脐带血干细胞

目的：利用人脐带血干细胞（humanumbilicalcordbloodstemcells，HUCBSC）移植治疗兔急性心肌缺血，探索防治缺血性心脏病的新方法。

Objective To investigate a new strategy to acute myocardial ischemia by means of human umbilical cord blood stem cells ( HUCBSC ) transplantation .

人脐带血干细胞移植防治兔急性心肌缺血的实验研究

An experimental study on the transplantation with human umbilical cord blood stem cells in the treatment of acute myocardial ischemia in the rabbit

结果脐带血干细胞在体外诱导分化培养第7天呈现明显树突状分支，并可检测到HLA-DR和CD1a分子的表达。

Results The monocytes from umbilical blood appeared dendritic cells in culture 7 days later and expressed HLA-DR , CD1a marker .

目的：将人类多药耐药基因（mdr1）全长野生型mRNA转导至人脐带血干细胞，分析其P糖蛋白的表达及干细胞的耐药性。

OBJECTIVE : To transfect a full-length mRNA for the human multidrug resistance gene ( mdr1 ) into human umbilical cord blood stem cells and investigate the expression of P-glycoprotein and the resistance to chemotherapy drugs in vitro .

在理论计算中，本文采用细胞脱水、冰晶成核和扩散控制的晶核长大三部分耦合模型来研究脐带血干细胞在DMSO溶液中进行降温和复温过程中胞内冰形成的情况。

In the presence of dimethyl sulfoxide ( DMSO ), a three-part , coupled model cell dehydration , nucleation and crystal growth was used to study intracellular ice formation ( IIP ) in umbilical cord blood during the cooling and warming process .

目的观察人脐带血干细胞（HUCBSC）移植对大鼠急性心肌梗死后左室重构的影响。

Objective To observe the influence of human umbilical cord blood stem cell ( HUCBSC ) transplantation on the left ventricular remodeling of rats after acute myocardial infarction ( AMI ) .

异基因脐带血干细胞移植治疗假肥大型肌营养不良症一例

Allogeneic umbilical cord blood stem cell transplantation in Duchenne muscular dystrophy

脐带血干细胞的基础与应用研究

The research and application of cord blood stem cells

该装置显著增加了可以用于成人移植的脐带血干细胞数量。

This significantly increases the quantity of stem cells that can be transplanted into adults .

为了储存脐带血干细胞，脐带血在婴儿出生后数分钟内被抽取，并迅速由专递员送去处理。

To bank cord stem cells , the cord blood is extracted minutes after the birth of the baby and rushed by courierto be processed .

数千份脐带血干细胞移植被用来治愈患有血液或免疫力疾病的孩子。

Thousands of successful umbilical cord blood stem cell transplants have already been carried out to treat children with severe blood conditions or immune disorders .

在用新的培养液配方进行的实验中，霍普金斯课题组先以脐带血干细胞和可以向干细胞中转化7个基因的质粒为材料进行研究。

In their experiments with the new growth medium , the Hopkins team began with cord blood stem cells and a plasmid to transfer seven genes into the stem cells .

英国邮报称：虽然其它科学家也培育出了肝细胞，但是新城大学小组是第一个利用脐带血干细胞获得一定尺寸肝组织的。

While other scientists have created liver cells , the Newcastle team are the first to create sizeable sections of tissue from stem cells from the umbilical cord , the Daily Mail said .

细胞体外扩增培养情况：应用干细胞因子+白细胞介素3+白细胞介素6+血小板生成素+FLt-3配基这一细胞因子组合，脐带血干细胞可保持>98%的细胞存活率；

Culture of cell amplification in vitro : In the SCF + IL3 + IL6 + TPO + FLt-3 ligandin group , stem cell from cord blood could keep the cell survival rate of > 98 % ;

脐带血造血干细胞逃逸NK细胞杀伤机制的实验研究

Mechanisms of Umbilical Cord Blood Hematopoietic Stem Cells Escaping from NK Cell-mediated Cytotoxicity

细胞因子FL、TPO对脐带血造血干细胞的扩增作用

Effects of cytokine fl , tpo on in vitro expansion of human umbilical cord blood HSC

排除标准：①脐带血造血干细胞。②文献综述，重复研究，Meta分析类文章。

Exclusive criteria : ① Haemopoietic stem cells from umbilical cord blood ② Review , repetitive study or Meta analytical papers .

从血造血干细胞（HSC）来源上可分为骨髓移植（BMT）、外周血造血干细胞移植（PBSCT）、脐带血造血干细胞移植（CBT）。

According to the source of haematopoietic stem cell ( HSC ), its can be divided into the Bone Marrow transplantation ( BMT ), Peripheral blood stem cell to transplantation ( PBSCT ), Cord-blood haematopoietic stem cell transplantation ( CBT ) .

脐带血造血干细胞的采集、浓缩与低温冷冻保存

Collection , processing and cryopreservation of placental cord blood hematopoietic stem cells

脐带血造血干细胞的分离和冷冻保存研究

Separation and cryopreservation of hematopoietic stem cells from umbilical cord blood units

4500份脐带血造血干细胞保存研究

Studies of 4500 Umbilical Cord Blood Units Banking

选择一份或者两份脐血是根据脐带血中干细胞的数目而定。

The choice to receive one versus two units was based on the number of stem cells contained in the UCB .

目的：探讨脐带血造血干细胞的体外扩增及移植最佳时机。

Objective : To explore the optimal time for expansion and transplantation of hematopoietic stem cell from umbilical cord blood in vitro .

脐带血干祖细胞移植在造血和免疫系统的恢复与重建中具有重要的临床应用前景。

Transplantation of stem / progenitor cells in cord blood shows great prospects in recovery and reconstitution of hematopoiesis and immune system .

目前，脐带血中干细胞移植仅能用于儿童因为脐带血不含有移植给成人所需的足够干细胞数量。

Currently , stem cell transplants with cord blood can only be used in children because cord blood does not contain enough stem cells for an amount needed to be transplanted into an adult .

该领域被广泛研究和关注的干细胞主要有胚胎干细胞、神经干细胞、骨髓基质干细胞和脐带血基质干细胞等。

In this field , the stem cells which are concerned and studied widely include embryonic stem cells 、 neural stem cells 、 bone marrow-derived mesenchymal stem cells and mesenchymal stem cells from umbilical cord blood and so on .

以脐带血造血干细胞库、人类辅助生殖技术、人类精子库等技术的管理问题为切入点，领导开展技术评估，以高质量证据制定卫生部的准入管理办法和条例。

Three technologies - Bank of Haematopoietic Stem Cell from Umbilical Cord , Assisted Reproductive Technology ( ART ) and Sperm Bank - were piloted to assess , which provided quality evidence to assist MOH in formulating the Regulation for Permission on Health Technology .

Endostatin基因导入人脐带血CD34+造血干细胞的实验研究

Human Endostatin Gene Transfered into CD34 + Hematopoietic Stem Cells from Human Umbilical Cord Blood

脐带血造血干祖细胞移植的基础

Basis for umbilical cord blood stem cell transplant

血管内皮抑素基因转染人脐带血CD34~+造血干细胞的实验研究

Transfection of human endostatin gene in umbilical cord CD34 ~ + hematopoietic stem cell