脱羧反应

在脱羧反应中，反应温度220℃，反应时间2h。

And the reaction temperature is 220 ℃, the reaction time is 2 h for the reaction of decarboxylation .

脱羧反应温度为280℃，反应时间0.5h；

Decarboxylation reaction temperature 280 ℃, reaction time 0.5 h ;

脱羧反应以三乙醇胺代替剧毒的N，N－二甲基苯胺，并对其后处理进行了改进。

Triethanolamine was used instead of N , N-dimethylaniline in decarboxylation .

以丁二酮为主要原料，经缩合、脱羧反应，以62.3%的总收率合成了2,5-二甲基-3（2H）-呋喃酮。

Dimethyl-3 ( 2H ) - Furanone is synthesized using biacetyl as basic material . by means of condensation and decarboxylation with the total yield amounting to 62.3 % .

此外，通过Perkin反应合成了4种芳基取代丙烯酸，研究了其关环和脱羧反应。

In addition , some aryl-substituted propenoic acids were prepared via Perkin reaction . The cyclization and decarboxylation reaction were studied .

2-酮基-D-葡萄糖酸加热脱羧反应的研究

Study on the Decarboxylation of 2 - Keto - gluconic Acid

苯甲酸脱羧反应过程的拉曼光谱研究

Research on Raman Spectra of Benzoic Acid during Decarboxylic Process

脱羧酶酶的一种，可水解羧基酸芳香羧酸进行脱羧反应是一个例外。

One exception is the decarboxylation of aromatic carboxylic acids .

目的：研究喹诺酮类化合物脱羧反应。

Aim : To study the decarboxylation of quinolones .

丙二酸发生羟醛缩合时的二次脱羧反应

The second decarboxylation of malonic acid in aldol condensation

脱羧反应研究进展

Progress in The Study of The Decarboxylation Reaction

喹诺酮类化合物3-脱羧反应研究

The Study of 3-decarboxylation of Quinolones

脱羧反应的历程及其应用

Mechanism and Application of Decarboxylation

3氯2硝基苯基乙酸通过脱羧反应得到最终产品3氯2硝基甲苯，产率为72.9%。

Decarboxylation reaction of 3 chloro 2 nitrophenylacetic acid produced 3 chloro 2 nitrotoluene in 72.9 % yield .

结论：为新型喹诺酮类化合物的合成研究和3-脱羧反应的研究提供参考。

Conclusion : the reference to the study of decarboxylation for the synthesis of novel quinolones was offered .

第一章：在第一章中，系统的总结了各类脱羧反应的发展和在有机合成中的应用。

Chapter 1.In chapter 1 , development and application of decarboxylation reactions in organic synthesis were summarized in detail .

水合质子进攻羧基的α-C有利于阴离子形式发生脱羧反应。

Decarboxylation of the anion form is favorable to occur via a hydrated proton attacking the a-C site of the carboxyl group .

氟离子流失速率随着脱羧反应温度的升高而减小，意味着聚合物侧链的开裂更少。

The fluoride emission rate increasing ratio decreased with the increased decarboxylation temperature , implying the low side chain cleavage of the polymer .

水解脱羧反应：β-酮酸酯在酸性条件下水解生成β-酮酸，β-酮酸脱羧，即得产品2-甲氧基-4'-三氟甲基苯乙酮。

Hydrolysis and decarboxylation reaction : In acid condition , the β - carbonyl carboxylic ester was hydrolyzed to give β - carbonyl carboxylic acid , and the β - carbonyl carboxylic acid was decarboxylated to give 2-methoxy-4 ' - trifluoromethyl acetophenone .

因此，我们发展了一种非常高效的铜催化的卤代烃与炔酸的脱羧偶联反应。

Therefore , we developed a highly efficient copper-catalyzed decarboxylation-coupling reaction between halides and alkyne acids .

本论文以苯乙酮和氯乙酸乙酯为原料，经Darzens缩合、酯基水解、脱羧、氧化反应过程合成了2-苯基丙酸，全合成产率为63.4%，对其工艺过程进行了研究和优化。

In this dissertation , the 2-phenylpropionic acid was synthesized in a total yield of 63.4 % by Darzens condensation , hydrolysis of ester , decarboxylation and oxidation with acetophenone and ethyl chloroacetate as starting materials .

方法：在喹诺酮类化合物5与邻苯二胺缩合中，以PPA为脱水剂，可以得到3-脱羧反应的产物。

Methods : By condensing compound 5 with o-phenylenediamine , 3-decarboxylic quinolones can be obtained .