虚寒证

肢冷在虚寒证辨证中的意义及其代谢生物学基础的研究

The Research on the Significance of the Cold - limbs in the Differentiation of the Deficiency Cold Syndrome and Metabolic Bio - molecular Foundation

量表统计中，虚寒证患者四肢发冷项与对照组存在极显著差异（P＜0.01）；

In the deficiency patients scale , the patients of cold-limbs has obvious difference from control group ( P < 0 . 01 ) ;

[结论]①DU活动期以热证、虚寒证和气滞证为多，三者可否作为DU活动期基本证型有待进一步研究。

[ Conclusion ] Syndromes of active DU are mostly heat syndrome , asthenic cold syndrome and qi stagnation syndrome .

胃络瘀血证与脾胃虚寒证，胃络瘀血证与肝胃不和证，胃络瘀血证与脾胃湿热证患者舌质H值有显著差异（P<005）；

There were significant differences in the tongue H values between stomach blood-stasis syndrome and spleen-stomach deficiency-cold syndrome , liver-disharmony syndrome and spleen-stomach dampness-heat syndrome , P < 0.05 ;

综上所述，附子理中汤适用于治疗脾胃虚寒证的Hp感染疾病具有一定临床实用价值。

In conclusion , Fuzi-Lizhong Decoction has clinical practical value in the treatment of Hp infection with Deficient cold of spleen and stomach .

血浆GAS、SS水平下降的顺序是：瘀血证>郁热证>气滞证>对照组>阴虚证>虚寒证；

The levels of GAS and SS from the highest to the lowest were : blood stagnation syndrome > stasis heat syndrome > qi stagnation syndrome > control group > yin deficiency syndrome > asthenic cold syndrome ;

肝胃不和证与脾胃湿热证，肝胃不和证与胃阴虚证，肝胃不和证与脾胃虚寒证患者白苔H值有显著差异（P005）。

There were marked differences in the coating H values between liver-disharmony syndrome and spleen-stomach dampness-heat syndrome , stomach-yin deficiency syndrome and spleen-stomach deficiency-cold syndrome , P0.05 .

目的研究虚寒证的差异基因表达谱。

Objective To research differential gene expression profile of deficiency-cold syndrome .

大鼠虚寒证模型的研制

An Improved Rat Model of Cold Syndrome due to Yangqi Insufficiency

一个家系虚寒证的基因表达谱研究

A Research on Gene Expression Profile in One Pedigree of Deficiency-Cold Syndrome

虚寒证的辨证统计分析

The Statistical Analysis of the Syndrome Differentiation of Deficient Cold

虚寒证的脉象特点及脉图参数变化规律研究

Study on Pulse Features and Parameters of Yang-Deficiency Syndrome Patients

目的：虚寒证在人群中患病率高达9。

Objective : The morbidity rate of asthenia cold syndrome in crowd was9 .

目的：探讨温热药治疗虚寒证的分子机制。

Objective : To study the therapeutic molecular mechanism of the warm-hot drugs treating cold syndrome .

大鼠虚寒证模型部分指标相关性的初步研究

Primarily Study on the Correlation among the Part Results of Deficiency and Cold Syndrome Model of Rats

用激光灸与艾灸治疗虚寒证支气管哮喘的随机对照临床研究，观察其对哮喘患者肺通气功能的调整作用。

Patients of bronchial asthma characterized by cold deficient syndrome were divided into 2 groups at random .

单一证型中，小肠气滞证、小肠寒热失调证、小肠虚寒证、小肠湿热证较常见。

Among the single syndrome type , stagnation of qi , imbalance of cold and heat and damp - heat syndrome were most common .

虚寒证辨证因子等级量化标准的研究&分子中医研究系列报道（2）

Study on Quantitative Standard in Differentiation of Symptoms and Signs of Deficiency-Cold Zheng & Serial reports on molecular research of TCM ( 2 )

前言：“火”、“热”虽为血证急性期的基本病机，但亦不能排除虚寒证。

Although fire and heat are the basic pathogenesis of blood syndrome at its acute stage , deficiency and cold syndromes are not excluded .

目的对课题组近年探索虚寒证-基因组的研究进行概述，展示预选的代谢类基因功能模块。

ObjectiveTo summarize the latest development and achievement in genomes on asthenia cold syndrome , and demonstrate the metabolic gene function module preelected from asthenia cold syndrome-genome .

它提示了病人只有恶寒没有热感或发热，这是虚寒证的征象。

It implies that the patient only has an aversion to cold but no heat sensation or fever , which is a sign of the deficiency and cold syndrome .

生理学研究：选择10例骨关节炎虚寒证患者与10例正常人，从植物神经系数、交感皮肤反应、体表温度、植物神经反射等方面进行比较研究。

Physiology research : To compare the coefficient of visceral nerve , response of skin interaction , body temperature and visceral nerve reflection between 10 patients and healthy people .

目的：对比研究肾阳虚寒证患者血液生化、免疫指标以及差异基因表达谱的临床应用价值。

Objective : To study comparatively the potential clinical application of biochemical index , immunological index and differential expression gene profile on Kidney Yang-deficiency syndrome , a complicated Chinese medical syndrome .

目的：研究温针灸治疗膝骨关节炎虚寒证的临床疗效、并探讨其基因表达谱等方面的生物学基础。

Objective : To study the clinical effect of warm-needle acupuncture on patients suffering from osteoarthritic knee of cold-Zheng and to explore the molecular mechanism of the treatment through a biological point of view .

方法：1.临床证候及疗效研究：选取符合西医诊断标准的膝骨关节炎，中医辨证为虚寒证的66例患者，随机分为33例温针灸组与33例针刺组。

Method : 1 . Clinical research : 64 patients , selected by the diagnosis of TCM and western medicine , were randomly divided into 2 groups , namely warm-needle acupuncture group and acupuncture group .

胃宁合剂治疗虚寒证、气滞证、湿热证、血瘀证四种证型之间的有效率相近（P>005）。

The effective rates in four patterns of cold deficient syndrome , qi stagnation syndrome , damp heat syndrome and blood stasis syndrome treated with " Stomach Peace Mixture " were similar ( P > 0.05 ) .

肝胃气滞证和胃热炽盛证以浅表性胃炎为主（P<0.01），脾胃虚寒证和胃阴亏虚证以萎缩性胃炎为主（P<0.01）。

Main type of stagnation of liver-Qi and stomach-Qi syndrome and hyperactivity of stomach-heat syndrome was superficial gastritis ( P < 0.01 ) . Main type of deficiency cold of spleen and stomach syndrome and insufficiency of stomach-Yin syndrome was atrophic gastritis ( P < 0.01 ) .

目的：探求太阴病脾虚寒湿证与阳明病肠热腑实证辨证客观指标的差异性。

Objective : To distinguish indicators for syndrome differentiation between cold-dampness due to spleen insufficiency in Taiyin disease and solid-fu due to intestine-heat in Yangming disease .

归纳出四种基本证候类型：肝肾阴虚证、风邪入络证、脾肾亏虚寒凝证、气滞血瘀湿热证，并总结出各证候的辨证要点。

Summarized four basic syndromes : Liver and kidney certificate , pathogenic wind into the network card , spleen and kidney deficiency cold coagulation , blood stasis damp-heat syndrome , and summed the differentiation points syndromes .

聚类分析得出脾肾阳虚（虚寒）证、心脾气血两虚证、肺卫气虚（不固）证为慢性疲劳综合征基本证型。

Clustering analysis , spleen and kidney Yang ( cold empty ) card , glove deficiency of both qi qi deficiency syndrome , lung health ( not solid ) card for chronic fatigue syndrome basic card type .