临床前研究
- 名preclinical study
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临床前研究证实,多西他赛与紫杉醇无完全交叉耐药。
It has no complete cross-resistance with paclitaxel according to preclinical study results .
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在进行医疗器械的临床前研究过程中,人因可靠性是影响临床前研究结果有效性的重要因素。
During the course of preclinical study of the medical devices , human factors are important to affect reliability and the effectiveness of preclinical studies .
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重组腺病毒介导人野生型p53、GM-CSF和B7-1基因对恶性肿瘤生物治疗的临床前研究
Pre-clinical Study on Bio-therapy of Malignant Tumor with Human Wild-Type p-53 , GM-CSF and B7-1 Genes Mediated by Recombinant Adenovirus Vector
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RoyFreeman教授:基于临床前研究的数据和最近的临床资料,有许多生化途径在神经变性的功能障碍中发挥着关键作用。
Prof Roy Freeman : There are a number of biochemical pathways based on preclinical data and more recently clinical data which play a key role in dysfunction of nerve degeneration .
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综合临床前研究方法学的进展,文章主要对BMSC的细胞类型、细胞移植的时间窗、细胞移植途径、移植细胞后体内追踪技术以及治疗效果评价等方面的最新进展做了综述。
Synthesizing the advances in methodology of preclinical studies , this article mainly reviews the types of BMSC , time window for cell transplantation , approaches of cell transplantation , tracing technique in vivo after cell transplantation , and treatment effectiveness evaluation .
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临床前研究,Ⅰ和(或)Ⅱ期临床试验都已证实,HDAC的小分子抑制剂能够有效地促进抑癌基因表达,抑制肿瘤生长并诱导细胞凋亡。
Small molecular inhibitors of HDAC inducing histone acetylation are highly effective in up-regulating tumor suppressor gene ex - pression , repressing tumor growth and inducing apoptosis in preclinical studies and in phase ⅰ and ⅱ clinical trials .
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我国有关单位开发的PEG-rhIL-6新型药物也正处于临床前研究阶段。
A new biological drug - PEG-rhIL-6 developed by a graduate school of China is also in the clinical stage of registration study . Several techniques can be used to study the pharmacokinetics of a new biological product .
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临床前研究为临床问题的解决提供了重要依据。
Preclinical researches can provide important evidences in solving clinical problems .
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硫代反义寡核苷酸药物癌泰得的临床前研究
Preclinical Research of Phosphorothioate Antisense Oligonucleotide Named " Cantide "
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在临床前研究中,巴多昔芬不会刺激子宫内膜。
Bazedoxifene , in the preclinical work , protected against endometrial stimulation .
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表面渗氮处理纯钛的基础及临床前研究
The Basic and Pro-clinical Research of Pure Titanium Surface Treated by Plasma Nitrided
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临床前研究中肝损伤的临床病理指标的选择及意义
Selection and Interpretation of Clinical Pathology Indicators of Hepatic Injury in Preclinical Studies
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临床前研究和临床试验研究显示该药对多种肿瘤有抗肿瘤活性,不良反应较轻。
Preclinical researches and clinical trails show its anti-tumor activity with slight side effects .
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另外还有临床前研究的资料证实这些药物对于蛋白尿也有一定的治疗效果。
There is also pre-clinical evidence of the favorable effect on proteinuria for example .
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喉癌基因治疗的临床前研究
Preclinical Studies on Gene Therapy for Laryngeal Carcinoma
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癌症基因治疗联盟-资助临床前研究;
Alliance for Cancer Gene Therapy-preclinical studies ;
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肝细胞移植临床前研究:大鼠肝细胞分离、培养和逆转录病毒转导
Preclinical studies for liver cell transplantation : isolation , culture for rat hepatocytes and retroviral transduction
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许多类型的内皮素受体拮抗剂在各种动物模型上进行了临床前研究,一些已经进行了临床研究。
Many endothelin receptor antagonists have been synthesized and evaluated in animal models and in human .
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造血干/祖细胞的体外定向诱导分化的临床前研究
Studies On the Committed Differentiation of Hematopoietic Stem / Proginetor Cells ex vivo for Clinical Trial
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惠氏的一位发言人称这是一项“有趣的临床前研究”,并表示该公司也是刚刚得知有关的研究发现。
Wyeth spokesman called it an'interesting preclinical study'and said Wyeth just became aware of the finding Wednesday .
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药物质量控制和稳定性研究是药物临床前研究的一个重要内容。
The research on quality control and stability of drugs is an important part of drug pre-clinical studies .
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本文从免疫毒理学的角度综述了这门学科在新药安全评价中的应用,包括新药对免疫系统的副作用、临床前研究中对免疫系统的检测方法和注意事项。
This paper summarizes the side effects , and the methods for checking and notices of new drugs .
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这些缺点包括临床前研究和取样规模不足,试验地点准备不佳以及缺乏社区的参与。
Shortcomings have included inadequate pre-trial research and sample size , poor site preparation and lack of community engagement .
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研究结论:(1)我国的临床前研究中引入项目管理,有助于管理质量的提高。
Conclusion : ( 1 ) Project management theories can improve the management level of the preclinical research of our country .
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其临床前研究(包括异常毒性实验、细菌及细菌内毒素的检查)各项指标均符合中国药典标准。
Preclinical studies including sterility , endotoxin and toxicity tests were performed and the results accorded with the standards of Chinese Pharmacopoeia .
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同时,制得可供临床前研究用相转变温度为41℃的喃氟啶温度敏感性脂质体。
The temperature sensitive liposomes of futraful with T C of41 ℃ were prepared which consisted of60 % DPPC and40 % DSPC .
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甲氨蝶呤磁性抗癌新药的临床前研究硫代反义寡核苷酸药物癌泰得的临床前研究
Preclinical Study of New Anti-tumor Drug of Magnetic Albumin Microspheres Combining MTX Preclinical Research of Phosphorothioate Antisense Oligonucleotide Named " Cantide "
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“这些临床前研究数据为抗坏血酸应用于人类肿瘤治疗的后续药理学研究打下了坚实基础。”研究人员总结道。
" These pre-clinical data provide the first firm basis for advancing pharmacologic ascorbate in cancer treatment in humans ," the researchers conclude .
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应用她的实验室开发的一种基因工程小鼠,一种名为雷帕霉素的现有药物已经开始临床前研究。
Using the genetically engineered mice her lab developed , one preclinical study is already under way , testing an existing drug called Rapamycin .
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树突状细胞介导的抗胃癌过继免疫治疗的临床前研究三种不同支抗形式拔牙矫治青少年双颌前突的临床研究
Preclinical Study of Adoptive Immunotherapy Against Gastric Cancer Induced by DC Three kind of anchorage on bimaxillary protrusion of adolescents : a clinical comparative study