硫氧还蛋白

硫氧还蛋白（Trx）是一种广泛表达于多种生物的小分子蛋白质。

Thioredoxin ( Trx ) is a kind of small molecule protein which is expressed in various organisms .

心肌缺血性损伤与硫氧还蛋白系统

Myocardial Ischemia Injury and Thioredoxin System

其它含硒蛋白（如硒蛋白P和硫氧还蛋白还原酶）也具有抗氧化特性。

Moreover , other selenoproteins ( e.g. selenoprotein P and thioredoxin reductase ) also have been shown to possess antioxidant properties .

H2O2诱导的线粒体损伤神经元内硫氧还蛋白mRNA水平的变化

Changes of thioredoxin mRNA level in neurons with mitochondrial dysfunction insulted by h_2o_2

人硫氧还蛋白还原酶cDNA的克隆及在大肠杆菌中的表达

Cloning of Human Thioredoxin Reductase cDNA and Its Expression in E. coli

人硫氧还蛋白cDNA的克隆及序列测定

Cloning and sequencing of the cDNA for human thioredoxin

血吸虫硫氧还蛋白免疫原性研究Ⅱ日本血吸虫硫氧还蛋白DNA疫苗小鼠保护性免疫研究

Studies on immunogenicity of Schistosoma thioredoxin ⅱ . Study on protective effect of Schistosoma japonicum thioredoxin DNA vaccine against challenging infection in mice

I亚基是硫氧还蛋白的靶蛋白，其ATP酶活性受到叶绿体氧化还原状态的调控。

ChlI is a target protein of thioredoxin-f , which redox regulates ATPase activity of ChlI in chloroplast .

在乳腺癌细胞MCF-7中紫杉醇诱导硫氧还蛋白结合蛋白-2的表达

Expression of Paclitaxel Inducing TRX-Binding Protein-2 in MCF-7 Cells

柯萨奇B3病毒感染小鼠心肌硫氧还蛋白的表达

Thioredoxin expression in myocardium of mice infected by Coxsackie virus B3

目的利用硫氧还蛋白融合表达系统表达小鼠内皮抑素（endostatin）。

[ Objective ] To express mouse endostatin by using thioredoxin fusion expression system .

硫氧还蛋白Thioredoxin（Trx）是一类高度保守的低分子量蛋白质。

Thioredoxin ( Trx ) is a small and conservative protein .

硫氧还蛋白（Thioredoxin，TRX）是一个分布广泛的氧化还原蛋白。

Thioredoxin ( TRX ) is a widely distributed redox protein .

序列分析表明，克隆所得序列与GenBank中大鼠硫氧还蛋白cDNA序列完全一致。

Sequence analysis verified that the sequence of the cloned cDNA is identical to that of rat TRX cDNA in Genbank .

大肠杆菌硫氧还蛋白thioredoxin基因的克隆及表达

Cloning and Expression of Escherichia coli Thioredoxin

目的：探讨大鼠脊髓损伤模型中硫氧还蛋白还原酶（Thioredoxinreductase，TR）的动态表达及其作用。

Objective To study the expression and role of thioredoxin reductase ( TR ) in spinal cord injury model in rats .

反义TrxS基因对转基因小麦籽粒硫氧还蛋白还原活性的影响

Effect of Anti-TRX s Gene on Thioredoxin Reduction Characteristics in Seeds of Transgenic Wheat

灯盏花素对UL补硒大鼠谷胱甘肽过氧化物酶和硫氧还蛋白还原酶基因表达和活性的影响

Effects of Scutellarin on glutathione peroxidase and thioredoxin reductase gene expression and activities in rats supplemented with upper limit Selenium

拟南芥硫氧还蛋白M1型基因（AtTRXm1）与环境逆境之间的关系

The Relationship of Arabidopsis thaliana Thioredoxin M-type 1 ( AtTRX m1 ) Gene with Environmental Stress

人脑硫氧还蛋白还原酶的光谱学研究目的：克隆人硫氧还蛋白还原酶（TR）基因并构建原核表达载体，获得TR蛋白。

Spectroscopy Study on Thioredoxin Reductase From Human Brain Objective : To clone thioredoxin reductase ( TR ) gene and express in E. coli .

利用此表达系统成功地获得的hG－CSF－硫氧还蛋白融合蛋白的高效可溶性表达，表达水平达总细胞可溶蛋白的41%以上。

Using this system , hG CSF was succesfully expressed to a level of more than 41 % of total cellular proteins in complete soluble form as thioredoxin fusion .

硫氧还蛋白具有保护多巴胺能神经元免受MPTP所致内质网应激损伤，然而这一作用的分子机理还不十分清楚。

Trx protects neuron from ER stress-mediated cytotoxicity induced by MPTP , and the molecular mechanism is still unclear .

对点杂交筛选所得到的15个克隆中的4个进行Northern了分析，有两个确证为差异表达的基因，测序结果表明它们分别推测为编码硫氧还蛋白和亮氨酸重复类蛋白的基因。

Four out of the total 15 clones were analyzed by Northern blot Two of them were confirmed expressed differentially . Sequencing of the two clones showed that the two genes encode thioredoxin and leucine-rich repeat protein respectively .

对转基因大麦籽粒进行了初步的生化分析，结果显示转基因大麦籽粒中硫氧还蛋白h的活性是非转基因籽粒的3.3倍；

Moreover , biochemistry analyses were carried out to discover the effects of trxs gene in transgenic seeds . The results showed that trx h activity in transgenic seeds was 3.3 times as great as that in non-transgenic seeds ;

另一方面，在活体动物实验中，硫氧还蛋白诱导物PTS通过诱导硫氧还蛋白的表达，抑制了炎症反应以及线粒体损伤介导的神经元凋亡。

In vivo , PTS , an inducer of Trx , inhibited the inflammation-or / and mitochondria-mediated neuron apoptosis through up-regulation of Trx .

目的：观察运动对大鼠心肌、骨骼肌硫氧还蛋白还原酶（TR）的影响。

Objective The present study aimed at investigating the influences of exercise on thioredoxin reductase ( TR ) of myocardium and skeletal muscle in rats .

探讨紫杉醇在人乳腺癌细胞株MCF-7中诱导硫氧还蛋白结合蛋白-2表达及与其诱导的相关途径。

The expression of paclitaxel inducing thioredoxin binding protein-2 ( TBP-2 ) and the inducing pathway of TBP-2 in MCF-7 cell are firstly discussed in this paper .

将该短肽的基因插入质粒pET-32a（+），与硫氧还蛋白（Trx）在大肠杆菌BL21（DE3）中融合表达；

The gene of 7-mer peptide was cloned and the expression plasmid pET-32a ( + ) _Trx_RBIP was constructed .

硫氧还蛋白还原酶是一种NADPH依赖的包含FAD结构域的二聚体硒酶，属于吡啶核苷酸-二硫化物氧化还原酶家族成员。它和硫氧还蛋白、NADPH共同构成了硫氧还蛋白系统。

The mammalian thioredoxin reductases are a family of selenium containing pyridine nucleotide-disulphide oxido - reductases which catalyze the NADPH-dependent reduction of the redox protein thioredoxin .

在细胞水平，硫氧还蛋白诱导物GGA可以缓解MPP+引起的内质网应激，从而抑制细胞凋亡。

GGA , an inducer of Trx , inhibited the ER stress induced by MPP + in vitro .