瘢痕疙瘩

目的：观察CO2激光与药物联合治疗瘢痕疙瘩的临床疗效。

To observe the curative effect of CO2 laser and medicine therapy for keloid .

目的研究p53基因第72位密码子多态性与瘢痕疙瘩发病风险的关系。

Objective To investigate the relationship between p53 codon 72 polymorphism and susceptibility to keloid in a southern Chinese population .

自制~（32）P敷贴器治疗瘢痕疙瘩

Treatment of keloid with self-made ~ ( 32 ) P applicator

CO2激光与药物联合治疗瘢痕疙瘩&附30例疗效及随访观察

CO_2 laser and medicine therapy for keloid & clinical observation of 30 cases

CO2激光配合浅部X线治疗瘢痕疙瘩43例

Treatment of Keloid by CO_2 Laser and Soft X-ray : A Report of 43 Cases

RNA干扰对人瘢痕疙瘩成纤维细胞TGF-β1刺激后胶原合成的影响

Impact of RNAi on collagen secretion in human keloid fibroblasts

多重PCR在瘢痕疙瘩Fas基因突变分析中的应用

Multiplex PCR in analysis of Fas gene derived from human keloids

P53蛋白对人瘢痕疙瘩成纤维细胞端粒酶活性的影响

Experimental research of P53 protein effect on telomerase activity in human keloid fibroblasts

瘢痕疙瘩高危个体评估与p53基因第72密码子的多态性

Evaluation of high-risk individuals for keloid and polymorphism of p53 gene codon 72

结论：P53蛋白能够抑制人瘢痕疙瘩成纤维细胞端粒酶活性。

Conclusion : P53 protein significantly inhibits telomerase activity in human keloid fibroblasts .

目的总结YAG激光治疗耳垂瘢痕疙瘩经验。

Objective To summarize the experience for treatment of earlobe scar with YAG-laser .

瘢痕疙瘩及增生性瘢痕Fas蛋白表达的免疫组化分析

Immunohistochemical analysis of Fas protein expression in hypertrophic scar and keloid

用ABC法免疫组化检测瘢痕疙瘩中新合成的胶原。

New formed collagen in keloid was localized with ABC immunohistochemical staining .

fas基因和p53基因在瘢痕疙瘩成纤维细胞中的结构异常与其功能的关系

Abnormal structure of fas and p53 gene in keloid-derived fibroblasts and their function

瘢痕疙瘩家系p53基因的突变

P53 gene mutations in keloid pedigrees

Fas基因转染瘢痕疙瘩成纤维细胞并诱导其凋亡的实验研究

Apoptosis of keloid-derived fibroblasts induced by Fas gene transfection

瘢痕疙瘩周围皮肤成纤维细胞周期分析及P53基因突变检测

Cell cycle analysis and P53 gene mutation detection of fibroblasts derived from the surrounding skin of keloids

瘢痕疙瘩Fas基因外显子6,8,9的突变分析

Study on mutation of exon 6 , 8,9 of Fas gene in human keloids

靶向survivin基因siRNA诱导瘢痕疙瘩成纤维细胞凋亡的实验研究

SiRNA targeted against survivin induces apoptosis of fibroblasts derived from keloid

~（90）Sr敷贴器一次性大剂量治疗瘢痕疙瘩疗效评价

Analyses of therapeutic effect of ~ ( 90 ) Sr contact with one-off large dose

他莫昔芬和腺病毒转染对瘢痕疙瘩成纤维细胞p53表达及细胞周期影响的实验研究

Effects of the Tamoxifen-Treatment and p53 Adenovirus Transfection on the p53 Expression and Cell Cycle in Keloid Fibroblasts

多重PCR-SSCP检测人瘢痕疙瘩Fas基因突变

Detection of Fas gene mutations in human keloids by mPCR-SSCP analysis

5-FU联合激素治疗瘢痕疙瘩的疗效分析

The therapy function of 5-Fu associate with steroid to keloid

瘢痕疙瘩组织中c-myc、ras原癌基因的表达

Expression of C - Myc and Ras Proto - Oncogene in Keloid Tissue

瘢痕疙瘩抑制消减cDNA文库构建和质量分析对筛选和克隆瘢痕疙瘩相关基因的意义

Construction and quality analysis of subtracted cDNA libraries of keloid for the screening and clone of the keloid-related genes

瘢痕疙瘩不同部位成纤维细胞周期蛋白D1的表达

Cyclin D1 expression of fibroblasts in different areas of keloid

携带Fas基因的重组腺病毒治疗瘢痕疙瘩的体外及动物实验研究

Experimental Gene Therapy of Keloid in Vitro and in Vivo Using Recombinant Adenovirus Coding for Fas Gene

Genistein对人瘢痕疙瘩成纤维细胞增殖及侵袭作用的影响

The effects of Genistein on the proliferation and invasion of human keloid fibroblasts

结论瘢痕疙瘩成纤维细胞Fas诱导的凋亡异常，是由于Fas凋亡通路的上游事件无功能Fas蛋白造成，与通路下游无关。

Conclusions The block of apoptotic pathway in keloid is upstream of the pathway - the nonfunction Fas protein .

目的探讨巢蛋白（nestin）在瘢痕疙瘩和增生性瘢痕中的表达。

Objective To investigate the expression of nestin in keloid and hypertrophic scarring .