酶的抑制

5种喹诺酮抗菌药对金葡菌DNA螺旋酶的抑制作用

Inhibitory effect of 5 quinolones on DNA gyrase from Staphylococcus aureus

ADP-核糖基转移酶的抑制对γ线所致肿瘤细胞DNA损伤的加强作用

Enhancement of THE DNA Damage in γ - RAY Irradiated Tumor Cells by Inhibition of ADP-Ribose Transferase

该方法有望成为Dam甲基化酶的抑制、激活因子的高通量筛选方法。

It has the potential for the application of screening the inhibitor or activator of Dam methylase .

表明单诺沙星对DNA旋转酶的抑制是PAE产生的机制之一。

The results indicated that the danofloxacin inhibited the DNA gyrase mainly .

氯仿－乙醇混合液（2∶3／v∶v）对该酶的抑制属于非竞争性抑制。

The inhibition of the mixture of chloroform-enthanol ( 2 ∶ 3v / v ) on this enzyme is noncompetitive .

多羟基芳香族化合物对HIV-1整合酶的抑制作用多羟基黄酮醇类化合物的合成

Studies on the inhibition of polyhydroxylated aromatic compounds against HIV-1 integrase

BacillussubtilisB1发酵大豆对血管紧张素转换酶的抑制作用

Angiotensin I-converting enzyme inhibitory activities of fermented soybeans started with Bacillus Subtilis B1

结果几种不同脱钙方法中，10%EDTA+ATM溶液对骨组织切片细胞内RNA酶的抑制效果最好，胶原蛋白Ⅱ原位杂交表达效果最强。

Results The best decalcification method is the 10 % EDTA + ATM solution between the several different decalcification methods .

吴茱萸次碱在人肝微粒体中对细胞色素P450酶的抑制作用

Inhibitory effect of rutaecarpine on cytochrome P450s in human liver microsome

结果表明（1）棉酚对精于ATP酶的抑制作用是依赖浓度的变化；

The results showed that ( 1 ) the inhibitory action of gossypol on sperm ATPase is concentration-dependent ;

复合核苷氧钒配合物（VRC）的合成及对RNA酶的抑制效应

Synthesis of vanadyl-ribonucleoside complexes ( VRC ) and their inhibition on ribonuclease activity

青蒿琥酯钠对体外大鼠红细胞膜钠-钾交换ATP酶的抑制

Inhibition of sodium artesunate on rat erythrocyte membrane Na ( + ) - K ( + ) - exchanging ATPase in vitro

用双倒数作图法确定Pb（NO3）2对该酶的抑制类型。

The inhibition type of Pb ( NO_3 ) _2 on PLAP was determined by using the double reciprocal plot .

Hcy导致的钠、钾2ATP酶的抑制可能与抑郁有关。

Hcy leads to inhibition of sodium and potassium ATP enzyme and may be related to depression .

棉酚对海胆精子鞭毛轴丝及力蛋白（Dynein）ATP酶的抑制作用

The inhibitory effect of gossypol on the sperm flagella axonemal and dynein ATPase in sea urchin

另外，通过抑制曲线分析，发现CarE和GST对甲胺磷的敏感性不同，甲胺磷对这两种酶的抑制程度存在很大差异。

Analysis of inhibition curves indicated that CarE and GST differed in sensitivity to methamidophos . A large difference was observed in the inhibition by methamidophos of these two enzymes .

动力学研究表明，在不同Na~+、K+浓度对，GM3对Na~+、K~+-ATP酶的抑制作用，均呈非竞争性抑制。

Kinetics studies of Na + , K + - ATPase showed that GM3 acted as a non-competitive inhibitor when the concentrations of Na + , K + and ATP changed .

慢性肾衰患者血清中分子物质浓度变化及其对Na，K-ATP酶的抑制作用

Concentration Variation of Middle Molecules in Sera of Chronic Renal Failure Patients and Inhibition for Na , K-ATPase

醋酸酐对太平洋白对虾（Penaeusvannamei）β-N-乙酰-D-氨基葡萄糖苷酶的抑制动力学（英文）

Inhibition Kinetics of Acetic Anhydride on Enzyme Activity of β - N-Acetyl-D-glucosaminidase from Pacific White Shrimp ( Penaeus vannamei )

测定乙醇对酶的抑制动力学，表明乙醇对青蟹碱性磷酸酶的抑制作用是反竞争性机制，其抑制常数Ki为11.8%。

The inhibition of ethanol on the enzyme is found to be uncompetitive type and its inhibition constant is found to be 11.8 % .

ROS的毒性作用包括脂质过氧化物（Lipidperoxidation）的形成，线粒体呼吸链酶的抑制，膜Na~+-K~+-ATPase的抑制，以及其它蛋白的氧化修饰作用。

These include initiation of lipid peroxidation , inhibition of mitochondrial respiratory chain enzymes , inactivation of membrane Na + - K + - ATPase activity , and other oxidative modifications of proteins .

MMS对质膜Ca~（2+）-ATP酶的抑制作用可能是MMS导致细胞病理变化的一个重要环节。

The results suggest that the inhibitory effect of MMS on the Ca2 + - ATPase activity in cell membrane may play an important role in cell pathological changes .

灰树花胞外多糖主要成分GFP-1对α-葡萄糖苷酶的抑制作用

GFP-1 , exo-polysaccharide from Grifola frondosa , inhibits α - glucosidase

这种抑制主要是由于GS蛋白受到抑制，也在较小程度上由于信息通路的腺苷酸环化酶的抑制。因为该种酶能通过对百日咳毒素敏感的G蛋白转导βAR的激动。

The inhibition of the β - AR activation is due to inhibition of Gs-protein and to a lesser extent the adenylyl cyclase of the signaling pathway mediating β - AR stimulation by a pertussis sensitive G-protein that mediates κ - OR activation .

目的：研究蒺藜皂苷（STT）对大鼠小肠α-葡萄糖苷酶的抑制作用及对餐后血糖水平的影响。

Objective : To determine the effects of saponins from Tribulus terrestris ( STT ) on small intestinal α - glucosidase and postprandial blood glucose levels in rats .

结论：STT抑制大鼠餐后血糖水平的升高，是由其对小肠α-葡萄糖苷酶的抑制作用实现的。

Conclusion : It was through inhibiting the activity of α - glucosidase in small intestines that STT significantly retarded the increase in postprandial blood glucose levels in rats .

上述结果表明，RHP对胰腺五种酶的抑制作用，可能是大黄治疗急性胰腺炎作用的生化机制之一，预示RHP在临床上将有重要应用前景。

It is suggested that the inhibitory effects of RHP on five pancreatic enzymes is perhaps one of the biochemical mechanism of Rhubarb on treating the acute pancreatitis .

目的获得特异性的哇巴因结合肽（OCP），拮抗或阻断哇巴因（EO）对Na+、K+ATP酶的抑制作用，为高血压的治疗提供理论和实验依据。

Objective To obtain ouabain conjugated peptides ( OCP ) for blockage or antagonist actions of endogenous ouabain ( EO ) on sodium pump , so as to provide theoretical and experimental bases for hypertension therapy .

联合固氮菌Enterobactergergoviae57-7泌铵突变株的分离和特性氯唑西林对阴沟杆菌β-内酰胺酶的抑制及其与头孢他啶的协同抗菌作用

ISOLATION AND CHARACTERIZATION OF NH ~ ( + _ ( 4 )) EXCRETING MUTANTS OF ENTEROBACTER GERGOVIAE 57 7 Inhibitory effect of cloxacillin on β lactamases from ceftazidime resistant Enterobacter cloacae and its synergistic antibacterial action combined with ceftazidime

方法：以C18反相柱层析和高效液相色谱法从大豆胚轴分离大豆皂苷，比色法测定大豆皂苷单体对α葡萄糖苷酶的抑制活性。

Methods : Soyasaponins were isolated by ODS column chromatography and high-performance liquid chromatography ( HPLC ) from hypocotyls of soybean . The inhibitory activities of each component of soyasaponins against α - glucosidase were tested by colorimetric method .