gtw

Observation of the Micronucleus and Nuclear Damage Induced by GTW in Human Peripheral Lymphocytes at Go Phase

雷公藤多甙诱发人外周血Go期淋巴细胞微核及核损伤的观察

Conclusion : 1.Every-dosage group of GTW cause sperm deformity .

结论1.雷公藤各剂量组均可致精子畸形。

GTW improves the behavioral impairment induced by beta - amyloid protein injected into hippocampus

雷公藤多甙对大鼠海马内注射Aβ所致学习记忆障碍的改善作用

Methods Male rats were fed with GTW 30mg / d , 30d .

方法：用GTW30mg/d灌喂SD雄性大鼠30d，然后用补肾毓麟汤及氯米芬分别治疗30d，在光、电镜下观察曲细精管中生精上皮的变化。

There are no significant differences between regular doses and a double dose of GTW with improving TCM symptoms .

常规剂量和双倍剂量雷公藤多苷片在改善中医症状方面无显著差异。

The grazing coefficient of the GTW bait for farmland rats was 0 26 .

适口性测定结果表明，黄毛鼠对雷公藤多甙混合剂摄食系数为0.26。

In the last phase , insert the optimal amount of idle time into the sequence scheduled on each machine using improved GTW algorithm .

最后采用改进的GTW算法对各机器上的工件调度插入适当的空闲时间。

Resistant effect of water decoction of root of Crataegus cuneata on male infertility induced by GTW in rats

野山楂根拮抗雷公藤多苷对雄性大鼠生殖损伤作用的研究

Effects of Bu Shen Huo Xue on Ovarian Granulose Cell Apoptosis of DOS Rats Induced by GTW

补肾活血中药对雷公藤致卵巢储备下降大鼠颗粒细胞凋亡的影响

This paper adopts the most scholars by the use of the GTW ( 1995 ) method , and the traditional GTW methods were partially improved .

在对我国创业板市场投资者惯性反向交易策略的研究上，本文采用了大多数学者所使用的GTW（1995）方法，并将传统的GTW方法进行了部分改良。

The influence of Tripterygium wilfordii Hook ( GTW ) on the immunological function in rat 's thymus was studied .

本文报告雷公藤多甙（GTW）对大鼠胸腺免疫功能的影响。

The analgesic ED50 of GCS , GTW and SIN were assayed by mice writhing test ;

利用扭体法测定GCS、GTW和SIN的镇痛ED（50）；

GTW with the dosage of 30mg / kg / d for 10 weeks is advised to establish female mice model of low reproductive function .

建议用雷公藤多甙30mg／kg／d给药10周以建立雌性小鼠肾虚生殖功能低下模型。

Conclusion : After cerebral ischemic-reperfusion injury , the synthesis and secret of TNF - α were increased . GTW could reduce serum TNF - α level .

结论：大鼠脑缺血再灌注损伤后，TNF-α合成、分泌增加，GTW能降低血清中TNF-α含量。

Conclusions : GTW 's antifertility effects include the influences on the spermatids and the testis ' interstitial cells and so on .

结论：雷公藤多甙的雄性抗生育作用对精子细胞及睾丸间质细胞等有影响。

The present study reported the effect of two male antifertility agents gossypol acetic acid and GTW on DNA of C3H10T1 / 2 mouse fibroblasts .

本文报道用原位缺口翻译法，研究男用节育药醋酸棉酚和雷公藤总甙（GTW）对C3H-10T1/2小鼠成纤维细胞DNA的作用。

Conclusion Aggregated A β 1-40 injected into hippocampus can impair the rat spatial memory capacity , and GTW can improve memory disorder induced by A β .

结论将凝聚态Aβ1-40注射入大鼠海马后，可导致学习记忆行为障碍，雷公藤多甙对Aβ所致的行为学损害有改善作用。

Result : Compared with those in GTW model group , the embryo numbers , the relative weight of testis and epididymis and sperm counts and motility in C.

结果：与雷公藤多苷模型组比较，野山楂根组交配雌鼠妊娠胎数、雄鼠睾丸、附睾脏器指数以及附睾精子计数、活力均有提高（P<0.05）；

In this study the human peripheral lymphocytes at Go phase were treated with various doses of GTW , the frequency of micronucleus and nuclear damage were observed after 18h culture .

本实验应用不同剂量的雷公藤多甙处理人外周血Go期淋巴细胞，放置18小时后，直接观察微核率及核损伤的变化。

E_2 level of group A and B was decreased ( with P < 0.05 ) . P level and ovary index of all GTW groups were not decreased at 10 weeks .

A、B组E2水平降低（P＜0.05），各组P水平和卵巢指数无明显变化。

In a colony-forming test , we found that the cells lost their proliferate ability , since no colonies could be formed , if gossypol or GTW were of high concentration ;

与原位缺口翻译实验相对应，集落形成试验表明，在高浓度醋酸棉酚或GTW作用下，细胞失去繁殖的能力；

In this article , we reviewed the progress in researches on influences of GTW to procreation system and the differences in these studies . It is expected to provide instruction for clinical and experimental studies of GTW .

本文主要从GTW的生殖抑制作用研究概况，及研究中存在的分歧等方面进行综述，以期为GTW的进一步药理研究及临床应用提供参考。

Objective To explore the effects of multi-glycosides of Tripterygium wilfordii Hook F ( GTW ) on the changes of learning and memory induced by beta-amyloid protein ( A β) injected into hippocampus .

目的探讨雷公藤多甙对大鼠海马内注射β-淀粉样蛋白（Aβ）后学习记忆行为改变的影响。

By the detection of histology and apoptosis we found a significant dosage-dependent decrease in the total number of germ cells in seminiferous tubules after the GTW treatment , and apoptotic cells were correspondingly increased from low-dosage to high-dosage group .

通过组织学和细胞凋亡的检测我们发现GTW处理后的雄鼠生精小管中生殖细胞总数随着药物剂量的增加而显著减少，而细胞凋亡率显著增加。

It was shown that the length and the weight of kidney were markedly decreased in the rats treated with GTW . The vacuolar degeneration and necrosis in renal tubules and interstitial edema could be dramatically improved in the rats treated with GTW .

结果证实，应用GTW或CsA后大鼠移植肾肾长明显减少，肾重明显减轻，肾小球基底膜增厚，肾小管空泡变性、坏死及间质水肿明显减轻；

Objective To explore the effect of Glycoside of tripterygium wilfordii hook ( GTW ) on the expression of receptor activator of nuclear factor - κ B ligand ( RANKL ) and osteoprotegerin ( OPG ) in the joints of rat adjuvant induced arthritis ( AA ) .

目的探讨雷公藤多苷对佐剂性关节炎大鼠关节中核因子κB受体激活剂配基（RANKL）和护骨素（OPG）表达的影响。