aipc

Mechanism of AIPC is research hotspot recently .

AIPC发生的机制是目前研究的热点。

Second-line endocrine therapy was still used in the treatment of second-line endocrine response to AIPC patients .

二线内分泌治疗应用于对二线内分泌治疗仍有反应的AIPC患者。

Objective : To explore the gene expression of androgen receptor ( AR ) in androgen independence prostate cancer ( AIPC ) of chinese .

目的探讨雄激素受体（AR）在国人雄激素非依赖性前列腺癌（AIPC）的表达及其临床意义。

Conclusions Androgen independent LNCaP-AI cell line was an ideal model to study pathogenesis of AIPC and could imitate the process from ADPC to AIPC .

结论激素非依赖性的LNCaP-AI前列腺癌细胞亚系，可以模拟前列腺癌由激素依赖发展为雄激素非依赖的过程，是理想的激素非依赖前列腺癌的细胞模型。

It is confirm that the coregulators of AR are involved in the occurrence and progression of prostate cancer , and enhance the growth of androgen-independent prostate cancer ( AIPC ) .

已证实AR共调节因子参与前列腺癌的发生和发展，并在雄激素非依赖性前列腺癌细胞的增殖中扮演着重要角色。

Objective To explore the expression of steroid receptor coactivator-1 ( SRC-1 ) and nuclear receptor corepressor ( NCoR ) in androgen independent prostate cancer ( AIPC ) and its clinical significance .

目的探讨类固醇受体辅活化子-1（SRC-1）、核受体辅阻遏子（NCoR）在雄激素非依赖性前列腺癌（AIPC）的表达及临床意义。