s1p
- 网络1-磷酸鞘氨醇
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Role of the SPK / S1P signal in the expression of VEGF in human hepatoma cells
SPK/S1P信号途径对人肝癌细胞VEGF表达的作用
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The combined tumorigenic and angiogenic effects of S1P make it an excellent target for anticancer therapy .
其致瘤和促血管生成的双重作用使得S1P成为一个作为抗癌治疗非常好的靶点。
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This article intends to provide a review about the function of S1P in PIRI , based on published data recently .
本文基于近年来的研究进展,对S1P在PIRI中的作用进行综述。
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It is difficult to find an area of physiology and pathophysiology in which S1P does not have important if not key roles .
很难发现生理学和病理生理学领域中S1P不起重要作用,即使不是关键作用。
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Results 1.The effects of SPK1 / S1P signal on survival in human hepatocellular carcinoma MDR cell strain BEL-FU .
结果1.SPK1/S1P信号途径对人肝癌耐药细胞株BEL-FU凋亡的影响。
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S1P has a pivotal role in cell proliferation , migration , apoptosis , and involves in some physiological and pathological progress of cardiovascular system , immune system and et al .
S1P通过调节和参与细胞增殖、迁移、凋亡等机制,参与到生物体内心血管、免疫等系统的诸多重要生理和病理过程。
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S1P improves the increase in the microvessel permeability caused by PAF , which might be mediated by strengthening adherent junction and inhibiting the formation of endothelial gaps .
S1P能改善PAF引起的血管通透性增高,其作用与加强内皮细胞间粘附连接,抑制细胞间隙打开有关。
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Sphingosine kinase ( SPK ) is a key enzyme catalyzing the formation of sphingosine 1 phosphate ( S1P ), which is a lipid messenger with strong angiogenic activity .
细胞内鞘氨醇激酶(SPK)是催化鞘氨醇生成1-磷酸鞘氨醇(S1P)的限速酶。
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Aim : To establish the methods for determining the activity of sphingosine kianse ( SPK ) and the content of sphingosine 1-phosphate ( S1P ) in biological samples .
目的:建立生物样品中鞘氨醇激酶(SPK)活性和1-磷酸鞘氨醇(S1P)含量的测定方法。