抑制性突触
- 名inhibitory synapse;inhibition synapse
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实验结果提示,腺苷A1受体可能通过介导吸气神经元的抑制性突触输入参与节律性呼吸的调制。
These results indicate that adenosine A1-receptors are possibly involved in the modulation of rhythmical respiration through the inhibitory synaptic input from ⅰ neurons .
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我们发现水杨酸钠在脑片上降低抑制性突触后电流(IPSC)的幅度,同时在培养的海马神经元上直接抑制GABAA受体(GABAAR)介导的反应。
Salicylate significantly inhibited the amplitudes of both evoked and miniature inhibitory postsynaptic currents ( IPSCs ), and directly reduced GABA_A receptor ( GABA_AR ) - mediated responses in cultured rat hippocampal neurons .
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FPI损伤同侧组和对侧组双脉冲易化(PPF)比值和抑制性突触后电位(IPSP)幅值均比对照组显著减小(P<0.05);
The paired-pulse facilitation ( PPF ) ratios of EPSP and the inhibitory postsynaptic potential ( IPSP ) amplitudes were significantly decreased in the FPI-ipsilateral and FPI-contralateral groups , compared with the control group ( P < 0.05 ) .
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这一问题如果放在癫痫病理背景下考虑,变得尤其重要。癫痫发作与抑制性突触传递下降有关,但癫痫发作时CVN的发放行为模式目前尚不知道。
This issue becomes particularly significant if considered under the background of epilepsy or seizures , since little is known about the firing behavior of the CVNs during epileptic attacks , which are well known to be related to decreased function of inhibitory neurotransmission .
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在顶盖区第六层细胞上,记录到自发微抑制性突触后电流(mIPSC)成分,观察到其发放频率明显高于自发微兴奋性突触后电流(mEPSC)的频率。
Whole cell voltage clamp recording of neurons in the sixth layer of optic tectum of slices revealed the higher frequency of spontaneous miniature inhibitory postsynaptic currents ( mIPSC ) than that of spontaneous miniature excitatory postsynaptic currents ( mEPSC ) .
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乙酰胆碱对培养大鼠皮层神经元兴奋性及抑制性突触电流的相反作用
Opposite actions of ACh on excitatory and inhibitory synaptic transmission in cultured rat cortical neurons
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所有的耳蜗核神经元均接受来自兴奋性与抑制性突触的兴奋与抑制性输入。
All CN cells receive a combination of excitatory and inhibitory inputs which form excitatory and inhibitory synapses .
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但是,再灌注7天抑制性突触功能的降低可能是通过突触后的机制实现的。
However , 7 days after ischemia-reperfusion , it is likely that postsynaptic alteration contributes to the reduced inhibition .
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因此,神经元的反应类型被认为是由兴奋性与抑制性突触以不同的权重叠加而造成的。
Therefore , the neuronal response pattern has been thought to be determined by the evoked weight of the excitatory and inhibitory synapses .
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在钳制电压为0毫伏条件下,记录自发的和背根刺激引起的抑制性突触后电流。
At the holding potential of0 mV , spontaneous inhibitory postsynaptic currents ( IPSCs ) and dorsal root stimulation-evoked IPSCs were recorded as outward currents .
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大脑海马组织存在由兴奋性和抑制性突触构成的神经回路,这些神经回路是哺乳动物记忆与学习等高级大脑信息功能实现的基础。
The neuronal circuit of the hippocampus in our brain comprises excitatory and inhibitory synapses , which is related with learning , memory and other high functions in central nervous system .
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结论随着视觉发育,正常大鼠视皮层神经元的γ氨基丁酸受体介导的抑制性突触传递增强,双眼形觉剥夺抑制这一变化,恢复视觉输入后可以逆转。(中华眼科杂志,2005413740)
Conclusion With visual development , the synaptic transmission of visual cortical neurons in normal rats is strengthened , but it can be inhibited by binocular form deprivation and recovered by visual input .
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伴随着触发率传递的,是每层神经元之间的同步。当加入抑制性突触连接时,它与兴奋性突触连接相互抵消,降低了群触发率。
In company with the propagation of the firing rate , synchronization among neurons in the same layer is happened . When the inhibition connection is considered , it offset the excitation input and reduce the firing rate .
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然而,伏核神经元的活动状态不但与其所接受的兴奋性和抑制性突触传递的强度有关,而且很大程度上取决于神经元内源性兴奋性,即神经元膜对外界刺激产生反应的能力。
However , the activity of nucleus accumbens neurons is determinated not only by the strength of excitatory and inhibitory synaptic inputs it receives , but also by the intrinsic excitability of the neuron itself , which means the responsive capability of neuronal membrane to external stimuli .
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非洲爪蟾顶盖神经元的抑制性微突触后电流频率和振幅的电压依赖性
Voltage-dependence of miniature inhibitory postsynaptic current frequency and amplitude in tectal neurons of Xenopus
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结论异氟烷可能通过抑制中枢系统兴奋性氨基酸突触传递增强抑制性氨基酸突触传导而产生麻醉作用。
Conclusions The inhibition of excitatory amino acid synapse transmission and augmentation of inhibitory amino acid synapse transmission may be involved in the mechanism of isoflurane anesthesia .