微管相关蛋白
- 名microtubule-associated protein
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微管相关蛋白1B在神经发育中的作用
The Role of Microtubule-Associated Protein IB in the Development of Nerveous System
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Tau蛋白是一种微管相关蛋白,主要存在于神经元的轴突和胞浆内。
Tau protein is a microtubule-associated protein , predominantly localized in neuronal axons and cytoplasm .
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禾谷镰孢菌微管相关蛋白基因(map)克隆及其与多菌灵抗药性关系分析
Cloning of microtubule-associated proteins gene ( map ) from Fusarium graminearum and analyzing its relationship with carbendazim-resistance
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2-VO10周大鼠海马微管相关蛋白2的蛋白表达较假手术组降低,差异有统计学意义(P<0.05);
In the 2-VO 4 weeks rats synaptophysin protein levels were down-regulated in the hippocampus compared to the sham operation rats ( P < 0.05 );
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蛋白激酶A催化微管相关蛋白tau磷酸化的研究
Study on the site-specific phosphorylation of tau by PKA
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脊髓压迫伤脊髓前角中微管相关蛋白1B的表达
Expression of microtubule associated protein 1B in ventral horn following spinal cord compression
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不同培养基对海马脑片活性及微管相关蛋白tau表达的影响
Effect of Different Culture Media on Viability and tau Protein Expression in Rat Hippocampal Slices
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V.A.蛋白磷酸酯酶2A调节微管相关蛋白1b的磷酸化
Protein Phosphatase 2A Regulates Phosphorylation of Microtubule-associated Protein 1b
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EGF和bFGF对脐血单个核细胞τ蛋白及微管相关蛋白-2mRNA表达的影响
Effects of EGF and bFGF on expression of microtubule-associated protein tau and MAP-2 mRNA of mononuclear cells derived from human umbilical cord blood
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目的探讨在不同培养基条件下,不同年龄大鼠的海马脑片在长期培养过程中的活性改变及微管相关蛋白tau表达的动态变化。
Objective To explore the effect of different culture media on viability and expression of tau protein in organotypic hippocampal slice .
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目的:观察端侧神经吻合后微管相关蛋白Tau蛋白在背根神经节和神经纤维中的表达特征。
AIM : To observe the expression character of Tau protein in dorsal root ganglia ( DRG ) and nerve fibers .
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rhG-CSF增加实验性脑缺血周围区微管相关蛋白的表达
RhG-CSF enhances expression of microtubule-associated protein 2 in peri-infarct zone after focal cerebral ischemia : An experimental study
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免疫细胞化学染色检测神经微管相关蛋白(MAP2)、乙胆碱酯酶(AchE)和酪氨酸羟化酶(TH)的表达,并计算阳性染色细胞的百分率。
MAP_2 , AchE and TH protein were detected using immunocytochemistry respectively and the percentage of positively stained cells was calculated .
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用新生Wistar大鼠进行脊髓神经元培养,研究微管相关蛋白-5与其单克隆抗体结合后的分布情况。
Monoclonal antibody was used to study the distribution of microtubule associated protein 5 ( MAP5 ) in cultured neurons of the spinal cord of newborn Wistar rats .
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免疫组织化学染色观察培养物微管相关蛋白(MAP-2)。
Immunohistochemical analyses were used to detect the expression of microtubule associated protein-2 ( MAP-2 ) .
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分别用微管相关蛋白2(MAP-2)和肿瘤坏死因子α(TNFα)免疫组化染色测脑梗塞面积和脑TNFα阳性细胞计数。
Use microtubule associated protein 2 ( MAP 2 ) and tumor necrosis factor α( TNF α) immunohistochemistry to measure the cerebral infarct area and TNF α positive cells count .
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目的研究蛋白磷酸酯酶抑制剂冈田酸(OA)对海马神经元微管相关蛋白(Tau)磷酸化的影响,建立Tau过度磷酸化的大鼠模型。
Objective To explore the effect of Okadaic acid ( OA ), a protein phosphatase inhibitor , on Tau hyperphosphorylation and neuronal microtubule system in the rat hippocampus .
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全脑组织微管相关蛋白2a、谷氨酰胺合成酶和CD31的RTPCR产物均在相应位置出现阳性条带,分离纯化的脑微血管仅CD31阳性。
RT-PCR products of microtube-associated protein 2a , glutamine synthetase and CD31 from brain tissue had positive lanes , but only CD31 had positive lanes from isolated microvessels .
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目的探讨持久性大脑中动脉闭塞(MCAO)后丘脑、黑质网状部(SNr)微管相关蛋白2(MAP2)及胶质纤维酸性蛋白(GFAP)的变化。
Objective To investigate the changes of MAP 2 and GFAP of the distal areas after long time middle cerebral artery occlusion ( MCAO ) .
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通过Ⅱ型微管相关蛋白(MAP2)和S100抗体免疫荧光染色鉴定分化的细胞;
The microtubule associate protein ⅱ ( MAP2 ) and S100 immunofluorescence staining was used to detect the differentiated cells .
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目的:探讨新的微管相关蛋白JWA对谷氨酸转运的调控及其机制。
AIM : To explore the mechanism of JWA , a new microtubule-associated proteins , in the regulation of glutamate transport .
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LPS03mg/kg腹腔注射7d龄Wistar大鼠并联合不同时间HI,用微管相关蛋白-2(MAP-2)免疫组化染色测脑梗死面积;
7-day Wistar rats were injected with LPS 0.3 mg / kg combined with different time of hypoxia-ischemia to measure the cerebral infarct area by microtubule-associated protein-2 ( MAP-2 ) immunohistochemistry .
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Tau蛋白是在神经系统发育中具有重要生理作用的人脑内含量最高的微管相关蛋白,其功能异常可引起多种神经系统退行性改变。
Protein tau , one of the major microtubule-associated proteins , plays an important role in the development nerves system . Dysfunction of tau will cause many kinds of neurodegenerative diseases .
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结论JWA蛋白,作为一种新的微管相关蛋白,在微管动力学变化过程和有丝分裂过程中与琢鄄微管蛋白有交互作用,与琢鄄微管蛋白结合,可能对微管稳定性起一定的调节作用。
Conclusion : These results suggest that JWA protein binds to α - tubulin , and might be a novel modulator of microtubule .
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目的:探讨烧伤后慢性应激大鼠海马神经元微管相关蛋白-2(MAP-2)和神经胶质细胞胶质纤维酸性蛋白(GFAP)表达的变化。
Objective : To study the expressions of microtubule associated protein-2 ( MAP-2 ) and glial fibrillary acidic protein ( GFAP ) in hippocampus of rats with depression after burn .
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微管相关蛋白2(Microtubuleassociatedprotein2,MAP2)是调节微管稳定性的磷蛋白,主要分布于神经元的胞体及树突内,被认为是神经元树突较特异的标记物。
Microtubule associated protein 2 ( MAP2 ), a phosphoprotein , can regulate microtubule stability . It is mainly contained in soma and dendrites of neurons and is regarded as a specific marker for dendrites .
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目的探讨微管相关蛋白5(MAP5)与溶酶体之间的相互关系。
Objective To investigate the interrelation between microtubule associated protein 5 and lysosome in cultured spinal neurons .
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目前,DVL-1蛋白对神经细丝磷酸化的影响以及对神经细胞中微管相关蛋白tau磷酸化的影响尚未见报道。
There is no report about the role of DVL-1 in neurofilament phosphorylation , and the role of DVL-1 in tau phosphorylation in neuronal cells is also not known .
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目的:观察缺氧条件下体外培养的心肌细胞微管相关蛋白4(MAP4)的变化与微管变化的关系,以及上调MAP4表达对微管稳定性、细胞活力、凋亡及能量代谢的影响。
Objectives : To determine the effects of microtubule-associated protein 4 ( MAP4 ) on microtubule stabilization of hypoxic cardiomyocytes .
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用免疫组化方法研究了人类新生儿垂体前叶中微管相关蛋白5(Map5)免疫反应神经纤维的形态及分布。
Microtubule-associated protein 5 immunoreactive ( Map 5-ir ) nerve fibers in human neonatal anterior pituitary were studied by immunohistochemistry .