巯嘌呤

巯嘌呤金属配合物与小牛胸腺DNA的作用

Study on the Mechanism of the Interaction between Mercaptopurine Metal Complexes and Calf Thymus DNA

目的：研究维拉帕米对硫唑嘌呤代谢物6巯嘌呤药动学的影响。

OBJECTIVE : To study effects of verapamil on 6 mercaptopurine pharmacokinetics .

铜（Ⅱ）-巯嘌呤与核酸体系的RRS光谱研究黄素腺嘌呤二核甘酸

Study on resonance rayleigh scattering spectra of Cu (ⅱ) - mercaptopurine and nucleic acid system

目的通过对硫唑嘌呤中间代谢物6-巯基嘌呤（6-mercaptopurine，6-MP）药动学的研究，初步探讨巯嘌呤甲基转移酶（thiopurinemethyltransferase，TPMT）活性对6-MP药动学的影响。

OBJECTIVE To study the influence of thiopurine methyltransferase ( TPMT ) activity on the pharmacokinetics ( PK ) of 6-mercaptopurine , which is the intermediate metabolite of azathioprine .

硫唑嘌呤（AZA）/6-巯嘌呤（6-MP）是治疗炎性肠病（IBD）的重要药物，治疗过程中最严重的不良反应是骨髓抑制。

Azathioprine ( AZA ) and 6-mercaptopurine ( 6-MP ) have a well-established effect as an immunosuppressive agent for inflammatory bowel disease ( IBD ), Myelosuppression is the most serious side effect during treatment .

6-巯嘌呤细胞药理学研究对急性淋巴细胞白血病治疗的指导作用

6-MP intracellular pharmacokinetics study in children with acute lymphoblastic leukemia

稀有金属离子与巯嘌呤血清白蛋白相互作用的研究

Study on Interaction of Rare Metal Ions with Mercaptopurine and Serum Albumin

维拉帕米对硫唑嘌呤代谢物6-巯嘌呤药动学的影响

Effect of verapamil on 6 mercaptopurine pharmacokinetics in rabbits

硫鸟嘌呤核苷酸浓度检测在儿童急性淋巴细胞白血病6-巯嘌呤个体化疗中的意义

Significance of TGNs detection for individualizing 6-MP chemotherapy in children with acute lymphoblastic leukemia

硫唑嘌呤/6-巯嘌呤治疗炎性肠病前检测硫嘌呤甲基转移酶的临床意义

Role of thiopurine methyltransferase measurement prior to treatment of IBD with AZA / 6-MP

巯嘌呤甲基转移酶活性对硫唑嘌呤中间代谢物6-巯基嘌呤药动学的影响

Influence of Thiopurine Methyltransferase Activity on Pharmacokinetics of 6-mercaptopurine , Which is the Intermediate Metabolite of Azathioprine

目的：建立人血浆中硫唑嘌呤中间代谢物6巯嘌呤（6mercaptopurine，6MP）的高效液相色谱测定法。

OBJECTIVE To develop a HPLC assay for the determination of 6-mercaptopurine ( 6-MP ) in human plasma , which is the intermediate metabolite of azathiopurine .

高效液相色谱法分析人血清中硫唑嘌呤和巯嘌呤的浓度系统地研究了高锰酸钾对6巯基嘌呤的氧化作用，提出了高灵敏测定6巯基嘌呤的荧光光度分析新方法。

Determination of Azathiopurine and 6 Mercaptopurine in Serum by Reversed Phase High Performance Liquid Chromatography A new redox reaction spectrofluorimetry for the determination of 6 mercaptopurine ( 6 MP ) in tablets was developed .