导师刘立新前期研究发现硫代乙酰胺(thioacetamide,TAA)在诱导大鼠肝纤维化的同时伴有IETM,故本研究采用TAA制备大鼠肝纤维化模型。
Mentor Liu Lixin preliminary study found that hepatic fibrosis in rats induced by thioacetamide associated with the intestinal endotoxemia , so we use thioacetamide making the hepatic fibrosis model in rats .