ht4

Objective : To examine the effects of 5 HT4 receptor partial agonist tegaserod on response to rectal distention ( RD ) and on nNOS expression in spinal cord , and to investigate the mechanism of tegaserod influencing visceral sensation .

目的：观察应用5HT4受体部分激动剂替加色罗（tegaserod）对大鼠直肠扩张反应的影响和脊髓神经元性一氧化氮合酶（nNOS）表达的变化，探讨替加色罗对内脏感觉的影响机制。