抗体生成

胰岛素免疫原性的临床研究：胰岛素纯度与抗体生成、用药剂量和血糖控制的关系

A clinical study of the immunogenicity of insulin : effect of impurity of insulin on insulin antibody formation , insulin dosage and blood glucose normalization

景蜂胶囊0.4,0.8,1.2g/kg组小鼠的溶血素抗体生成水平均显著高于空白对照组（P<0.05～0.01）。

Level of antibody formation of erythrolysin in mice of 0.4 g / kg , 0.8 g / kg and 1.2 g / kg group were remarkably higher than the blank control group ( P < 0.05-0.01 ) .

表明二蒽酮类能够增强B淋巴细胞的分化与增殖，并促进其抗体生成，增强体液免疫的功能。

The findings suggested that dianthrone can enhance the differentiation and proliferation of B lymphocytes , and promote the antibody generated to enhance the humoral immune function . 4 .

小鼠IgE抗体生成的免疫调节&对半抗原-载体蛋白质IgE抗体应答的研究

Regulation of IgE antibody production in mice ⅲ . IgE antibody response to hapten-carrier conjugate

鸡贫血病雏鸡ND免疫后局部免疫组织抗体生成细胞变化

Changes of the number of antibody-producing cells in the local immune tissues post ND vaccination of Chicks infected with chicken anemia virus

基于主从Self集的抗体生成算法通过动态扩大从Self集，以扩大Self集合中的元素，使经过免疫耐受生成的抗体提高对抗原的识别能力。

PASA achieve the dynamic expansion of the Self-set by adding the subordinate Self-set and the antibodies generated by immune tolerance enhance the space of antigen recognition space .

体液免疫功能测定：（1）抗体生成细胞检测（PFC）结果为阳性，（2）血清溶血素测定结果为阳性。

The humoral immunity test indicated that the result of PFC and blood serum hemolysin test were positive too .

分别采用MTT法和ELISA法检测淋巴细胞增殖活性及抗ANT抗体生成水平。

The Method of MTT was used to detect B cell proliferation activity , and ELISA was given to measure the levels of anti-ANT antibody .

结果：0.28、0.84g/（kg·d）组可增强小鼠的淋巴细胞增殖能力、提高小鼠抗体生成细胞水平及小鼠碳廓清的能力；

Results : 0.28 ? 0.84 g / ( kg · d ) of PVR could improve the proliferation ability of lymphocyte , the level of antibody-making cells and the ability of macrophage .

分枝杆菌多糖（MPS）对小鼠抗SRbc抗体生成细胞增强作用的观察

The Observation on the Enhanced Effect of Mycobacterial Polysaccharides ( MPS ) on Anti-SRbc Antibody Forming Cells in Mice

结论：ASI能够促进小鼠T、B淋巴细胞的增殖和抗体生成，同时可以抑制腹腔巨噬细胞体外分泌IL-1和TNF-α。

CONCLUSION : ASI increased T , B lymphocyte proliferation and antibody production in vivo and in vitro ; but inhibited productions of IL-1 and TNF - α from peritoneal macrophages in vitro .

结果：抗生育剂量的T7并不影响小鼠的非特异性免疫功能，抗生育剂量的T7对抗体生成有抑制作用，但对B细胞的免疫功能有促进作用。

Results : T 7 did not affect the nonspecific immunity in mice , and it can inhibit antibody production whereas it could promote the immunity function of B cell .

本文采用小鼠碳粒廓清、植物血凝素（PHA）诱导淋巴细胞转化，以及血清溶血素和抗体生成细胞测定等实验，研究南美植物玛咖的乙醇提取物对正常小鼠免疫功能的影响。

Oral administration of ethanol extract of Maca significantly increased the rate of transformation of lymphocyte induced by PHA and it also promoted production of hemolysin in serum and an .

目的：以促黄体生成素释放激素融合蛋白（TrxLHRH）为免疫疫苗，氢氧化铝为佐剂，研究TrxLHRH诱导雄性大鼠抗体生成及其对大鼠生殖功能的影响。

Objective : To investigate the effect of Trx-LHRH , a new GnRH crasis protein , on antibody production and male reproductive function .

结果给药组SRBC抗体生成水平和卵清抗体生成水平显著高于对照组（P<0.05），两组血清中IL-2的变化无显著差异。

Result : Levels of anti-SRBC , anti-ovalbumin antibodies were higher in experimental group than that in control group ( P < 0.05 ), while concertrations of IL-2 showed no significant difference .

本研究测定了日粮中添加0～128μg/g维生素A（VA）时，雏鸡20～35d对β酪蛋白抗原刺激时特异抗体生成水平及T淋巴细胞增殖活性。

The effect of dietary Vitamin A ( VA ) on antibody production and T lymphocytes proliferative response was determined in chickens from 20 to 35 d old .

三价苗免疫鸡的抗体生成细胞显著多于HVT疫苗免疫鸡。

There were markedly more antibody-producing cells in the immune organs and tissues of the trivalent vaccine-immunized chicks than those of HVT vaccine-immunized birds .

采用血清抗体生成方法测定小鼠溶血素和采用二硝基氟苯（DNFB）诱导的小鼠局部迟发超敏DTH反应，并记录其胸腺指数和脾指数。

Hemolysin of mice was measured by serum antibody check method and local delayed-type hypersensitivity ( DTH ) was induced by dinitrofluorobenzene ( DNFB ), and thymus exponent and spleen exponent were recorded .

黄芪甲苷（astragalosideIV，ASI）是黄芪中的有效成分之一，具有抗炎，改善心肌，脑缺血，促淋巴细胞繁殖，促抗体生成等作用。

Astragaloside IV ( ASI ) is the effective compound of Astragalus membranaceus according to China Pharmacopoeia . Studies showed that ASI could exhibit anti-inflammatory function , improve cerebral and myocardial ischemia , and increase lymphocyte proliferation and antibody production .

结果α-亚麻酸能提高小鼠的抗体生成细胞数和血清溶血素水平，促进小鼠的单核-巨噬细胞的碳廓清和腹腔巨噬细胞的吞噬能力，促进小鼠的迟发型变态反应，提高小鼠NK细胞的活性。

Results α - Linolenic acid was capable of increasing the quantity of antibody-producing cells and the level of serum hemolysin , promoting the expurgation effect and the phagocytic function of monocyte / macrophage , stimulating delayed hypersensitivity and strengthening the activity of natural killer cells .

结果表明：人参皂甙Rh2注射液能提高荷瘤小鼠腹腔巨噬细胞吞噬功能、增加血清溶血素抗体生成能力、促进小鼠脾NK细胞杀伤活性和IL-2活性。

The activity of natural killer ( NK ) cells and IL-2 in the splenocyte of cancer mice were observed . Ginseng saponin Rh2 injection could increase the phagocytic percentage of abdomen macrophage and promote the production of serum hemolysin antibody .

对SPF雏鸡人工感染REV后局部免疫组织盲肠扁桃体和哈德氏腺的IgA、IgG和IgM抗体生成细胞数量动态变化进行了检测。

This experiment was conducted to study the dynamic changes of lgG , lgM , lgA antibody producing cells in the cecal tonsil and Harderian gland , the local immune tissues from specific free ( SPF ) chickens inoculated with reticuloendotheliosis virus ( REV ) .

经口服给予小鼠不同计量的乳酸菌骨泥发酵液30d，能够明显提高小鼠的抗体生成细胞数、足跖细胞及巨噬细胞功能。

Bone mud fermented by lactic acid bacteria had been given to the mouse orally in different amount for 30 days . The result revealed that the number of cell in claw and M in mouse .

根据鸡新城疫I系疫苗（NDI）免疫剂量不同，将200只2周龄健康雏鸡随机分成4组，检测免疫器官中IgG抗体生成细胞的动态变化及接种后ND抗体消长的变化。

Two week old chickens were randomly divided into four groups , serum and immune organs were collected to detect Ab against ND change in blood , to detect the growth and decline pattern of IgG as well as dynamic development of IgG producing cells .

对感染鸡贫血病毒（CAV）雏鸡新城疫（ND）疫苗免疫及其强毒攻击后局部免疫组织&盲肠扁桃体和哈德尔腺的IgA、IgG和IgM抗体生成细胞数量的动态变化进行了检测。

The experiment was undertaken to detect the dynamic changes of the number of the IgA , IgG , lgM antibody-producing cells in the local immune tissues , cecal tonsil and Harderian gland , post ND vaccination of chicks infected with chicken anemia virus ( CAV ) at one-day old .

近年来研究发现免疫细胞发生ERS在细胞功能调控中起重要作用，如抗原提呈、浆细胞分化、抗体生成以及T细胞对抗原反应等。

Recently , emerging evidence indicates that ERS in immune cells has been shown to play an important role in the regulation of the cellular functions , such as antigen presentation , plasma cell differentiation and antibody production , and T cell response to antigen .

方法：分别灌胃给予小鼠肝愈胶囊0.125,0.25及0.5g/kg，连续7d，测定肝愈胶囊对小鼠免疫器官脾、胸腺指数、单核巨噬细胞吞噬功能、溶血素抗体生成、迟发型超敏反应功能的影响。

Methods : Feed mice with 0.125, 0.25 and 0.5 g / kg of Ganyu Capsule continuously for 7 days , then determine the spleen index , chest gland index , phagocytosis of monocytes-phagocytes , hemolysin formation lever and DTH test .

结果：LSPC可抑制小鼠S180肉瘤生长、提高免疫器官的增长指数；能显著增强荷瘤小鼠巨噬细胞的吞噬功能、DNFB所致迟发型超敏反应以及抗体生成的能力。

Results : LSPC could inhibit the growth of S180 sarcoma in mice , increase the growth index of immune organs , significantly enhance the phagocytosis function of peritoneal macrophage ( PM Φ), intensify DTH caused by DNFB , and increase production of antibody .

针对抗体生成算法复杂度高、生成抗体检测率低和抗体集合庞大的问题，提出了基于多种群遗传算法的抗体生成算法（MPTMA）。

In order to decrease complexity of antibody maturation algorithm , improve detection rate and smaller antibody set , multiple population GA based antibody maturation algorithm ( MPTMA ) is put forward .

乙酰胆碱对大鼠体外抗体生成的影响

Effect of acetylcholine on the antibody synthesis of rats in vitro