多重耐药菌

ICU医院感染多重耐药菌类型、耐药性及感染相关因素研究Necroptosis克服肿瘤多药耐药性

Analysis of bacterial type , drug resistance and infection related factor of multi-drug resistant strains of nosocomial infection in ICU patients

Logistic回归分析表明只有院内感染、抗生素应用时间与发生多重耐药菌感染有关。

By multivariable logistic regression analysis , We found only nosocomial infection and duration of antibiotic treatment before infection were the risk factors for antibiotic multi-resistance bacterial infection .

结论医院获得性MRSA是多重耐药菌，ICU的MRSA菌株主要基因型为A、B型。

Conclusions Hospital acquired MRSA is multi-resistant to antibiotics . Genotypes A and B are prevalent MRSA in ICU .

结论产ESBLs鲍曼不动杆菌常为多重耐药菌，耐药率与产ESBLs密切相关；

Conclusion ESBLs producing strains usually were muti-drug resistance and the drug resistant rate was closely associated with ESBLs .

结果ICUVAP获得性感染病原菌多为多重耐药菌，其中G-菌占56.3%，G+菌占23.0%，真菌占13.7%。

RESULTS Pathogenic bacteria of VAP in ICU mostly were multidrug-resistant ones , of which the G-were 56.3 % , G + were 23 % and fungi were 13.7 % .

结果48株亚胺培南耐药菌株均为多重耐药菌，对临床常用的多种抗菌药物耐药，敏感率由高到低依次为CIP、TOB、AMK、GEN和FEP；

RESULTS All isolates were multiresistant , the orders of sensitivity rates of antibiotics were CIP , TOB , AMK , GEN , and FEP .

结论G-菌是多重耐药菌的主要构成菌，对常用抗菌药物几乎全部耐受，其耐药机制主要是细菌产生ESBLs和AmpC等灭活酶。

Conclusion The major multiply drug-resistant bacteria were gram-negative bacilli , the most common mechanisms of resistance include production by bacteria of antimicrobial-inactivating enzymes , such as ESBLs and AmpC .

SICU多重耐药菌定植感染监测及传播动力学研究空间扩散的传染病动力系统行波解研究

Transmission Dynamics and Monitoring of Multi-drug-resistant Bacteria Colonization and Infection in a SICU The Studies of Travelling Wave Solutions in Epidemic Dynamics System with Diffusion

然而，目前国内外抗菌药物滥用的问题十分突出，导致耐药菌急剧增多，其中耐甲氧西林金黄色葡萄球菌（Methicillin-resistantstaphylococcusaureus，MRSA）是一种引起医院内获得性感染的多重耐药菌。

However , it is very outstanding at present that antibiotic is abused in domestic and abroad , which results the antibiotic-resistant bacteria to increase sharply . Methicillin-resistant staphylococcus aureus ( MRSA ) is one of the most important multidrug-resistant bacterium in the hospital .

同时还测定了Aztreonam对81株多重耐药菌的抗菌作用，其中只有13株菌的MIC大于8μg/ml，总抑菌率为84.0%。本研究为Aztreonam的临床应用提供了参考。

The antibacterial activity of aztreonam against 81 multiresistant Gram-negative bacilli was quite good , the MICs of only 13 strains were > 8 μ g / ml and 84.0 % of strains were susceptible to aztreonam .

研究背景预防与控制医院多重耐药菌（MDRO）感染，是目前国内外医院面临的巨大挑战。

Background : Currently , multi-drug resistant Organism ( MDRO ) infection prevention and control is faced with enormous difficulties and challenges in hospital infection management .

厄他培南&治疗多重耐药菌感染的新选择

Ertapenem & a newly treatment for infection of severe drug-resistent Pathogens

多重耐药菌的医院感染控制工作实践与体会

Practice and experience in controlling nosocomial infection of multi-drug resistant bacteria

国产美罗培南治疗多重耐药菌感染的临床观察

Domestic Meropenem in Treatment of Infection for Multi-drug Resistant Bacteria : A Clinical Study

呼吸系疾病多重耐药菌感染的中医证型及易患因素观察

Multiple Drug-resistant Infection of Respiratory System Diseases ' Observation on TCM Syndrome and Risk Factors

多重耐药菌消毒剂抗性和精氨酸代谢移动元件研究

The Study on the Susceptibility of Biocides and the Arginine Metabolic Mobile Element in Multidrug-resistant Bacteria

肝炎肝硬化患者发生多重耐药菌感染病例危险因素分析

Investigation of risk factors for antibiotic multi-resistance bacterial infection in patients with liver cirrhosis by case-control study

新型高效抗微生物肽的优化设计与合成及其体内外抗多重耐药菌的研究抗生素和抗真菌药物混合而成的药物。

Optimum Designing of New Potent Antimicrobial Peptides and Their Effects on Multidrug Resistant Bacteria an antibiotic and antifungal agent .

结论条件致病菌是感染菌谱中的主要病原菌，多重耐药菌的增多和混合感染是医院面临的重要问题。

Conclusion Opportunistic pathogens were the main pathogens , multiply drug resistant strains and mixed infection were important problems in hospital .

由于这些多重耐药菌引起的严重感染已经成为临床治疗的一大难题，迫切需要一种药物能够有效地治疗这类感染。

The treatment to the severe infections caused by these multi-drug resistant bacteria has been a big problem in clinical healings .

结果表明，部分化合物对革兰氏阳性菌具有较大的抑菌能力，特别是多重耐药菌。

The results demonstrated that some compounds presented great antimicrobial activities against Gram positive bacteria , including the multidrug-resistant clinical isolates .

但是，国内缺乏系统性的黏杆菌素抗多重耐药菌药效学方面的研究，不能给兽医临床用药给予指导性的意见。

However , lacked of systematic research on pharmacodynamics of colistin , the guiding opinions was could not been given to veterinary clinic .

研究发现，胶州湾多抗性细菌污染严重50%的多重耐药菌携带整合子；

Clone and DNA sequencing were used to analyze the resistance-related gene cassettes . 50 % of multidrug resistance isolates were detected with integron .

目的：用病例对照研究探讨肝炎肝硬化患者发生多重耐药菌感染的危险因素。

Objective : To make an inquiry into the probable risk factors for antibiotic multi-resistance bacterial infection in patients with liver cirrhosis by case-control study .

结果显示，92%的受试菌对伊米配能敏感，仅3.9%的金葡菌和9.8%的绿脓杆菌对其耐药，大多数多重耐药菌对伊米配能仍敏感。

Results showed that 92 % strains tested were sensitive to imipenem and only 3.9 % Staph . aureus and 9.8 % P. aeruginosa resistant to it .

对治疗腹腔感染、复杂性尿路感染、复杂性皮肤及附属器感染及多重耐药菌引起的感染疗效较高；

Clinically it is used in the treatment of complicated intra-abdominal infection ( cIAI ) and complicated urinary tract infection as well as infection from severe drug-resistent pathogens .

结论随着临床抗菌药物的广泛应用，多重耐药菌增加了治疗难度。

CONCLUSIONS Along with the wide application of antibiotics , it is more difficult to cure the infection by the bacteria whose drug resistance to commonly used antibiotics is high .

结果：单因素分析发现院内感染、插管、血清总胆红素、抗生素应用时间为肝炎肝硬变患者发生多重耐药菌感染的可能危险因素。

Results : A univariable analysis showed that nosocomial infection , intubatton , serum total bilirubin and duration of antibiotic treatment before infection were the risk factors for multi-antibiotic resistance .

结论：控制院内感染、合理应用抗生素可以减少肝炎肝硬变患者发生多重耐药菌感染的风险。

Conclusion : Efforts should be emphasized on controlling nosocomial infection and judicious using of antibiotics , which may decrease the risk of antibiotic multi-resistant bacterial infection in patients with liver cirrhosis .

结果32株伤寒沙门菌对氧氟沙星、环丙沙星、头孢噻肟、哌拉西林、氯霉素、四环素、庆大霉素的耐药率分别为0、0、0、28.13%、43.75%、40.63%和12.5%，其中多重耐药菌10株。

( Results ) The antibiotic resistant rates of S.typhi to ofloxacin , ciprofloxacin , cefotaxime , piperacillin , chloramphenicol , tetracycline and gentamicin were 0,0,0,28.13 % , 43.75 % , 40.63 % and 12.5 % , respectively .