克雅氏病

结论脑脊液和血清中s100β蛋白含量检测可以作为克雅氏病诊断指标之一。

Conclusions The content of s100 β protein in CSF and serum could be one of diagnostic indexes of CJD .

在人脑中切断这个基因，也许可能成为克雅氏病（CJD）的一种治疗方法，但是前后两者是不同的。

Switching off the gene in an adult brain , as would have to be done as a treatment for CJD , is a different matter .

目的探讨脑脊液和血清中s100β蛋白含量对克雅氏病的诊断意义。

Objective To explore the significance of detecting s100 β protein in cerebrospinal fluid ( CSF ) and serum in diagnosis of Creutzfeldt-Jakob disease ( CJD ) .

基因噪声抑制技术已经被用于延长被感染羊瘙痒病的老鼠的寿命，这是一种类似痉挛性假性硬化（克雅氏病，CJD）的疾病。

The gene-silencing technique has been used to prolong the lives of mice infected with scrapie , a disease similar to Creutzfeldt-Jakob disease ( CJD ) .

克雅氏病是一种无法治疗的、普遍的、致命的疾病，可由吃了已感染了牛海绵状脑病动物（BSE或疯牛病）身上的各部分而引起。

Creutzfeldt Jakob disease is an untreatable , universally-fatal disease that can be contracted by eating parts of an animal infected with bovine spongiform encephalopathy ( BSE or mad cow disease ) .

方法用固相酶联免疫吸附试验（ELISA）检测13例克雅氏病患者，6例阿尔茨海默病患者和18例无痴呆症状中枢神经系统疾病患者脑脊液和血清中s100β蛋白含量。

Methods The content of s100 β protein in CSF and serum of 13 patients with CJD ( CJD group ), 6 patients with Alzheimer disease ( AD group ) and 18 patients with central nervous system diseases without dementia ( CNS group ) were determined by ELISA .

尽管物种障碍对朊蛋白在物种间传递提供了重要的保护，但是BSE感染的牛导致的人类变异型克雅氏病（vCJD）及BSE疾病的爆发说明朊蛋白对人类具有潜在的影响。

Although the species barrier provided important protection for prion protein pass throuth among species , the outbreak of human variability Creutzfeldt-Jakob disease ( vCJD ) caused by BSE infected cattle confirmed that prion protein possess potential influence for human .

克雅氏病，病毒感染会导致迅速和渐进性痴呆。

Creutzfeldt-Jakob disease , a viral infection leads to rapid and progressive dementia .

克雅氏病通常以个例形式而且在50岁以下的人中偶发。

In its common " sporadic " form , Creutzfeldt & Jakob disease is rare in people under 50 .

事实上没有一个克雅氏病案例与食用养殖鱼类有关，但并不能保证牛的副产品饲养鱼是安全的。

The fact that no cases of Creutzfeldt Jakob disease have been linked to eating farmed fish does not assure that feeding rendered cow parts to fish is safe .