肌成纤维细胞
- 名myofibroblast
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结论CTGF在体外能刺激肾小管上皮细胞向肌成纤维细胞(MyoF)转分化,而CTGF反义ODN的导入可有效抑制TGF-β1诱导的转分化过程。
Conclusion CTGF can promote the transdifferentiation of human renal tubular epithelial cells towards myofibroblast ( MyoF ) in vitro , and CTGF blockade results in a dramatic inhibition of TGF - β - induced transdifferentiation of renal tubular cells .
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肌成纤维细胞在创伤愈合中的地位和作用
Status and role of myofibroblast in wound healing
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伤口愈合中P物质、降钙素基因相关肽在大鼠肌成纤维细胞分化中的作用
Effect of substance P and calcitionin gene-related peptide on myofibroblast differentiation in wound healing in rat
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采用X射线光电子能谱法(XPS)对材料作表面分析。MTT试验检测种植于材料表面的大鼠肌成纤维细胞的细胞黏附效率。
X-ray photoelectron spectroscopy ( XPS ) was used for surface structure analysis and MTT test was used to examine the efficiency of cell attachment of 4 groups .
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Egr-1影响成纤维细胞增殖、向肌成纤维细胞分化,并且与肺泡上皮细胞、内皮细胞凋亡,肺泡、气道炎症以及细胞外基质形成有关。
Egr-1 is concerned with the apoptosis of alveolar epithelial cell and endothelial cell .
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肝星状细胞(HSC)激活并转化为肌成纤维细胞是肝纤维化发生、发展的核心环节。
The keys of the pathogenesis of liver fibrosis is activation of hepatic stellate cells ( HSC ) and transformation into fibroblast .
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此外肺内上皮细胞(如肺泡Ⅱ型上皮细胞和气道上皮细胞等)可通过上皮-间质转化(epithelial-MesenchymalTransition,EMT)增加肺内肌成纤维细胞的数量。
In addition , pulmonary epithelial cells ( including alveolar II epithelial cells and airway epithelial cells ) could increase the number of myofibroblast through epithelial-mesenchymal transition ( EMT ) .
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给予25mg/kg的牛磺酸可明显降低肝的羟脯氨酸含量及肌成纤维细胞数量,肝切片中胶原的沉积亦明显减轻。
Administration of 25 mg / kg taurine apparently decreased the level of liver hydroxyproline and the number of liver myofibroblasts , and the accumulation of collagens in liver sections also decreased .
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ALI急性期伴随大量炎症因子和促纤维化因子的合成与分泌,诱导肺内成纤维细胞分化成熟为肌成纤维细胞,后者为肺纤维化的主要效应细胞。
During acute inflammatory phase , a large number of inflammatory cytokines and pro-fibrogenic factors were synthesized and secreted . Then intrapulmonary fibroblast matured into myofibroblast , which were the main effector cells of pulmonary fibrosis .
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目前对AAN机制研究表明,AA可致肾小管上皮细胞坏死、凋亡,小管上皮-肌成纤维细胞转分化,AA-DNA加合物形成等。
Studies in mechanisms of AAN showed that AA induced renal tubular necrosis or apoptosis , tubular epithelial-myofibroblast transdifferentiation . AA-DNA adducts formation and so on .
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肌成纤维细胞(Myofibroblast,MF)的产生及其在肾间质中的聚积和随后发生的肾小管萎缩被认为是RIF的核心因素。
Fibrosis of the key cellular muscle into fiber cells ( MF ) generation , and its accumulation in the renal interstitium and subsequent tubular atrophy have been considered a key factor of chronic RIF .
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结果犬股静脉肌成纤维细胞在p(3HB-co-3HH)/PU薄膜涂附的玻片上及其浸提液中均生长良好,皮下植入显示仅引起轻度的炎症反应。
Results The myofibroblasts growed well on the glass slide covered with membrane of p ( 3HB-co-3HH ) / PU and in the solution of p ( 3HB-co-3HH ) / PU . The patches implanted mouse subcutaneous only caused slight inflammation .
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研究证实,多种因素参与肾间质纤维化的过程,其中肌成纤维细胞(myofibroblast,MFB)在肾间质纤维化的启动和发展过程中起着重要的作用。
Modern research has confirmed that many factors participated in the progress of RIF . , among which myofibroblast ( MFB ) plays an important role in the process of priming and developing of RIF .
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目的:研究慢性马兜铃酸肾病(CAAN)大鼠肾小管上皮细胞-肌成纤维细胞转分化(TEMT)与肾间质纤维化之间关系。
Objective : To investigate the relationship between renal tubular epithelial-myofibroblast transdifferentiation ( TEMT ) and renal interstitial fibrosis in the rats with chronic aristolochic acid nephropathy ( CAAN ) .
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目的探讨转化生长因子β-1(TGFβ1)诱导人肾小管上皮-肌成纤维细胞转分化(TEMT)过程中结缔组织生长因子(CTGF)的表达和作用。
[ Objective ] To investigate the expression and effect of connective tissue growth factor ( CTGF ) during the process of human tubular epithelial-myofibroblast transdifferentiation ( TEMT ) induced by transforming growth factor β - 1 ( TGF β 1 ) .
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静脉与动脉内皮细胞和肌成纤维细胞的比较
Comparison of Myofibroblasts and Endothelial Cells from Artery or Vein
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大鼠卵泡膜中肌成纤维细胞的形成及意义
The formation and significance of myofibroblasts in theca layer of rat ovary
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日本血吸虫感染兔肝肌成纤维细胞的动态变化及其意义
Dynamic changes in hepatic myofibroblast of rabbits with schistosoma japonicum
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肌成纤维细胞凋亡与肥厚性瘢痕消退的关系
Relationship between apoptosis of myofibroblasts and regression of hypertrophic scar
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肌成纤维细胞在胆道愈合过程中的表达及意义
The expression and significance of myofibroblast in the healing process of bile duct
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医源性胆管狭窄与肌成纤维细胞的相关性研究
The Pertinency Research of Myofibroblast and Iatrogenic Biliary Stricture
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人脐带结缔组织的肌成纤维细胞
Myofibroblasts in the Connective Tissue of Human Umbilical Cord
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犬股静脉同时获取内皮细胞和肌成纤维细胞的方法研究
Study on Isolation and Culture of Endothelial Cells and Myofibroblasts from Canine Femoral Vein
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维甲酸抑制大鼠单侧输尿管梗阻模型肌成纤维细胞增生
Retinoic acid inhibits renal interstitial myofibroblast proliferation in a rat unilateral ureteral obstruction model
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洛伐他汀对TGF-β诱导的肾小管上皮细胞&肌成纤维细胞转分化的影响
Lovastatin Effects Transdifferentiation of Rat Renal Tubular Epithelial Cell Induced by TGF - β
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肌成纤维细胞是一组平滑肌样成纤维细胞,在正常心脏仅存在于瓣膜组织中。
Myofibroblasts are smooth-muscle-like fibroblasts , and only reside in valve in normal heart .
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肌成纤维细胞功能活跃,持续存在,是导致胆管瘢痕性挛缩的重要原因。
Myofibroblasts are the main cause for scar contracture and stricture of bile duct ;
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不同刚度接骨板内固定后骨改建的组织学观察及组织形态学测量肌成纤维细胞与血管重塑
The Histologic Observation and Histomorphometry of Bone Remodeling after Internal Fixation with Different Stiffness Plates
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小管间质肌成纤维细胞激活对大鼠残余肾硬化的影响
Influence of the activation of tubulo-interstitial myofibroblast on the renal scarring in rat remnant kidney
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人癌间质中肌成纤维细胞的超微结构研究
An-Ultrastructural Study of Myofibroblasts in Carcinoma Stroma