ssao

However , it remains unclear whether inhibition of SSAO plays a role in the regulation of myocardial ischemia-reperfusion injury .

然而SSAO在心肌缺血再灌注损伤中是否起作用尚未见报道。

The Toxic Effects of Methylamine Metabolites on the Fibroblasts Mediated by SSAO

SSAO介导的甲胺氧化对大鼠皮肤成纤维细胞的毒性作用

Previous studies have shown that SSAO contributes to the excessive ROS formation in the isolated rat lung with ischemia-reperfusion injury .

有研究表明在离体肺缺血再灌注损伤模型中SSAO参与过多活性氧族的生成。

AIM For further understanding the physiological and pathological significance of plasma semicarbazide-sensitive amine oxidase ( SSAO ) activity and endogenous formaldehyde .

目的进一步了解血浆氨基脲敏感型胺氧化酶（SSAO）活性与内源性甲醛的生理学与病理学意义。

Rats were treated with different drugs , such as selective SSAO inhibitor MDL-72974A and SSAO substrate methylamine .

通过使用SSAO的高选择性抑制剂MDL-72974A以及它的内源性底物甲胺等对动物进行处理，研究血糖与SSAO活性的关系。

Biochemically , SSAO catalyzes the oxidative deamination of primary amines to produce aldehydes , ammonia , and hydrogen peroxide ( RCH2NH2 + O2 + H2O → RCHO + NH3 + H2O2 ) .

生化方面，SSAO催化伯胺的氧化脱胺生成相应的醛、氨和过氧化氢（RCH2NH2+O2+H2O→RCHO+NH3+H2O2）。

In adipocytes and smooth muscle cells , SSAO activity stimulates glucose transport , mimicking the insulin effect , while in endothelial cells , where it is identical to vascular adhesion protein-1 ( VAP-1 ), it is involved in leukocyte trafficking and extravasation during inflammation .

脂肪细胞和平滑肌细胞表达的SSAO酶可促进葡萄糖转运，具有类胰岛素效应；而内皮细胞表达的SSAO酶即血管黏附蛋白-1（VAP-1）参与炎症过程中白细胞的运输与外渗。