HIRA

Hira Gene and Development : From Yeast to Human

Hira基因与发育：从酵母到人类

The research on Drosophila has indicated hira gene related to sperm nucleus decondensation during fertilization .

在果蝇中的研究已经表明hira基因与精核解凝形成雄性原核有关。

In addition , according to reports on fish sperm , Hira gene may play an important role in the nuclear coacervation solution .

另据报道称Hira基因可能对鱼类精核解凝发挥重要作用。

The effect of overexpression of Hira on embryogenesis of Drosophila melanogaster

Hira基因的过量表达对果蝇早期胚胎发育的影响

This study laid a foundation for Hira gene of Pingxiang red crucian carp on the direction of function research in fish genetic development .

本研究为萍乡红鲫Hira基因在鱼类遗传发育方向的研究打下基础。

The abnormal low expression of HIRA gene in myocardium of the TOF group may participate in the pathogenesis of TOF . 2 .

小结：1.法洛四联症患儿心肌组织中HIRA基因的异常低表达，提示其可能参与了法洛四联症的发病机制。

Mutations of Hir / Hira genes result in very serious defects in normal development not only in yeast but also in advanced eukaryotes .

Hir/Hira基因功能突变对酵母以及高等真核生物的发育都有非常严重的影响。

That is , the elder brother with the most development speed had the strongest CI strength , but their Hira expression level was the lowest .

幼虫发育速度最快的果蝇兄长引起的cI强度最高，但其体内Hira基因表达水平却最低。

Hira Hira-Japanese : the feeling you get when you walk into a dark and decrepit old house in the middle of the night .

日语：深更半夜你走进一所又黑又旧的破屋子里的感觉。

Research show that the Hira gene is related to solution of the condensate about sperm nucleus in silver crucian carp , fruit flies and other organisms .

在对银鲫、果蝇等一些生物的研究中，Hira基因在雌核发育中与精核解凝有关。

The different expression characters of hira gene in these fish species may be related to the different reproduction models . The research on Drosophila has indicated hira gene related to sperm nucleus decondensation during fertilization .

hira基因在两亲缘种成熟卵子受精前后表达情况不同，可能与两种鱼不同的生殖方式有关。

In the tissues of mature fishes , hira mRNA can be detected in ovary and brain . Based on the expression characterization , it may play a definitive role in maintaining the function of ovary and brain .

成鱼组织中，Caghira在卵巢和脑中均有表达，但脑中表达量较弱，说明该基因在维持卵巢和脑组织作用中起一定作用。

The results showed that in Drosophila males with strong CI strength ( progeny had low egg hatch rate ), the Hira expression level was significantly lower than that in males with low CI or the uninfected .

结果发现，在Wolbachia感染能引起强CI表型（后代胚胎孵化率很低）的雄性果蝇中，Hira表达水平显著低于弱CI表型或未感染的雄果蝇。

HIR / HIRA , one of the histone chaperones , encoded by Hir / Hira ( histone regulation ) genes , were initially identified in yeast as negative regulators of histone gene expression .

Hir/Hira基因产物HIR/HIRA为组蛋白的伴侣蛋白，最先作为组蛋白基因表达的一种负调节因子从酵母中被鉴定出来。

In this Friday , Aug.7,2009 photograph , Hira Lal , who has lost the ability to move and hear , lays on a makeshift bed outside his shanty in Bhopal , India .

在这个星期五，2009年8月7日的照片，希拉拉尔，谁失去了行动的能力和听到的，就奠定了他在外面印度博帕尔简陋的简易床铺上。

Therefore , this study in Pingxiang red crucian carp , had a preliminary exploration on genetic constitution and expression of the Hira gene in the triploid fish . It provided reference media for the research in the function of Hira genes .

因此，本研究以萍乡红鲫为材料，对Hira基因在三倍体鱼类中基因构成及表达特征进行了初步探索，为研究该基因在生殖发育过程中的作用打下基础。