西比灵

西比灵治疗脑出血继发脑水肿及ET-1、NSE的测定

Effect of Sibelium Treating Cerebral Edema Secondary to Hemorrhage and Determination of ET-1 and NSE

结论西比灵治疗VBI性眩晕疗效显著。

Conclusion Sibelium has significant curative effects on the vertigo caused by VBI .

西比灵干预对沙鼠脑缺血再灌注后核因子-κB、单核细胞趋化蛋白-1表达的影响

The effect of flunarizine on their expressions of NF - κ B and MCP-1 in ischemic brain tissue following cerebral ischemia / reperfusion in gerbils

西比灵治疗椎基底动脉供血不足的TCD和rCBF研究

Treatment of vertebrobasilar insufficiency with flunarizine Study on TCD and rCBF

西比灵干预对沙鼠脑内COX-2及PAI-1表达影响的研究

Study of Flunarizine on the Expressions of COX-2 and PAI-1 in Brain Tissue Following Transient Cerebral Ischemic Reperfusion in Gerbils

结论；西比灵能改善VBI患者脑循环，治疗VBI安全有效。

Conclusion : Flunarizine improves cerebrovascular circulation and it 's an effective drug for VBI .

结果：眩晕定方作用于气虚血瘀型血管性眩晕动物模型后，中剂量组体重为（2.54±0.13）kg，高于西比灵对照组的（2.06±0.10）kg，差异有显著统计学意义（P<0.01）；

Results : The weight of rabbits in the middle-dosage Xuan Yun Ding group was 2.54 ± 0.13 kg , high than that of control group treated with Flunarizine ( 2.06 ± 0.10 ) kg with remarkable significance ( P < 0.01 );

目的：研究椎基底动脉供血不足（VBI）患者服用西比灵治疗后脑血流动力学和脑血流量变化。

Objective : To evaluate the effect of flunarizine on cerebral blood hemodynamics and cerebral blood flow in patients with vertebrobasilar insufficiency ( VBI ) .

目的研究西比灵对大鼠急性脑缺血边缘系统细胞凋亡及bcl-2家族、白介素-1β转化酶（ICE）基因的影响及机制。

Objective To study the effect and the mechanism of sibelium on apoptosis and transcription of bcl 2 clan and interleukin 1 β converting enzyme ( ICE ) gene in limbic system after rats ' middle cerebral artery occlusion ( MCAO ) .

目的研究沙鼠脑缺血再灌注后脑内1型纤溶酶原激活物抑制剂（PAI-1）蛋白表达变化，以及西比灵干预的影响。

Objective To study the effects of transient cerebral ischemic reperfusion ( IR ) and flunarizine on the expression of plasminogen activator inhibitor-1 ( PAI-1 ) protein in brain tissue of gerbils .

西比灵合用妥泰预防偏头痛发作的临床研究

A Clinical Study of Sibelium Combining Topiramate in Prophylactic Treatment of Migraine

西比灵逆转抗癫痫药诱导的多药耐受基因表达

AEDs-induced Overexpression of Multidrug Resistance Gene Was Reversed by Sibelium

小剂量西比灵治疗偏头痛的临床研究

Clinical study of low dose of flunarizine treating the patients of migraine

西比灵对神经元损伤的保护作用

Protective effects of Sibelium on neuron injury in rats

西比灵合用免疫球蛋白治疗老年性癫痫69例临床观察

The Study of Flunarizine Combined with Immune Globulin for the Treatment of Senile Epilepsy

脑电地形图在西比灵治疗血管性头晕前后的应用研究

Applied Study on brain atlas after and before treatment by sibelium in ischemic vascular dizziness

目的探讨盐酸氟桂嗪（西比灵）对缺血损伤的神经细胞的保护作用。

Objective To observe the neuroprotective effects of Flunarizine hydrochloride ( sibelium ) during cerebral ischemia .

结论：西比灵合用免疫球蛋白对治疗老年性癫痫具有强化作用。

Conclusion : Flunarizine combined with immune globulin is an effective way of treating senile epilepsy .

目的：探讨西比灵对神经元损伤的保护作用机制。

Objective To study the protective effects of Sibelium on neuron injury in rats and its mechanism .

西比灵对大鼠急性脑缺血再灌注损伤自由基影响的实验研究

The effects of sibelium on the free radicals after acute cerebral ischemia reperfusion injury of the rats

给予西比灵（盐酸氟桂利嗪胶囊），2片/次，3次/日治疗。

Be given flunarizine ( flunarizine hydrochloride capsules ), 2 tablets / time , 3 times / day treatment .

目的：探讨西比灵合用免疫球蛋白作辅助性疗法治疗老年性癫痫的疗效。

Objective : To explore the efficacy of flunarizine combined with immune globulin as add on therapy for senile epilepsy .

方法应用西比灵胶囊口服、静脉滴注复方丹参注射液，配合颈椎牵引、正骨手法综合治疗。

Methods Application of oral Sibelium capsules , intravenous Salviae Miltiorrhizae Composita injection , with cervical traction , comprehensive treatment approach bonesetting manipulation .

2组均给予维脑路通、胞二磷胆碱、西比灵等药物治疗，治疗组在此基础上加用中药汤剂。

Venoruton , cytidine diphosphate choline and sibelium were given in both groups and Chinese herbal decoction was added in the treatment group .

然后再将高血压组大鼠随机分为三组：1、测体积组，又分为：西比灵组、妥泰组、缺血组、假手术组。

Group measured volume : consisted of sibelium group , topamax group , single ischemic group , fake operation group and normal rat group .

同时比较西比灵、拜阿司匹灵的预防效果，为预防性用药提供一定的实验依据。

We further compare the preventive effects of SBL with that of bay aspirin ( BAY-ASA ), to provide some experimental proof for preventive medical therapy .

目的观察针刺、走罐治疗椎动脉型颈椎病的临床疗效，并与口服西比灵片进行疗效比较。

Objective To observe clinical effect of cervical spondylosis of vertebral artery type through acupuncture combined moving cupping therapy , and to compare the effects of treatment of Sibelium .

方法：应用西比灵治疗300例缺血性血管性头晕患者，通过临床症征和脑电地形图观察其疗效。

Methods : 300 patients with ischemic vascular dizziness were treated by sibelium . The curative effect of sibelium was observed by clinical symptom and sign and brain atlas .

结果：西比灵治疗缺血性血管性头晕有效率为100.0%，脑电地形图在治疗前后有明显改变。

Results : The effective rate of sibelium in treatment of ischemic vascular dizziness was 100 . 0 % . The change of brain atlas was obvious before and after treatment .

目的：探讨西比灵治疗儿童偏头痛频繁发作的脑血流状态变化及临床意义。

Objective : To study the effects of sibelium on cerebral blood flow for children with frequent migraine , and the clinical significance of sibelium in the treatment of children migraine .