granules on Contents of Monoamine Neurotransmitters and Substance P of Cerebral Cortex in Rats of Multi-Infarct Dementia
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荧光法测定SD大白鼠不同脑区的单胺类神经递质
Determination of the Content of Monoaminergic Transmitters in SD Rat Brain by Fluorometry
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比较不同临床类型强迫症之间CSF和血浆单胺类神经递质的含量,探讨不同的强迫症状与单胺类神经递质的关系。
To compare CSF and plasma levels of monoamine neurotransmitters among different clinical types of OCD .
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骨髓基质细胞对离体Parkinson鼠脑片单胺类神经递质的影响
Influences on the monoamine neurotransmitters by co-culturing bone marrow stromal cells onto brain slice of parkinson ' rat
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脑梗死后遗症大鼠模型脑组织ATP、ADP及单胺类神经递质含量的变化
Changes of ATP , ADP and monoamine neurotransmitters in brain of rat models of cerebral infarction sequela
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给予胰岛素治疗后,6h组单胺类神经递质含量也显著上升,但明显低于同时间的缺血组,伤后*开始回落,3d、sd已接近对照组。
In insulin treated group , the transmitters begin to rise 6 hours postischemia , but they are lower than that in ischemic group .
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用高效液相加电化学法检测大鼠不同脑组织中单胺类神经递质的含量;用酶联免疫吸附法检测大鼠血清中IL-1β、IL-2的含量。
Examining the content of the monoamine neurotransmitters in different brain tissues of the rats were measured by electrochemical and high pressure liquid chromatography methods .
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为研究饮食性肥胖鼠下丘脑单胺类神经递质含量和肥胖的关系,以及耐力训练对其影响,选用44只雄性离乳SD大鼠,36只饲以高脂饲料,其余为对照。
This study was to clarify the relationship of hypothalamus monoamine neurotransmitters and obesity , and the effects of endurance . training on them in dietary obese rats .
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结论:单胺类神经递质代谢异常可能是导致ADHD患儿注意力不能集中、活动过度、学习困难的原因之一。
Conclusion : Abnormity of catecholaminergic neurotransmitters metabolism might lead to scatterbrain , hyperactivity , and difficult studying in patients with ADHD .
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益胃法对初老雌性大鼠CFS模型中枢单胺类神经递质代谢影响的实验研究
Study on the Influence of " Yiweifa " to the Metabolism of Central Monoamine Neurotransmitter of the Primary Senile CFS Rat
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观察各组大鼠一般情况、阴道脱落细胞,并用荧光分光光度法检测大鼠中枢单胺类神经递质NE、DA、5-HT的含量。
The general conditions , vaginal exfoliate cell were observed , the contents of neurotransmitter NE ? DA and 5-HT in brain stem were detected by fluorospectrophotometry .
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目的观察耗竭单胺类神经递质对缺血性纹状体、海马和皮质神经元CaMPKⅡ活性的影响。
Objective To observe the influence of depletion of monoamines on the CaM PK ⅱ activity in the striatum , hippocampus and cerebral cortex of ischemic gerbils .
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本文将高效液相色谱(HPLC)技术及将其与微透析技术结合,建立大、小鼠氨基酸和单胺类神经递质的检测方法并应用于抗脑缺血药物的药理药效研究。
In this paper , HPLC and microdialysis technique were combined to establish methods which can detect these neurotransmitters . Moreover , the methods were employed to study the effects and mechanisms of anti-ischemia medicine .
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HPLC-ECD法对精神分裂症患者脑脊液单胺类神经递质的检测
HPLC-ECD method for the determination of CSF level of monoamine neurotransmitter in patients with schizophrenia
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方法:采用线栓法制备局灶性脑缺血大鼠模型,并结合孤养、束缚应激制成PSD大鼠模型,观察大鼠糖水消耗试验,自发性行为改变,下丘脑单胺类神经递质的变化。
Methods : A PSD rat model was set up on the base of focal cerebral ischemia by means of middle cerebral artery occlusion , followed by isolated feed and restraint stress .
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结论:PAF与单胺类神经递质共同参与缺血性脑损伤,并且银杏内酯B能特异性拮抗PAF受体及减少单胺递质的释放而具有抗脑缺血效应。
CONCLUSION : PAF and monoamine neurotransmitters may participate in the ischemic injury and ginkgolide B may possess cerebral protection against ischemic cerebral damage by inhibiting PAF receptor and decreasing the release of monoamine neurotransmitters .
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通过对强迫症治疗前后CSF和血浆中单胺类神经递质的含量变化比较,探讨氯丙咪嗪对强迫症单胺类神经递质的影响以及该药产生疗效的可能机制。
To explore the relationships between different obsessive-compulsive symptoms and monoamine neurotransmitters . 3 . To compare the changes of CSF and plasma monoamine neurotransmitters levels in patients with OCD before and after treatment .
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目的:观察银杏叶制剂(extractofGinkgobiloba,EGB)对实验大鼠脑缺血导致脑组织损伤后单胺类神经递质[去甲肾上腺素(NE)和多巴胺(DA)]含量的影响。
Objective To explore the effect of extract of Ginkgo Biloba ( EGB ) on monoamine neurotransmitter [ norepinephrine ( NE ) and dopamine ( DA ) ] levels in the brain tissue of cerebral ischemia rats .
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模型组大鼠出现脑内单胺类神经递质代谢紊乱:大脑皮层中NE含量增高,海马中NE、DA下降,下丘脑中5-HIAA下降。
Disorder of monoamine neurotransmitters in central nervous system such as NE , DA decrease in the cerebral cortex , 5-HIAA in the hypothalamus were detected in the CFS model rats and EA group .
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采用荧光分光光度法法测定慢性应激抑郁模型大鼠脑中去甲肾上腺素(NE)、多巴胺(DR)、5-羟色胺(5-HT)含量,发现药物对单胺类神经递质含量有显著性影响。
By method of fluorospectrophotometry , it manifests that the researched medicine can rise the level of the monoamines neurotransmitters such as 5-hydroxytryptamine , noradrenaline and dopamine in brains of the chronic unpredicted mild stress rats model obviously .
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目的:探讨中药复方右归饮对雄激素致不孕大鼠(ASR)血清性激素及下丘脑单胺类神经递质的影响。
Objective : To evaluate the effects of Yougui Yin ( YGY ) on serum sex hormones and monoamine neurotransmitter of hypothalamus in androgen - induced sterile rats ( ASR ) .
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以HPLC-EC法对照研究恶劣心境障碍大鼠额叶单胺类神经递质的改变。
HPLC-EC was used to study the changes of monoamine transmitters in frontal lobe of rat Dysthymic disorder Model .
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机械推拿可以调节慢性疲劳模型大鼠下丘脑和海马中单胺类神经递质的紊乱,调节单胺类神经递质的紊乱可能是机械推拿治疗CFS获效的机制之一。
Mechanical massage can regulate disorder in hypothalamic and hippocampal monoamine neurotransmitter concentrations in CFS model rats . Adjusting monoamine neurotransmitter concentrations can be one of the mechanisms through which mechanical massage can effectively treat CFS .
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目的:分析成人牙科畏惧症(DF)的流行病学特征及影响因素,并探讨单胺类神经递质与DF的关系。方法:本研究分为两部分。
Objectives : Investigate and analyze epidemiological characteristics and influencing factors of Dental Fear to adult patients , and address the relations between monoamine transmitters and adult Dental Fear . Methodologies : This research consists of two parts : 1 .
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结论TMS能够抑制大鼠缺血-再灌注损伤急性期单胺类神经递质的过量释放,从而减轻单胺类神经递质对神经细胞的毒性作用,保护脑组织。
Conclusion TMS may inhibit the excessive release of monoamine neurotransmitters in acute ischemia-reperfusion brain injury in rats , and thus decreases the toxic effect of monoamine neurotransmitters on neurons and protects brain tissues .
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目的:中枢内单胺类神经递质病变机制是经前期综合征(PMS)病因学研究的关键问题,也是推动PMS治疗学发展的关键所在。
Objective : The pathology mechanism of amino neurotransmitter in centrum is the key problem to the etiology of premenstrual syndrome ( PMS ), and is the key problem to develop the therapeutics of PMS too .