ccl2

Recombining murine CCL2 into melanoma B-16 cells and identifying their biological activity

重组CCL2小鼠黑色素瘤B-16细胞的建立及生物学活性的鉴定

The expression of OPN and CCL2 was further correlated with lymph node metastasis and depth of invasion .

CCL2和SNCG的异常表达还与肿瘤的浸润深度、淋巴结转移密切相关。

Objective : To clone chemokine CCL2 into murine melanoma B-16 cells and to investigate the relationship between cancer and chemokine .

目的：在小鼠黑色素瘤B-16细胞中克隆表达趋化因子CCL2，以进一步研究趋化因子与肿瘤的关系。

These chemokines , like CCL2 , regulate monocyte migration and their lower availability at the tumor site is likely to decrease the recruitment and accumulation of intra-tumour TAM .

如CCL2，这些趋化因子，调节单核细胞迁移和其在肿瘤部位的可用性较低，可能会减少招聘和瘤内谭积累。

The thermodynamic and kinetic studies have been carried out on the reaction of singlet CCl2 and ozone O3 at 200K - 2000K , using statistic thermodynamics and Eyring transition state theory with Wigner correction on the basis of quantum chemistry .

在量化计算的基础上运用统计热力学和Wigner校正的Eyring过渡态理论研究了不同温度下单重态CCl2和臭氧O3反应的热力学及动力学性质。

In addition , the expression levels of 12 genes were significantly different in the CD34 ~ + HSPCs cultivated in static and stirred systems . With the exception of CCL2 , the rest genes were highly expressed in the CD34 ~ + HSPCs in static culture .

另外，12个基因在不同培养模式中差异表达，只有CCL2在动态培养中高表达，而其余11个基因均在静态培养中高表达。