抗凝血药

香豆素类抗凝血药华法林及其类似物的合成

The Synthesis of Coumarin Anticoagulants Warfarin and It 's Analogs

香豆素类抗凝血药是唯一一类口服参与体内代谢才发挥抗凝作用的药物，称为口服抗凝血药。

Coumarin anticoagulants , called oral anticoagulant are a pharmaceutical taken orally to participate intravital metabolism .

制药工业研究公司DecisionResources预测说，如果新药成功的话，抗凝血药市场将从去年的三十亿美元翻一番增加到2016的七十四亿美元。

Drug industry research firm Decision Resources predicts that , if successful , the new drugs could double the size of the anti-coagulant market from $ 3 billion last year to $ 7.4 billion in2016 .

华法林（Warfarin）是临床广泛应用的一种常用的抗凝血药，主要用于预防和治疗体内的各种凝血疾病。

Warfarin is an anticoagulant widely used in the treatment and prophylaxis of various thromboembolic disorders .

阿司匹林还能抑制血小板凝聚，是一种有效的抗凝血药，可让罹患冠状动脉心脏病的病人预防心肌梗塞。

It also has anticoagulant activity and is taken in low doses by coronary heart disease patients to prevent heart attack .

华法林属双香豆素衍生物，是常用的口服抗凝血药，可预防和治疗血栓栓塞性疾病。

Warfarin , a coumarin derivative , is widely used as an oral anticoagulant drug in the treatment and prevention of thromboembolic disorders .

如果正确服用，这种抗凝血药可以显著降低高风险患者中风的几率，但是，研究人员表示，高达40%的患者未能坚持服用。

The blood-thinning drug can sharply reduce the chance of stroke in high-risk patients if taken correctly , but researchers say as many as40 % of patients don 't.

抗凝血类灭鼠药所致凝血功能障碍8例

Clinical Analysis of 8 Cases with Coagulation Disorder Caused by Anticoagulant Rodenticides Poisoning

Mannich碱及其衍生物最初是作为药物而得到应用的，在医药方面可以做镇静止痛药、杀菌剂、水肿抑制药、抗肿瘤药、保肝药、抗凝血药。

Mannich base and its derivatives firstly are used for drug application , such as sedation analgesia drugs , microbicides , edema inhibitors , antineoplastic agents , detonator and anticoagulants .