脑软化

结果（1）212例难治性癫痫患者中，118例MRI有改变，异常发现阳性率为55.7%（118/212），揭示的病因共7种，其中以脑软化、脑发育异常多见；

Results 1.In the 212 patients with refractory epilepsy , 118 had changes of MRI . Positive rate of abnormal findings was 55.7 % ( 118 / 212 ) . There were 7 kinds of diseases in which cerebromalacia and atelencephalia were most common .

脑软化切除治疗顽固性癫痫（150例报告）

Resection of Cerebromalacia for Intractable Epilepsy ( a Report of 150 Case )

1岁以后约20%病例有CT异常，表现为局限性脑软化灶和脑萎缩，并有相应的临床表现。

After one year , about 20 % cases had abnormal CT with localized cerebral softening and atrophy , and corresponding clinical manifestations .

MRI显示血肿12例，伴有脑软化、萎缩4例。

While hematoma were showed in 12 cases , encephalomalacia and brain atrophy were discovered in 4 cases with MRI .

两组患儿X线胸片检查均呈明显肺水肿表现，存活组患儿颅脑MRI检查均提示有脑干脑炎、脑软化灶改变。

The chest X-ray manifested pulmonary edema in both groups . Brainstem encephalitis and encephalomalacia were seen in cranial MRI detection of all survival group .

重度HIE在2个月内可引起脑软化和脑萎缩（80%）。

Severe degree HIE might cause cerebral malacia and atrophy ( 80 % ) in 2 months .

营养性脑软化症雏鸡血浆TXB2和6-keto-PGF（1α）含量变化的研究

The plasma level of TXB_2 and 6-keto-PGF_ ( 1 α) in chicken with nutritional encephalomalacia

体内自由基含量增加是雏鸡脑软化的启动因子，小脑中GSH-Px的耗竭是雏鸡脑软化的因素之一。

The increase of free radical in organism was the primer and the exhaustion of GSH-Px in cerebellum was one of the factors for chicken encephalomalacia . 3 .

5脑软化雏鸡血清中IgG、IgM、IgA含量及新城疫HI抗体效价极显著低于C组。

The concentration of serum IgG , IgM and IgA and the titre of hemagglutination inhibition antibody for Newcastle disease ( HI ) in ataxic chicks were significantly lower than that of the control group .

目的探讨发作间期及发作期单光子发射计算机断层扫描（SPECT）在脑软化灶导致癫疒间的伽玛刀治疗中的运用。

Objective To explore the application of inter ictal SPECT and ictal SPECT in Gamma-knife therapy epilepsy due to encephalomalacia . Methods 69 cases of epilepsy due to encephalomalacia underwent SPECT testing .

结论MSI对脑软化灶伴有难治性癫痫发作患者癫痫灶定位准确，具有指导临床进一步治疗的价值。

Conclusion The MSI localization of epileptic focus in patients with refractory epilepsy and encephalomalacia is precise , and it can direct the advanced clinical treatment .

首次采用SDS-PAGE电泳法分离并检测了雏鸡脑软化症神经细胞膜蛋白组分，并以高效薄层层析法检测神经细胞膜磷脂组分；

The protein and phospholipid constituent in membrane of neurocyte in brain of chicken with encephalomalacia was separated and studied with the method of SDS-PAGE electrophoresis and the method of high performance-thin layer chromatography respectively .

对脑软化灶导致癫疒间的患者行SPECT检查，只有发作间期放射性分布减低和发作期增高在同一脑区才被确认为致疒间灶；

Focal seizure patients have best curative effect . Epilepsy due to encephalomalacia perform SPECT , only the brain areas that distributing of radioactivity diminution in inter ictal SPECT , in the same time , distributing of radioactivity heighten in ictal SPECT should be sure of epilepsy focus .

人人都在捉摸你的脑软化症状。

Everybody is looking for symptoms of softening of the brain .

磁源性影像对脑软化灶伴发难治性癫痫的定位价值

Manifestation of magnetic source imaging in patients with refractory epilepsy and encephalomalacia

雏鸡脑软化症免疫组织的氧化和抗氧化特性

The Oxidative and Anti-oxidative Characteristics of Immune Tissues in Chicken with Encephalomalacia

这种脑软化结果会导致疯颠。

This softening of the brain would end in madness .

目的探讨脑软化灶相关癫的手术治疗方案和效果。

Objective To probe surgical methods and their curative effect of epilepsy associated with encephalomalacia .

脑软化（492%）；

Brain malacia ( 49 2 % );

皮层脑电图监测下多种术式联合治疗脑软化灶所致的继发性癫痫

Management of combined multiform operations for epilepsy caused by encephalomalacia under the monitoring of electrocorticography

雏鸡脑软化症的分子机理

The Molecular Mechanism of Chicken Encephalomalacia

右额叶脑软化额极大部分被旧梗塞灶液化坏死后留下的高信号脑脊液替代。

Right frontal encephalomalacia The frontal pole is largely replaced with the high signal of cerebrospinal fluid left after liquifaction necrosis in this old infarct .

铁离子价态的变化表明铁在自由基的产生过程中起介导作用，对雏鸡脑软化症的发生起促进作用。

The change of Fe ion status showed that Fe acted as medium in the progress of synthesizing free radical . It promoted the occurrence of chicken encephalomalacia .

脑软化雏鸡体内铁、铜含量增高，锌含量降低，硒含量的变化与GSG-Px活性的变化相一致，而钙、钴、锰的含量没有变化。

The content of Fe and Cu increased and the content of Zn decreased , the change of the content of Se was consistent with the change of activity of GSH-Px and the content of Ca and Co did not changed in chicken with encephalomalacia .

142例存活，其中125例随访6月至3年，48例有脑软化灶，其中10例与同侧脑室相通，5例确诊为外伤性癫痫。10例死亡，病死率6.58%。

Ten of them were dead and the mortality rate was 6.58 % . Follow up of 125 cases ranged 6 months to 3 years , and it was found 48 cases were with cerebral softening , 10 of whom had communicated ventricles of brain and 5 had tramatic epilepsy .

治疗组血肿吸收快，复查脑CT无软化灶，无穿透性损伤，生存率明显提高，致残率明显降低。

Moreover , in treatment group , the absorption of hematoma was rapider , CT reexamine was no found soften lesion , there was no penetrating injury in brain , the survival rate was raised and disability rate was decreased obviously .

结论：慢性酒精中毒性脑病、肝病的CT表现特点是不同程度的脑萎缩、脑软化灶、脂肪肝、肝硬化。

Conclusion : The CT appearances of chronic alcoholic toxic cerebral injuries and liver injuries were cerebral atrophy in different degree , encephalomalacia foci , fatty liver , liver cirrhosis .

bFGF治疗可降低脑萎缩、脑软化的发生率（310%、241%）（P<005）。

The treatment with bFGF could greatly relieve the cerebral injury of HI , and reduce the incidences of brain atrophy and malacia to 31 0 % and 24.1 % , respectively ( P < 0.05 ) .

结果200例患儿中，32例CT正常（16%），168例异常（84%），包括脑萎缩、脑软化、脑室周围白质软化（PVL）、小脑发育不良、脑畸形等。

Results 200 cases had brain CT scanning , of which 32 were normal ( 16 % ), while 168 had abnormal findings ( 84 % ), including atrophy of brain , encephalomalacia , PVL , cerebellum atrophy , deformity of brain .

头颅CT或磁共振成像显示脑发育不良、脑软化、脑白质异常信号，脑电图显示慢波或样活动。

Head CT or magnetic resonance imaging revealed brain dysplasia , encephalomalacia and abnormal white matter signal , and electroencephalography displayed slow wave or epileptiform activity .