瑞舒伐他汀

高危患者达到LDL胆固醇、非HDL胆固醇和载脂蛋白B的目标浓度：测定瑞舒伐他汀治疗所致胆固醇有效降低（MERCURY）Ⅱ研究

Achieving LDL cholesterol , non-HDL cholesterol , and apolipoprotein B target levels in high-risk patients : Measuring Effective Reductions in Cholesterol Using Rosuvastatin therapY ( MERCURY ) ⅱ

瑞舒伐他汀能有效降低TC和LDL-C，升高HDL-C水平，虽对apoB和apoA-1无明显影响，但能降低apoB/apoA-1比值。

Rosuvastatin can effectively lower TC and LDL-C , elevated HDL-C levels , can reduce the ratio of apoB / apoA-1 , although had no significant effect on ApoB and apoA-1 .

结果：瑞舒伐他汀钙高、中、低剂量组血清C反应蛋白、白细胞介素-6、肿瘤坏死因子-α及血尿酸水平均明显低于模型组（P0.01）。

Results : The serum C-reactive protein , interleukin-6 , tumor necrosis factor alpha and serum uric acid levels in rosuvastatin calcium groups were lower than those in the model groups ( P 0.01 ) .

瑞舒伐他汀联合氯沙坦组与ox-LDL组、瑞舒伐他汀组、氯沙坦组比较TfmRNA和蛋白的表达减少，差异具有统计学意义（P0.05）。

The rosuvastatin with Losartan group compared with ox-LDL group - 、 rosuvastatin group 、 Losartan group the expression of TF mRNA decreased and this was in a concentration-dependent fashion ( P0.05 ) .

根据ISR的评价标准，结果提示瑞舒伐他汀组未出现再狭窄，对照组出现2例再狭窄，但两组差异无统计学意义（P0.05）。

According to the evaluation criteria of ISR , there is no restenosis in Rosuvastatin treated group , and 2 cases of restenosis in control group , that showed the significant statistically difference ( p0.05 ) .

瑞舒伐他汀具有显著升高冠脉植架后患者血浆APN水平、改善受损的血管内皮功能、抑制平滑肌细胞的过度增殖、抑制血管炎症反应发生。

Rosuvastatin can increase plasma APN level in the patients of coronary stent implantation , improve impaired vascular endothelial function , inhibit the excessive proliferation of smooth muscle cells and vascular inflammatory response . 3 .

瑞舒伐他汀对老年患者颈动脉内膜中层厚度的影响

Effect of Rosuvastatin on Carotid Arterial Intima-media Thickness of Elderly Patients

瑞舒伐他汀对野百合碱所致大鼠肺动脉高压的干预及机制研究

The Evaluation and Mechanism of Rosuvastatin Against Monocrotaline-Induced Pulmonary Hypertensin in Rats

瑞舒伐他汀对大鼠压力超负荷心肌肥厚的影响

Effects of rosuvastatin on the hypertrophic myocardium of pressure-overload rats

探讨瑞舒伐他汀对心肌炎心功能的影响作用。

To investigate the effect of rosuvastatin on cardiac function . 3 .

国产与进口瑞舒伐他汀钙片在健康人体的药代动力学及生物等效性

Pharmacokinetics and bioequivalence of domestic and imported rosuvastatin calcium tablets in healthy volunteers

吡格列酮和瑞舒伐他汀对血脂紊乱兔模型脂代谢及炎症因子的影响

The effect of pioglitazone and rosuvastatin on dyslipidemia rabbits

瑞舒伐他汀治疗原发性高血压患者尿微量白蛋白和动脉粥样硬化

Effect of Rosuvastatin on Microalbuminuria and Arteriosclerosis Plaque of Artery in Hypertensive Patients

瑞舒伐他汀与辛伐他汀治疗高龄患者高血脂的临床疗效比较

Comparison of Clinical Efficacy of Rosuvastatin versus Simvastatin for Hyperlipidemia in Elderly Patients

目的1.评价瑞舒伐他汀对慢性期实验性自身免疫性心肌炎的影响作用。

To assess the effect of rosuvastatin on the chronic phase of EAM . 2 .

瑞舒伐他汀对高血压病合并高脂血症患者超敏C-反应蛋白的影响

The effect of rosuvastatin on C reactive protein in patients with essential hypertension and hyperlipidemia

瑞舒伐他汀对大鼠冠状动脉微栓塞后心肌局部炎症反应及左心室功能的影响

Effect of Rosuvastatin on Myocardial Inflammation and Left Ventricular Disfunction After Coronary Microembolization in Rats

瑞舒伐他汀与阿托伐他汀对急性冠状动脉综合征病人脂蛋白和炎症因子影响

Effects of atorvastatin and rosuvastatin on lipoproteins and inflammation factors in patients with acute coronary syndrome

因此，瑞舒伐他汀钙可在缺血性脑卒中临床二级预防中广泛应用。

So , Rosuvastatin can be used generally in the secondary prevention of cerebral ischemic stroke .

结论：1.阿托伐他汀可以减小斑块体积，而且瑞舒伐他汀减小斑块体积的作用更强。

Conclusions : Atorvastatin decreases plaque volume , and rosuvastatin is more effective compared with atorvastatin .

目的探讨瑞舒伐他汀对慢性肾病患者抗炎疗效。

Objective To explore the anti-inflammatory effect of rosuvastatin on chronic kidney disease ( CKD ) patients .

本研究表明：瑞舒伐他汀对冠脉植架后再狭窄有一定的防治作用。

The study shows that Rosuvastatin can prevent and delay the occurrence of ISR after coronary stent implantation .

初步观察瑞舒伐他汀具有降低冠心病冠脉植架后主要不良心脏事件的作用。

The effect of Rosuvastatin which decreased the rate of adverse cardiac events was initially observed . 4 .

尤其是第三代他汀类药物瑞舒伐他汀在治疗冠状动脉疾病方面表现出非常好的疗效。

In particular , the third-generation statin rosuvastatin elicits good response in therapy for patients with coronary artery disease .

目的：初步探讨瑞舒伐他汀对大鼠颈动脉球囊损伤后新生内膜增生的影响及其作用机制。

In the rat carotid artery injury model , we examined the effects of Dox on neointimal hyperplasia and .

研究丹参素与熊果酸分别对原代肝细胞摄取瑞舒伐他汀的影响。

To explore the the effects of danshensu and ursolic acid on uptake of rosuvastatin in primary hepatocytes . 4 .

瑞舒伐他汀和阿托伐他汀对氯吡格雷抗血小板活性的影响氯吡格雷与他汀类药物的相互作用研究进展

The Influence of Atorvastatin or Rosuvastatin on Antiplatelet Function of Clopidogrel The Research of Co-administration Between the Statins and Clopidogrel

目的：探讨瑞舒伐他汀对高脂血症患者补体、补体调节蛋白及主动脉脉搏波速度的影响。

Objective To investigate the effect of rosuvastatin on complement , complement regulatory proteins and aortic pulse wave velocity in patients with hyperlipidemia .

瑞舒伐他汀除调脂外同时具有抗炎作用，而且抗炎作用与其使用剂量之间存在量-效关系。

Except decrease blood fat , Rosuvastatin also has anti-inflammatory effect . Meanwhile , the anti-inflammatory has a dose-effect relationship with dose . 4 .

瑞舒伐他汀对扩张型心肌病患者心功能及细胞因子的影响牛磺酸对舒张性心力衰竭大鼠心肌细胞钙超载的拮抗作用

Effect of Rosuvastatin on Cardiac Function and Cytokines in Patients with Dilated Cardiomyopathy Antagonism for different doses of taurine on calcium overload in myocardial cells of diastole heart failure rat model