端粒酶

联检端粒酶活性和DNA异倍体诊断恶性腹水

Combined Determination of Telomerase Activity and DNA Aneuploid in Ascites for Diagnosis of Malignant Ascites

应用PCR技术检测肺癌中端粒酶活性

Detection of Telomerase Activity in Lung Cancer by PCR Analysis

食管黏膜脱落细胞DNA倍体和端粒酶活性检测对食管癌诊断的价值

Detection of telomerase activity and DNA ploidy analysis in the diagnosis of esophageal cancer

甲状腺肿瘤端粒酶逆转录酶mRNA的表达

Expression of mRNA of telomerase reverse transcriptase in thyroid neoplasms

DNA去甲基化对肝细胞人端粒酶逆转录酶上调的研究

DNA Demethylation induced by 5 ' - aza-dC Upregulates human telomerase reverse transcriptase in liver cell line SMMC-7721

寻常性银屑病皮损端粒酶RNA、反转录酶mRNA表达

Expression of Telomerase RNA and Telomerase Reverse Transcriptase mRNA in Lesions of Psoriasis Vulgaris

端粒酶RNA基因在白细胞中表达的研究

Study on the Expression of Telomerase RNA in Leukocyte

TRAP聚合酶链反应-酶免疫间接定量法测定鼻咽癌中端粒酶活性

Telomerase Activity in Nasopharyngeal Carcinoma Detected With TRAP PCR ELISA Indirect Quantitative Assay

反义人端粒酶RNA组分基因对胃癌细胞端粒酶活性的影响

Influence of antisense hTR eukaryotic expression vector on telomerase activity in gastric cancer cells

端粒酶RNA反义核酸降低鼻咽癌细胞p53蛋白表达水平

Decreased expression of p53 protein in nasopharyngeal carcinoma cells by telomerase RNA antisense oligodeoxynucleotides

反义人类端粒酶RNA逆转录病毒载体构建及其对结直肠癌细胞的抑制作用

Construction of antisense human telomeric RNA retroviral vector and its inhibition on colorectal cancer cells

端粒酶联合DNA倍体分析对贲门癌的诊断率为95.56%。

The diagnostic accuracy of cardiac cancer was 95.56 % if telomerase activity and DNA analysis were examined at the same time .

端粒酶催化亚单位和p53基因在大肠癌中表达的研究

Big and Good Matter Expression of telomerase reverse transcriptase and p53 oncogene in colorectal cancer

X刀放射对U（251）细胞端粒酶活性影响的实验研究

Experimental study on the activity of telomerase of U_ ( 251 ) gliomas cells treated by X knife

用端粒重复序列扩增法（TRAP）测定上述组织标本中的端粒酶活性。

Telomerase activity was examined in these samples with telomeric repeat amplification protocol ( TRAP ) .

端粒酶活化不参与调控bcl-2蛋白表达。

Telomerase does not take part in the regulation of the expression of bcl-2 protein .

NSCLC中肝素酶与端粒酶活性表达无相关性（P0.05）。

There was no correlation between heparinase mRNA expression and telomerase expression in NSCLC .

结论：一步RT-PCR是检测端粒酶亚单位的有效方法。

Conclusions : One step RT PCR is a powerful method for detecting telomerase subunits .

蛋白激酶C对鼻咽癌CNE-2Z细胞端粒酶活性的影响

Effect of Protein Kinase C on Telomerase Activity of Nasopharyngeal Carcinoma Cell Line CNE-2Z

端粒酶活性检测联合血清CA（125）检测在卵巢肿瘤诊断中的临床意义

Clinic significance of combined examination of telomerase activity and serum CA_ ( 125 ) in the diagnosis of ovarian tumor

芒果甙对白血病K562细胞端粒酶活性和凋亡的影响

The Effect of Mangiferin on Telomerase Activity and Apoptosis in Leukemic K562 Cells

方法：采用TRAP法检测Hep2细胞在反义核酸处理前后端粒酶活性的变化。

Methods : Telomerase activity of Hep 2 cells with antisense treatment was measured using the TRAP assay .

端粒酶逆转录酶与Bcl-2在口腔黏膜癌变过程中的表达及意义

Expression of human telomerase reverse transcriptase and Bcl-2 in premalignant and malignant lesions of human oral mucosa

端粒末端DNA形成G-四螺旋，能阻止端粒酶发挥功能，抑制端粒酶活性，另外在一些癌基因的启动子区域也可形成G-四螺旋，控制癌基因。

Telomeric DNA formats G-quadruplex , thereby inhibits telomerase activity . Also , formation of G-quadruplex in promoters of several oncogenes can inhibit expression of oncogenes .

高三尖杉酯碱对HL-60细胞端粒酶量的抑制效应

Inhibitory effect of homoharringtonine on telomerase content of HL-60 cells

端粒酶是一种特殊的逆转录酶，它能在体内延伸染色体单链末端，在体外延伸寡聚核苷酸。一般认为端粒酶的蛋白催化亚基和RNA亚基组成了核心酶，它们对体外活性是必需的。

Telomerase is a specialized reverse transcriptase that elongates the single-stranded chromosome ends and oligonucleotides in vivo and in vitro .

结论：硫化砷在诱导HL-60细胞凋亡的同时，下调其端粒酶活性。

CONCLUSION : Arsenic sulfide can inhibit telomerase activity .

二甲基亚砜对HL-60细胞端粒酶活性和细胞周期的影响

Effects of DMSO on Telomerase Activity and Cell Cycle in HL 60 Cell

目的：检测人贲门组织、贲门癌组织和食管组织、食管癌组织端粒酶RNA组分表达及端粒酶活性，探讨其在贲门癌和食管癌中的作用。

Objective : To investigate the association of the telomerase RNA and telomerase activity with carcinoma tissues of cardia and esophagus .

人端粒酶反转录酶siRNA抑制肿瘤细胞端粒酶活性的研究

Inhibition of Telomerase Activity by siRNA Targeted to Human Telomerase Reverse Transcriptase