皮肤毒性

双氯芬酸二乙胺盐凝胶皮肤毒性实验

Experimental Study of Dermal Toxicity from Diclofenac Diethylamine Salt Gel

化妆品安全性评价中皮肤毒性若干替代实验方法的研究

Research for Some Alternative Methods of Dermal Toxicity in Cosmetic Safety Evaluation

目的检测三氯乙烯（TCE）对人表皮角质形成细胞（NHEK）的凋亡诱导作用，探讨TCE皮肤毒性的作用靶。

Objective To investigate the apoptosis-inducing effect of trichloroethylene ( TCE ) on cultured normal human epidermis keratinocytes ( NHEK ) in vitro .

2%黄体酮乳膏的皮肤毒性实验研究

Toxic experimental study of 2 % progesterone cream in the skin

目的对改良五黄油进行皮肤毒性试验。

Objective Study on skin toxicity of modified Wuhuang oil .

目的：研究复方艾叶油乳膏的兔皮肤毒性。

OBJECTIVE : To study the cutaneous toxicity of Compound p-cymene cream .

目的通过临床前毒理学试验方法&皮肤毒性试验和过敏试验，考察烫伤膏的临床应用安全性。

Objective To study the safety of Scald Ointment by skin toxicology test .

近年来临床研究发现，艾滋病合并肿瘤患者放疗后产生的正常组织和皮肤毒性反应明显高于普通肿瘤患者。

Thus , radiotherapy is the mainstay of localized treatment for tumors in AIDS patients .

其负面影响也可能是全方位的，包括哮喘、肺气肿、肺组织纤维化等肺部毒性和心血管毒性、神经毒性、皮肤毒性、胚胎毒性及遗传突变等。

Their negative impact may be comprehensive , including genetic mutations , asthma , cardiovascular toxicity , neurotoxicity , skin toxicity , embryos toxicity , emphysema and lung fibrosis .

本研究进一步探明了三氯乙烯的皮肤毒性机制，也为今后防治三氯乙烯职业损害，开发有效的皮肤防护用品提供了实验依据。

This study partly throw light on the skin toxicity mechanism of TCE , and provide an experimental basis for the prevention and treatment of the skin damage caused by TCE and the development of effective protective gear of skin .

目的观察8-甲氧补骨脂素乳膏对动物皮肤的毒性作用。

Objective : To determine the toxic effect of8-methoxypsoralen cream on skin .

方法①对健康家兔进行皮肤急性毒性试验；

Methods ① Acute dermal toxicity test were conducted in healthy rabbits .

乌头与半夏配伍外用镇痛疗效及皮肤急性毒性研究

Study on Analgesia Action and Acute Dermal Toxicity of Combined Aconite and Pinellia Ternata

目的：考察伤疡愈软膏对动物皮肤的毒性作用。

OBJECTIVE : To study the toxic action of Shangyangyu ointment on animal skin .

目的：研究探讨复方大黄膏对皮肤的毒性作用。

Objective : To investigate the toxic effect of compound Daihuang ointment on cutis .

抗真菌新药特比萘芬对家兔皮肤慢性毒性研究

Chronic toxicity tests of terbinafine on rabbits'derma

目的：研究跌打镇痛液的皮肤急性毒性和皮肤刺激性。

Objective : To study the irritation and acute toxicity of Dieda Zhentong liquid to skin .

染发剂对皮肤的毒性实验

Toxicity Experiment of Skin with Hair-dyes

方法：采用健康家兔进行皮肤急性毒性试验；健康家兔进行皮肤刺激性试验；

Methods : Acute skin toxicity and skin irritation tests were carried out on good health rabbit .

目的观察本草养颜膏对大鼠皮肤的毒性作用。

Objective To observe the toxicity effects of herbaceous beauty parlour cream on the skin of rats .

方法对家兔进行皮肤急性毒性实验、皮肤刺激性实验；对豚鼠进行皮肤变态反应实验。

Methods Acute dermal toxicity test and dermal irritation test were conducted in rabbits , and dermal sensitivity test was performed in guinea pigs .

万古霉素治疗84例革兰阳性球菌感染的效果与肾毒性评价乌头与半夏配伍外用镇痛疗效及皮肤急性毒性研究

Efficacy and nephrotoxicity of vancomycin in the treatment of Gram positive infections Study on Analgesia Action and Acute Dermal Toxicity of Combined Aconite and Pinellia Ternata

目的对肤康涂膜剂进行了部分动物实验研究，包括皮肤急性毒性试验、过敏皮肤性试验，以了解其安全性。

OBJECTIVE The partial animal experiments on Fukang paints have been done , including tests of acute cutaneous toxicity and skin allergy reaction for understanding safety .

方法：皮肤急性毒性试验，皮肤长期毒性试验，皮肤刺激性试验，皮肤过敏试验。

Methods : The toxicity was observed in the acute toxicity test , the long-term toxicity test , the dermal irritation test and the dermal allergy test .

同时选择豚鼠及家兔分别进行烧伤酊的皮肤急性毒性试验，皮肤长期毒性试验，皮肤刺激试验及皮肤过敏试验。

Meanwhile guinea pigs and rabbits were selected separately to carry out skin acute toxicity test and long term toxicity test , skin stimulative test and allergic test .

通过对动物的皮肤急性毒性试验、皮肤刺激性试验及皮肤过敏性试验观察复方米诺地尔的安全性，为临床用药提供依据。

We study the security of the combination of ginseng extract and minoxidil with acute toxicity trial , stimulation trial and hypersensitivity trial on animal skins which provide the foundation for clinical application .

方法应用豚鼠皮肤急性毒性、刺激性、过敏性实验、家兔角膜刺激实验和人体激发斑贴实验，对消粉刺美容皂进行安全性评价。

Methods The safety of anti acne cosmetic soap was evaluated by acute toxicity test , irritation test and allergic reaction on the skin of guinea pigs , by irritation experiments on eyes of rabbit and provocative patch test on human body .

[方法]根据《中药新药研究指南（药学、药理学、毒理学）》提供的方法进行小鼠经口急性毒性试验、大鼠经皮急性毒性试验及家兔完整和破损皮肤急性毒性试验。

Method : acute oral , acute dermal toxicity test and acute skin integrity and damage toxicity tests were carried out on mice , rats , and rabbits respectively , based on the Guidelines for Research of New Drugs of Traditional Chinese Medicine .

方法利用2%戊二醛、0.2%过氧乙酸、2%过氧乙酸、0.2%次氯酸钠对豚鼠进行人为皮肤破损毒性实验，观察豚鼠全身中毒表现和死亡情况。

Methods Carries on the artificial skin breakage toxicity experiment using 2 % glutaraldehyde , 0.2 % and 2 % peracetic acid and 0.2 % sodium hypochlorite were applied to skin shaving wound in guinea pigs , and toxic changes and death of the animals were observed .

结论颈淋巴结N分期、上颈部照射剂量与发生上颈部皮肤急性放射毒性、放射性舌下神经损伤有关。

Conclusion N staging , total dose of external radiation for superior neck and acute radiation-related dermatitis of superior neck were relevant with radiation-induced hypoglossal nerve palsy in patients with nasopharyngeal carcinoma .