哮喘发作

无线电波可减轻哮喘发作引起的肺组织增厚。

These waves reduce the lung tissue which has been thickened by asthma attacks .

哮喘发作患者外周血嗜酸细胞差异表达基因克隆及特性研究

Cloning and Characterization of Differentially Expressed Genes in Peripheral Blood Eosinophils from Patients During Asthma Attacks

卵蛋白诱发哮喘发作时豚鼠大脑和肺内Fos蛋白的表达

Expression of Fos protein in brain and lung tissue of ovalbumin-induced asthmatic guinea pig

哮喘发作后血浆cGMP升高，淋巴细胞内无变化；

At asthma attack the cGMP in plasma rose but no change occurred in lymphocytes .

哮喘发作期PMN－CL明显高于缓解期（P＜0.01），缓解期高于正常对照（P＜0.05）。

The PMN-CL in stage of attack was significantly higher than in stage of remission ( P < 0 . 01 ), the latter was higher than that in healthy subjects ( P < 0.05 ) .

支气管哮喘发作期冷热哮证与ET-1、ANF关系的研究

Studies on Relationship Between Cold-heat Asthma at Stage of Attack of Bronchial Asthma and ET-1 and ANF

目的：通过动物和临床实验，研究肺表面活性物质（PS）在哮喘发作期对T淋巴细胞活化过程的影响。

Objective : To study the effect of pulmonary surfactant ( PS ) on the activation of T lymphocytes during an asthma attack by animal and clinical experiments .

小儿哮喘发作期中医证型与血清总IgE、过敏原的相关性

The Study of Relationship between the Allergen 、 T-IgE 、 EOS and TCM Cold and Heat Type of Childhood Bronchial Asthma during Attack

目的：研究哮喘发作时外周血嗜酸细胞（EOS）与细胞粘附及免疫调节相关基因的差异表达。

AIM : To determine differentially expressed genes associated with cell adhesion and immune regulation in peripheral blood eosinophils from asthmatic patients .

肺通气功能检查表明FEV1（第一秒钟最大呼吸量）与sIL-2R呈负相关，其相关性在哮喘发作时明显。

The pulmonary ventilation test showed that FEV1 and sIL-2R were negatively correlated , especially during an acute attack .

治疗后两组均能显著减少患者哮喘发作频率，统计结果显示治疗前后有显著性差异（P0.01）。

The two groups after treatment can significantly reduce the frequency of patients with asthma , before and after treatment there are significant difference ( P < 0.01 ) .

然而进一步研究显示，只有人鼻病毒（HRV）感染与哮喘发作明显相关，OR为2.38。

However , further analysis revealed that only human rhinovirus ( HRV ) infection was significantly associated with asthma attacks , at an OR of2.38 .

方法采用鸡卵蛋白（OVA）加Al（OH）3致敏大鼠，2周后用1%OVA溶液喷雾诱发大鼠哮喘发作。

Methods Rats models were made sensitive with OVA and Al ( OH ) 3 . Two weeks after , rats models were induced to asthma by spraying the solution of 1 % OVA .

轻度哮喘发作组4h和8h以及中度哮喘发作组4h的细胞计数与第1次相比，细胞总数和细胞分类均无显著性差异（P＞0.05）。

There was no significant change in the total and differential counts of the inflammatory cells in the 4h sample compared with the baseline ( P > 0.05 ) .

结论哮喘发作时患儿体内的HO1活性增加，与体内内源性一氧化碳、NO、cGMP和IgE水平增加相关。

Conclusions The increased activity of HO 1 in children with asthma was positively related to their levels of endogenous CO , cGMP , NO and IgE .

目的了解IL13在哮喘发作时水平及其与IgE的相互关系，从而探讨IL13在哮喘发病中的作用。

Objective To explore the effect of IL 13 in asthma pathogenesis .

目的评价应用硝苯地平与维生素K3治疗严重心肺疾病并发急性哮喘发作的疗效。

Objective To evaluate the effect of Nifedipine Vitamin K 3 in curing serious heart lung diseases with outbreak of acute asthma .

目的探讨儿童哮喘发作时血清一氧化氮（NO）、一氧化氮合酶（NOS）、丙二醛（MDA）活性变化及与肺功能的关系。

Objective To explore the relation between the change in activity of blood nitric oxide ( NO ), nitric oxide synthase ( NOS ), malondialdehyde ( MDA ) and lung function in children with paroxysmal asthma .

结论PS干预可以增加1型细胞因子，减少2型细胞因子，提示哮喘发作期PS能影响T细胞亚群分化，调整免疫发展的方向，在哮喘治疗上可能有重要的应用前景。

All these suggest that during an asthmatic attack PS can regulate the directions of T cell differentiation and alleviate airway inflammation , which indicates that PS might have an important future in the treatment of asthma .

哮喘发作患者病毒检测阳性为59例，鼻病毒为23例，流感病毒A和B为18例。结论临床缓解期患者并发上感后哮喘发作的比例为61.8%，3天后发作比例约为85.3%。

Rhinovirus ( RV ) were found in 23 patients , and influenza virus A and B ( IFAV ) in 18.Conclusion Asthma attacks rate among stable asthma patients with upper respiratory tract viral infection was 61.8 % , and it was 85 . % after 3 days .

目的：探讨大鼠孤束核（NTS）内组胺H3受体对哮喘发作时大脑Fos蛋白表达的影响及其意义。

Objective To explore the effect of histamine H_3 receptors in nucleus tractus solitarius ( NTS ) on c-Fos expression in the brain of rats with asthma onset .

对52例支气管哮喘发作期患者进行了外周血T细胞亚群、IgG4、IgE、sIL－2R、ACTH及皮质醇的测定。

Cell subgroup , IgG 4 , IgE , sIL 2R , ACTH and cortisol in 52 patients peripheral blood with bronchial asthma onset phase , as well as 50 controls were measured .

目的探讨扶正化瘀平喘法对哮喘发作患儿血清白细胞介素5（IL-5）、白细胞介素8（IL-8）的影响。

Objective : To investigate effects of method for strengthening the body resistance , removing blood stasis and relieving asthma on serum interleukin-5 ( IL-5 ) and interleukin-8 ( IL-8 ) in asthma attack children .

Dot-blot、Northern-blot分子杂交及免疫组织化学技术观察哮喘发作前、后豚鼠气道上皮及肺组织中c-fos、c-myc、c-jun和c-sis的表达及其与炎症细胞浸润的关系。

Dot-blot , Northern-blot and immunochemical techniques were used to detect the expression of c-fos , c-myc , c-jun and c-sis . Inflammatory cell infiltration was showed by pathologic study .

rIL-12和rIFN-γ可抑制气道肥大细胞的聚集与哮喘发作

Inhibition of accumulation of mast cells in the airways and asthma attack by rIL-12 and rIFN - γ

目的研究早期接触屋尘螨（HDM）能否加重后期哮喘发作时的气道炎症及其相关免疫学机理。

Objective To study whether early exposure to house dust mite would aggravate airway inflammation as long as the onset of asthma and to explore relevant mechanisms .

结论布地奈德联合沙丁胺醇雾化吸入可显著降低急性哮喘发作患儿气道分泌物内嗜酸性细胞、中性粒细胞和单核细胞数量及IL-8、IL-6、TNF-α水平。

Levels of IL-8 、 IL-6 and TNF - α were elevated during the acute exacerbation and decreased at resolution . Conclusion Therapy of inhaled budesonide and salbutamol can reduce inflammatory cells and cytokines concentrations in induced sputum from children with an acute exacerbation of asthma .

结果显示哮喘发作期IgG4、IgE、sIL－2R及ACTH均显著升高，提示哮喘患者存在细胞免疫及内分泌功能的异常。

The levels of IgG 4 , IgE , sIL 2R and ACTH in asthma patients were significantly higher compared to those of controls . The results suggest abnormality of cell immunity and endocrinic function in asthma onset phase .

进行社区整体管理计划，推行GINA和综合防治措施，可有效控制哮喘发作，减少医药费用支出，提高患儿生活质量。

Community integrated management plan , the implementation of GINA and comprehensive prevention and control measures , which can effectively control the occurrence of asthma , reduce medical costs , improve the quality of life of patients.18 .

同时选择小儿哮喘发作期（寒热夹杂型）30例作为哮喘组，正常健康儿童30例作为正常组，并同时观察这两组的尿LTE4水平。

30 healthy children were used as the normal control group . 30 asthmatic cases were taken as the asthma group . The levels of urine LTE4 were also determined in these two groups .