Capoten

The study of renin sodium profile and Capoten test in renal hypertension

肾素-钠图和开搏通试验在肾性高血压中的应用研究

Objective To learn about the distribution of renin sodium profile in renal hypertension and evaluate the value of Capoten test in screening renal artery stenosis .

目的了解以肾素钠图为基础的肾素分型在肾性高血压中的分布情况，并评估开搏通试验在肾动脉狭窄筛选中的临床价值。

Capoten can be useful in the treatment of congestive heart failure .

卡托普利可能是有用的，在治疗充血性心力衰竭。

An experimental study on the effect of capoten on the vascular proliferation after balloon angioplasty

卡托普利对血管成形术后管壁增生影响的实验研究

Comparing with renal parenchyma hypertension , plasma renin activity increased significantly after Capoten test in renal artery stenosis and serum aldosterone level decreased significantly .

与肾实质疾病患者相比，肾动脉狭窄患者在开搏通试验后血浆肾素活性明显升高，而血清醛固酮显著下降。

In normal renal function group , the sensitivity of capoten test was 100 % , but in renal insufficiency , the sensitivity of the test decreased to 33 % .

在肾功能正常组中开搏通试验的敏感性为100%，随着肾功能下降其敏感性下降至33%。

In the experiment , capoten + simvastatin + high-dose group shows the best effect , means the best effective treatment for hypertension is Chinese and western medicine plus Hypolipidemic medicine .

实验中开博通+辛伐他汀+高剂量组的治疗效果最好，证明用中西药降压的同时进行适当的降脂治疗是最有效的高血压治疗方案。

After treatment with Delayed-release Verapamil and Capoten for 12 weeks , the t-PA activity was increased , PAI-I activity was decreased . Condusion ;

缓释异搏定和开搏通有效降压12周后，t-PA活性升高，PAI-1活性降低。

Compared with normal group , SHR groups have different degrees of increased on LVMI , and the capoten + simvastatin + high-dose group had lowest LVMI among the SHR groups .

与正常组相比，SHR各组LVMI有不同程度的升高，给药组中开博通+辛伐他汀+高剂量组的LVMI最低。