血药浓度监测

血药浓度监测与毒物中毒的临床分析

Analysis of Clinical Data About TDM and Poison Toxicosis

结论：该方法简便、准确，适合于临床血药浓度监测。

CONCLUSION : The method was convenient , rapid , accurate and suitable for TDM .

国产环孢素A微乳胶囊血药浓度监测指标C2与C0的比较

Comparison between C_2 and C_0 as a monitoring tool for domestic cyclosporin A microemulsion capsule

结论：PB血药浓度监测在临床癫痫治疗中具有重要指导意义。

Conclusion : The PB blood concentrations is important in the clinical epilepsy treatment .

目的：建立人血浆中福辛普利拉HPLC测定法，为血药浓度监测和临床合理用药提供方法学基础。

Objective : To establish a HPLC assay method for the determination of fosinoprilat in human plasma .

目的建立全血中环孢素A（CsA）的HPLC测定方法，并用于临床血药浓度监测。

OBJECTIVE To establish a HPLC method for the determination of cyclosporine A in whole blood .

因此，5-FU血药浓度监测和毒副反应严重程度的预测具有重要的临床意义。

So monitoring serum concentration and predicting toxicity of 5-FU mean clinical sense .

肝移植患者术后早期CsA血药浓度监测

The therapeutic drug monitoring of the early stage of CsA after liver transplantation

目的：考察不同分析方法对环孢素A（CsA）血药浓度监测中的影响。

OBJECTIVE To examine the effect of assay methodology on variability in blood concentrations .

目的：探讨肝移植（OLT）受者环孢素A（CsA）合理的血药浓度监测指标。

OBJECTIVE To investigate the blood level monitoring of CsA for liver transplantation patients .

结论：该方法灵敏，准确，抗干扰性好，适用于儿科临床血药浓度监测及其药动学研究。MTX在ALL患儿体内的经时过程呈一房室模型代谢。

CONCLUSION The method is sensitive , accurate for monitoring the MTX blood concentration .

排泄延迟更易出现于使用高剂量药物时。在血药浓度监测下使用大剂量MTX安全可行。

Application of high-dose MTX therapy under the monitoring of blood MTX concentration is safe and feasible .

目的：制订肾移植病人中麦考酚酸（MPA）的血药浓度监测的有限采样法方案。

AIM : To investigate limited sampling strategies ( LSS ) for clinical plasma monitoring of mycophenolic acid ( MPA ) in renal transplantation patients .

方法：以荧光偏振免疫法（FPIA）对194例癫痫患儿进行血药浓度监测。

Method : The serum concentrations of194 children with epilepsy was monitored by fluorescence polarization immunoassay ( FPIA ) .

方法：利用荧光偏振免疫分析法（FPIA）对135例癫痫病人进行PB血药浓度监测，并对测定结果进行分析。

Methods : 135 epilepsy patients were monitored the PB blood concentrations by FPIA method and the result were analyzed .

摘要：目的探讨血药浓度监测在大剂量甲氨蝶呤（MTX）治疗血液系统肿瘤中的应用价值。

ABSTRACT : Objective To explore the clinical value of blood concentration monitoring during high-dose methotrexate ( MTX ) treatment .

CsA血药浓度监测对制定给药方案、肾毒性和排斥反应的鉴别，有重要的临床意义。

CsA therapeutic drug monitoring has great significance on drafting the clinical protocols for CsA and differentiation of the nephrotoxicity and allograft rejection .

目的：探讨大剂量氨甲蝶呤（MTX）用药后血药浓度监测的临床意义。

OBJECTIVE To study the clinical significance of monitoring the serum methotrexate concentration ( MTX ) after administration with high dose MTX .

目的分析带肾存活5a以上肾移植患者环孢素（CsA）血药浓度监测的临床意义。

AIM To explore the blood concentration monitoring of ciclosporin ( CsA ) in renal transplantation recipient with functional renal allograft more than 5 a.

方法：采用稽延症状自评量表，SAS焦虑自评量表，不良反应监测表，苯妥英钠血药浓度监测等手段，对我所在院病人进行临床观察和实验研究。

Methods : Through the self-evaluate list of protracted symptom ; SAS ; drug reactions monitor list and blood solubility monitor , to observe and investigate the patients in our center .

结论大剂量MTX化疗时，有必要进行血药浓度监测，以制定个体化给药方案，从而将MTX剂量增至患儿可耐受剂量。

CONCLUSION It 's necessary to determine individual remedy by serum concentration monitoring for adding MTX dosage to the extent that can be tolerated by ALL children .

环孢素A（CyclosporineA，CsA）是移植术后常用的免疫抑制剂，由于其治疗指数低，临床应用时要求进行血药浓度监测。

Cyclosporine A ( CsA ) has been the mainstay of immunosuppressive therapy for more than 20 years , as a drug with a low therapeutic index , requires individualized monitoring of blood concentration .

结论HPLC-ECD测定血浆丙泊酚浓度，方法较简便、准确，灵敏度高，重现性好，适用于临床丙泊酚血药浓度监测及药动学研究。

CONCLUSION HPLC-ECD is rapid , simple , accurate and sensitive to determine propofol concentration in plasma . It is suitable for monitoring propofol and pharmacokinetic study .

结论：CDGX>2.4ng·ml-1是多种因素共同影响的结果，包括合并用药、肾功能损害等因素，对地高辛中毒的诊断应将血药浓度监测结果与临床症状相结合。

Conclusion : CDGX > 2.4 ng · ml-1 is a common result induced by multi-factors including in combination with medications , kidney injury , and so on . The diagnosis of digoxin toxication should be made by the results of blood concentration monitoring in combination with the clinical symptoms .

癫痫患儿使用丙戊酸钠缓释片时的血药浓度监测

The Blood Drug Concentration Monitoring of Sustained-Release Valproate in Epileptic Children

重症肌无力患者吗替麦考酚酯的血药浓度监测

Therapeutic Drug Monitoring of Mycophenolate Mofetic in Patients of Myasthenia Gravis

4种治疗药物血药浓度监测结果回顾性分析

Four Kinds of Drugs Were Analyzed Retrospectively Drug Concentration Monitoring Results

68例肾移植受者环孢素血药浓度监测

Monitoring of Cyclosporine A Blood Concentration in 68 Renal Transplant Recipients

1995～2000年度我院地高辛血药浓度监测情况分析

Analysis of digoxin blood concentrations of patients from 1995 to 2000

血药浓度监测对临床用药有指导意义。

To monitor serum drug level is meaningful to clinical medication .