6-apa

Full-scale Experimental Research on 6-APA Wastewater Treatment

6-APA生产废水处理的生产性试验研究

6-APA is widely used as the material of semi-synthetic penicillin .

6-APA被广泛用作半合成青霉素的前体。

The quality of 6-APA was insured by selecting right dissolvant system and controlling pH value .

选择了合适的溶媒体系及控制pH值以确保6-APA的质量；

Determination of Residue Solvent Content in 6-APA Raw Material by GC with Static Head-space Injection

气相顶空色谱法测定原料样6-APA中的残留溶媒

Study on penicillin G hydrolysis to 6-APA in reversed micelles

反胶团酶促水解青霉素G制备6-APA

Modeling of Penicillin G Hydrolysis to 6-APA in an Immobilized Enzyme-ion Exchange System

固定化酶-离子交换组合系统进行青霉素G水解生产6-APA的模型化研究

Commercial Technology for Producing 6-APA via Immobilized Penicillin Amidase

固定化青霉素酰化酶生产6-APA的产业化技术

The Measurement of Solubility And Isoelectric Point of 6-APA

6-APA溶解度和等电点的测定

Penicillin acylase hydrolysis of 6-APA in reversed micelle with ionic liquids

离子液体反胶团中青霉素酰化酶的水解反应特性

The adsorption behavior of6-aminopenicillanic acid ( 6-APA ) on weak basic anion exchange resin IRA67 was studied .

用静态法研究了6-氨基青霉烷酸在弱碱性阴离子交换树脂IRA67上的吸附行为。

How to isolate and purify 6-APA from the direct Pen G cleavage broth is very important in the whole process of the 6-APA production .

从青霉素G的裂解液中提取、分离和纯化6-APA，是整个6-APA生产工艺中极为关键的步骤。

Conclusions The usage of the new immobilized penicillin acylase reactor in the 6-APA production will result in a higher yield of 6-APA and lower loss of immobilized penicillin acylase .

结论6APA生产中使用新的固定化青霉素酰化酶反应器将提高6APA的收率，减少固定化青霉素酰化酶的损耗。

Immobilized penicillin acylase ( IPA ) is capable of catalyzing the hydrolysis of penicillin G to produce 6-APA and has now been widely used in relevant pharmaceutical industry .

固定化青霉素酰化酶能水解青霉素产生6-APA，这一催化过程已在医药工业中广泛应用。

6-aminopenicillanic acid ( 6-APA ) is a precursor for the synthesis of semi-synthetic penicillins and a critical element in the production of semi-synthetic β - lactam antibiotics .

6-氨基青霉烷酸（6-APA）是生产各种半合成青霉素的原料，在半合成抗生素工业中占据着重要地位。

6-aminopenicillanic acid ( 6-APA ) is a key intermediate for production of semi-synthetic β - lactam antibiotics . It is produced industrially at a scale of 10,000 ton / year .

6-氨基青霉烷酸（6-APA）是半合成β-内酰胺抗生素的关键中间体，年产量在10000吨以上，酶法水解青霉素是生产6-APA的重要途经。

Enzymatic hydrolysis of Penicillin G in to 6-APA is the main route for industrial production . The industrial process is that penicillin acylase catalyzes hydrolysis of Pen G to produce 6-APA under pH control .

工业上主要用青霉素酰化酶在控制pH条件下水解青霉素G制备6-APA，但该水解工艺过程需要消耗酸碱、并产生大量废物，增加了环境的负担；

The solubility of phenoxyacetic acid ( PAA ) in water , water-ethanol , water-acetone and the extraction kinetics of 6-aminopenicillanic acid ( 6-APA ) in PAA was measured .

测定了苯乙酸（PAA）在纯水和水乙醇、水丙醇混合溶剂中的溶解度以及6-氨基青霉烷酸（6-APA）在PAA溶剂中的萃取动力学。

In order to increase the formation rate of 6-aminopenicillanic ( 6-APA ), this subject designed a proper nanofiltration membrane concentration progress , the average gram molecule yield of 6-APA has reached 90.18 % , and n-butyl acetate-alcohol crystallization process was developed .

该项目设计了适当的纳滤膜浓缩工艺，以提高6-APA生成率，6-APA成品的平均克分子收率达90.18%；设计了醋酸丁酯-乙醇结晶工艺；

The effects of impurity of penicillin G , acetone and phenoxyacetic acid ( PAA ) on habit of 6-aminopenicillanic acid ( 6-APA ) in the process of its crystallization and the growth of 6-aminopenicillanic acid in the solution of ethanol are studied .

考察了青霉素G，丙酮和苯乙酸（PAA）杂质在6氨基青霉烷酸（6APA）结晶过程中对晶习的影响及其在乙醇溶液中的生长过程。