膜域

嗜麦芽黄单胞菌CG样受体跨膜域克隆与分析

Cloning and Analyzing of the Transmembrane Region of CG - like Receptor from X.Maltophilia

本试验通过用RT-PCR方法对5株不同亚型的禽流感病毒M2基因进行分析，预测其跨膜域二级结构，从而推测其功能的改变。

The M2 gene of 5 strains avian influenza virus isolated in Chinese were amplified by RT-PCR and analysed the sequence and predicted secondary structure of the transmembrane domain .

δ受体第4跨膜域中的丝氨酸（Ser177）被突变可使经典拮抗剂呈现激动剂的性质。

The mutation of a serine ( Ser 177 ) in transmembrane 4 of δ opioid receptor confers full agonistic properties to classical antagonists .

研究表明该基因序列编码的蛋白包含一个跨膜域、一个具有丝氨酸/苏氨酸激酶活性的胞内域和一个缺少N-末端信号肽的胞外域。

The deduced protein product of this gene contains a transmembrane region , an intracellular catalytic domain possessing serine / threonine kinase activity , and an extracellular domain which lacks the N-terminus signal peptide .

研究表明，异三聚体G蛋白与含有七次跨膜结构域的质膜受体密切偶联（GPCRs）。

Studies with mammalian cells established that heterotrimeric G proteins associated with plasma membrane receptors which contain 7 transmembrane domains ( GPCRs ) .

MPP穿膜结构域的结构模拟、特征分析及MPP介导的转基因载体体系的构建和转导研究

Structure Prediction and Analysis of the MPP PTD , Construction of MPP-mediated Gene Transferring Vector System and Transduction Study

研究结果提示，GnRH－R属于G蛋白偶联受体家族，由包含7次跨膜结构域的单一多肽链构成，编码327或328位氨基酸。

GnRH-R belongs to the G protein coupled receptor family , and it is consisted of a polypeptide chain containing 7 transmembrane domains . The GnRH-R encodes 327 / 328 amino acids .

根据蛋白N端有无信号肽和跨膜结构域，植物中的Formins蛋白被典型地分为I、II二类。

Because of signal peptide and a trans-membrane domain of N-terminal , Plant Formins can be divided into two subfamilies : type I and type II .

RTK有一个完整的开放阅读框，其编码的蛋白质具有信号肽和跨膜结构域，可能是一个具有磷酸化功能的跨膜蛋白。

RTK has a perfect ORF that code proteins with signal-peptide and transmembrane region . It is predicted that the product of RTK may be a transmembrane protein with phosphorylation site .

ECBP21cDNA全长947bp，编码216个氨基酸，序列分析显示其N端1-25氨基酸为信号肽，26-216氨基酸为成熟蛋白肽段，并且不具有跨膜结构域。

The cDNA contains 947 nucleotides that codes for a precursor protein of 216 amino acids . Sequence analysis shows that the N-terminal 1-25 amino acid sequence is a predicted signal peptide and other 26-216 amino acid sequence is a mature peptide which has no transmembrane domain .

然后进行了序列的测定，通过全序列分析，结果表明：所获得的8个抗病基因同源序列均含有NBS-LRR类抗病基因的保守序列，如P-loop（Kinase1a）、Kinase2、Kinase3a以及跨膜结构域等。

The sequence analysis indicated that eight of the nine analogues contained the conserved motifs of NBS-LRR of disease resistant genes , such as P-loop ( Kinase la ), Kinase 2 , Kinase 3a and trans-membrane domain .

关于信号肽和跨膜结构域的预测。

About signal peptide prediction and transmembrane region prediction ;

而同时缺失两个跨膜结构域时，导致蛋白改变了内质网的定位。

Expressed protein was not targeted to ER if both transmembrane domains were deleted .

胃质子泵β亚基仅有1个跨膜结构域，含有7个潜在的糖基化位点和3个二硫键。

While the β subunit formed only one transmembrane domain , and contained seven potential glycosylation sites and three disulfide bonds .

氨基酸疏水谱分析显示它有线粒体磷转运蛋白家族高度保守的6个跨膜结构域。

The hydropathy profiles of the deduced amino acid sequence predicted the existence of six membrane-spanning domains , which are highly conserved in the mitochondrial transporter family .

新生儿暂时性呼吸急促与上皮细胞钠离子通道编码基因多态性之间是否存在相关性：对α亚单位二次跨膜结构域的研究

Is transient tachypnoea of the newborn associated with polymorphisms in the epithelial sodium channel encoding gene ? Investigation of the second transmembrane spanning domain of the α subunit

我们运用多种生物信息学方法预测了该蛋白的物化特性、信号肽位点、跨膜结构域、抗原性、高级结构及其生物学功能。

We used multiple bioinformatics approaches to predict the physical and chemical characters , signal peptide , transmembrane domain , epitope , topological structure and function of the protein .

该蛋白含有明显的的丝氨酸/苏氨酸激酶激活位点签名序列，及胞外结构域，转膜结构域，丝氨酸/苏氨酸激酶结构域等三个重要结构域。

Sequence analysis revealed that there were three important domains : the extracellular domain , transmembrane domain and serine / threonine kinase domain . Also there were two distinct serine / threonine kinase active site signature sequences .

当MrpF截至一个跨膜螺旋结构域后，PhoA仍能表现出高度的活性，并且锚定于细胞膜。

When MrpF was truncated to only one transmembrane helix domain , PhoA still showed high activity , and still anchored in the cell membrane .

细胞膜微结构域中胆固醇对小鼠巨噬细胞摄取土拉弗朗西斯菌的作用

Role of cholesterol of membrane microdomain in the uptake of Francisella tularensis by mouse macrophages

质膜脂微区&一种新发现的膜局限性结构域

Membrane lipid microdomain ─ - a newly discovered membrane confined structure

以跨膜蛋白疏水结构域为多肽标签的目标蛋白酶定位研究

The Research of the Localization of Target Protein with Transmembrane Domain as Multi-peptide Tag

本文利用介孔碳的软模板合成方法和阳极氧化铝膜的孔道限域性制备有序的介孔碳纳米纤维。

Ordered mesoporous carbon nanofibers were prepared by combining the soft template synthesis method of mesoporous carbons with the confinement of channels of anode alumina membranes .

Cf蛋白定位于细胞质膜，但主体在膜外，主要结构域为富含亮氨酸重复（LRR）和跨膜结构域。LRR重复单元数目以及N端序列决定了Cf蛋白对Avr的识别特异性。

The Cf proteins , which are anchored at plasma membrane with the main body outside , mainly consist of a leucine-rich repeat ( LRR ) and a transmembrane domain .

该基因的开放阅读框长1083bp，编码1个含有360个氨基酸的跨膜蛋白，其结构域包括3个跨膜结构域和1个Popeye结构域。

The ORF of this gene is 1083 bps long , which encodes a 360-amino-acid transmembrane protein . It contains three transmembrane domains and one Popeye domain .

TRP通道均为六次跨膜蛋白，其N末端和C末端均在胞内，由第五和第六跨膜结构域共同构成非选择性阳离子孔道。

TRP channels are calcium permeable non - selective cation channels associated with six-transmembrane domains .