岩藻

细胞生长和表面精蛋白的N－糖链中核心岩藻糖的关系

Relationship between Cell Growth and the Core Fucose in N-glycans of Cell Surface Glycoproteins

唾液酸化Lewisx（sLe~x）是细胞表面岩藻糖化的寡糖。

Sialyl lewis x ( sLe ~ x ) is fucosylated oligosaccharide on the surface of cells .

人α-半乳糖苷酶、α-1,2-岩藻糖转移酶cDNA序列转染克服异种移植超急性排斥反应

Inhibition of Hyperacute Rejection by Transfection of Human α - Galactosidase cDNA and α - 1,2-Fucosyltransferase cDNA

人α1，2岩藻糖苷转移酶（HT）基因转移及其抗异种移植免疫排斥的研究

The Studies of Human α ( 1,2 ) Fucosyltransferase Gene Transferring and Its Function in Rejection of Xenotransplantation

报道了聚丙烯酰凝胶电泳（PAGE）法测定海洋酸性寡糖如卡拉胶、岩藻聚糖硫酸酯及褐藻胶及其衍生物的方法。

The polyacrylamide gel electrophoresis ( PAGE ) analysis method applied to some marine acidic oligosaccharides , such as carrageenan , sulfated fucan , alginate and its derivatives was reported in this paper .

结果表明：岩藻多糖硫酸酯可以通过诱导Hela（？）田胞发生凋亡以及自噬性程序性细胞死亡，来抑制细胞的生长。

The result revealed that fucoidan effectively inhibits the growth of Hela cells by inducing autophagy , as well as apoptosis .

经TLC和高效液相色谱（HPLC）分析金耳胞外多糖由岩藻糖、木糖、鼠李糖、阿拉伯糖、葡萄糖、半乳糖组成。

Its mono-saccharide composition was identified by thin-layer chromatography and HPLC . TEP consists of rhamnose , arabinose , xylose , fucose , glucose , galactose .

形态学研究结果表明，岩藻多糖硫酸酯作用于Hela细胞还可以导致自噬体的形成，这是自噬的一个典型的特征。

In addition , the morphological study indicated a characteristic finding of autophagy , such as the formation of autophagosomes in fucoidan-treated Hela cells .

血清αL岩藻糖苷酶对肝癌的意义

Clinical significance of serum α _L_ fucosidase in liver cancer

岩藻聚糖硫酸酯（Fucoidan）是一种含有硫酸酯的水溶性杂聚糖，是褐藻中特有的一种化学组分。

Fucoidan is a water soluble heteroglycan containing sulfate , which is a special chemical component .

例如岩藻糖基化出现在ABO血型抗原的生成过程中，对人类的生理有重要作用。

For example , fucosylation occurs during the processes of the formation of ABO blood antigens , and they are important for the human physiology .

主要结论如下：1.中分子量岩藻聚糖硫酸酯硫酸根连接在糖的C2或C3位处于平伏键位置，主要含有岩藻糖和半乳糖。

Sulfate connects of medium molecular weight fucoidan is C2 or C3 bit in the equatorial key position and mainly contains fucose and galactose . 2 .

TP及TP-1经酸水解后，表明其单糖组成为甘露糖、葡萄糖醛酸、木糖及少量岩藻糖和葡萄糖。

The TP and TP-1 were composed of mannose , glucuronic acid and xylose , also smal amount of fucose and glucose ;

F-苷肽（Fucoidan-GlycocalyxCompound，F-GC）是从褐藻中提取的一种含硫酸酯基团的蛋白多糖，是磺酸岩藻糖苷多肽的聚合物。

F-GC , extracted from brown algae , is Fucoidan-Glycocalyx Compound which is a kind of proteoglycan with sulfate group .

目的探讨核定位信号肽（NLS）在转人α1,2-岩藻糖苷转移酶（HT）基因小鼠制备中的作用。

Objective To investigate the role of nuclear localization signals ( NLS ) in producing transgenic mice of human α 1 , 2-fucosyltransferase ( HT ) gene .

部分中国人群ABO血型分泌型α（1，2）-岩藻糖转移酶基因（FUT2）多态性研究

Polymorphisms of ABO Blood Group Secretor Type α( 1,2 ) Fucosyltransferase Gene ( FUT2 ) in Partial Chinese Populations

岩藻多糖经盐酸降解4h后，寡岩藻多糖糖的收率达到75%，超过4h寡糖收率开始下降。

However the percentage of fucoidan oligosaccharide output reachs about 75 % with the hydrolysis by HC1 about 4 hours , and the yield decreases after 4 hours .

采用化学发光分析法研究岩藻聚糖硫酸酯清除超氧阴离子自由基（O·-2）及羟基自由基（·OH）的作用，并以高效液相色谱法研究对卵磷脂（PC）过氧化的抑制能力。

The free radical scavenging effects on superoxide anion radicals and hydroxyl radicals of three kinds of sulfated fucans by the chemiluminescence method and the inhibition activity on phosphatidylcholine ( PC ) peroxidation by High Performance Liquid Chromatography ( HPLC ) were studied .

P1由岩藻糖、木糖、甘露糖、葡萄糖和半乳糖构成，摩尔百分比43.4∶33.3∶6.2∶4.3∶12.8；

P1 was composed of fucose , xylose , mannose , glucose , and galactose with a molar percentage ratio of 43.4 ∶ 33.3 ∶ 6.2 ∶ 4.3 ∶ 12.8 ;

联机分析鉴定其结构.得出BJⅡa是多分枝结构的中性杂多糖，其主链是由1→2连接的葡萄糖和岩藻糖构成。

BJ ⅱ a is neutral component with many branches , its ba-sic structure is composed of 1 → 2 linked Glc and Fuc .

研究表明，岩藻多糖的最佳提取温度为100℃，提取时间为6h，加水量为90mL/g，提取率为11.05%；

The result showed that the optimal extracting temperature and time of fucoidin are 100 ? ℃ and 6 ? h , the relative amount of water should be 90 ?

白细胞抑制因子（LIF）对离体小鼠子宫内膜岩藻糖基转移酶（FuT7）表达的影响

Effect of Leukemia Inhibitory Factor ( LIF ) on the Fucosyltransferase VII ( FuT7 ) Expression in Mouse Endometrial Cells in vitro

植物血凝素、刀豆蛋白A、岩藻糖、巯基乙醇及胰酶均致CSH和粘附降低，凝血素增加粘附率。

The chemical agents , such as PHA , ConA , fucose , mercaptoethanol and trypsin decreased CSH and adhesion level of the yeast while lectin increased adhesion level .

P3由岩藻糖、木糖和半乳糖构成，摩尔百分比68.9∶3.7∶27.4。结论P1、P2和P3的单糖含量均以岩藻糖为主，但其他单糖组成有较大差别。

And P3 was composed of fucose , xylose , and galactose with a ratio of 68.9 ∶ 3.7 ∶ 27.4.Conclusion The three polysaccharides are mainly composed of fucose , while the other monosaccharides are very different .

中国人群中α（1,2）岩藻糖基转移酶基因C35T变异的频率研究

Study on the frequency of alpha-1 , 2-fucosyltransferase gene h4 allele ( C35T ) in Chinese population

本实验从广东海域筛选到1株编号为1.1e的产岩藻多糖降解酶的菌株。

In this study , one fucoidanase-producing marine bacterium designated as strain 1.1e was isolated from Guangdong coast .

α-（1，2）岩藻糖转移酶基因（FUT1）多态性及其与猪产仔性状的关联性研究

Research on Polymorphism of α( 1,2 ) Fucosyltransferase ( FUT1 ) Gene and Its Association with Litter Size in Pig

胆管癌胆汁中分离出的3种差异糖蛋白中糖链结构的变化，主要表现为天线数和核心岩藻糖的明显增多，还可能伴有平分型GlcNAc增多。

The increase of antennary and core fucose were the main changes in the sugar chains of these glycoproteins in cholangiocarcinoma bile , and maybe accompanied with with the increase of Bisecting GlcNAc .

海参多糖主要由海参硫酸软骨素（SC-CHS）和海参岩藻聚糖硫酸酯（SC-FUC）2种多糖组成。

There were mainly two kinds of sea cucumber polysaccharides , sea cucumber chondroitin sulfate ( SC-CHS ) and sea cucumber fucoidan ( SC-FUC ) .

岩藻糖化寡糖的合成是由岩藻糖基转移酶（fucosyltranferases，FUTs）催化的。因此，岩藻糖基转移酶的表达可能是这些岩藻糖基化寡糖抗原合成及其表达调控的关键。

The synthesis of fucosylated oligosaccharides is decided by the fucosyltransferases , so the expression of fucosyltransferases might be the key point of the synthesis of oligosaccharide antigens and the regulation of oligosaccharide antigen synthesis .