起始因子

另外，HIF-1能激活血管内皮生长因子（VEGF）基因的转录活性，因而HIF-1被认为是肿瘤血管生成的重要起始因子。

In addition , by activating transcription of the vascular endothelial growth factor ( VEGF ) gene , HIF-1 α is considered to be a central initiator of angiogenic activity in tumors .

蛋白翻译起始因子C2在原发性肝细胞肝癌中表达的意义

Significance of translation initiation factor C_2 expression in hepatocellular carcinoma tissues

日本血吸虫真核生物翻译起始因子2α亚基全长cDNA的克隆与功能分析

Cloning and function analysis of full-length cDNA sequence of Schistosoma japonicum eukaryotic translation initiation factor 2 alpha subunit

蛋白翻译起始因子C2在结、直肠癌中表达的意义

Expression significance of translation initiation factor C2 gene in colorectal cancer tissue

蛋白翻译起始因子C2在消化道肿瘤中的表达和意义

The Expression and Significance of Protein Translation Initiation Factors C2 in Digestive System Neoplasms

C2基因是在肝癌研究过程中克隆出的人源性真核细胞蛋白翻译起始因子。

C2 gene is a new cloned human eukaryotic translation factor during the study of hepatic carcinoma .

真核生物翻译起始因子5A的结构与功能研究进展

Structure and function of eukaryotic initiation factor 5A : recent progress in research

蛋白翻译起始因子C2在肝癌、胃癌中的表达与分布

The expression and distribution of protein translation initiation factors C2 gene in hepatocellular carcinoma and gastric cancer tissue

而信号转导、转录因子、激素及核糖体蛋白、转录起始因子等相关基因的mRNA与蛋白质丰度差异显著。

While mRNA and protein expression abundant of the genes that are related to signal transduction , transcription factor , hormone , ribosomal protein and translation initiation factor is significantly different .

真核细胞翻译起始因子4E在子宫内膜癌中的表达及意义

Eukaryotic Translation Initiation Factor 4e Expression in Endometrioid Adenocarcinoma and Its Significance

1个基因与翻译起始因子eIF成员有高的同源性。

One gene is highly homologous to the translation initiation factor eIF .

他们的实验证明，AD脑部存在由于GA缺失造成移码突变的β淀粉样蛋白前体和泛素－B，并推测这种移码突变是AD病理的重要起始因子。

They proved mutants of β - amyloid precursor protein and ubiquitin-B , caused by GA deletion and subsequent frameshift mutation , existed in AD brain and surmised that transcript mutation was a critical factor for initiating neuropathology in nonfamilial AD.

真核细胞转录起始因子4E表达与乳腺癌血管生成及淋巴结转移的关系

Relationship among expression of eukaryotic initiation factor 4E , tumor angiogenesis and lymph node metastasis in breast cancer

真核细胞翻译起始因子4E及基质金属蛋白酶-9在声门上喉癌和下咽癌转移淋巴结中的表达

Expression and clinical value of eukaryotic initiation factor 4E and matrix metalloproteinase-9 in supraglottic and hypopharyngeal carcinoma and metastasic lymph

一般说来，蛋白激酶R（PKR）介导的磷酸化反应和翻译起始因子eIF-2α的失活，导致蛋白翻译的抑制，细胞凋亡。

Generally , protein kinase R ( PKR ) mediated phosphating reaction and dysfunction of initiation factor eIF-2 α resulted in inhibition of protein translation and cell apoptosis .

真核生物的翻译起始因子5A（eIF5A）是调控生物生长发育、衰老及环境适应等的重要因子。

Eukaryotic translation initiation factor 5A ( eIF5A ) is involved in cell proliferation , senescence , development and environmental response .

在健康的哺乳动物细胞中，Bax主要在细胞质中，但是作为细胞凋亡的起始因子，它会改变构象而插入细胞器的膜上，主要在线粒体的膜上。

In healthy mammalian cells , the majority of Bax is found in the cytosol , but upon initiation of apoptotic signaling , Bax undergoes a conformation shift , and inserts into organelle membranes , primarily the outer mitochondrial membrane .

真核起始因子5A（eIF-5A）普遍存在于所有真核细胞内，是目前发现唯一一个含有hypusine残基的蛋白质。

The eukaryotic initiation factor 5A ( eIF-5A ) is one of the most abundant initiation factors in the eukaryote , and it is the only protein in nature that contains a hypusine residue .

真核生物起始因子5（eIF5）是一种重要的翻译起始因子，过去人们认为它只是GTP酶活化因子，催化eIF2上的GTP水解，促进80S起始复合体的形成。

Eukaryotic initiation factor 5 ( eIF-5 ) is an important factor in translation initiation . It acts as a GTPase activating factor to mediate the hydrolysis of GTP binding to eIF-2 which is essential for the composition of functional 80S complex .

红藻氨酸致痫大鼠海马神经元中真核生物起始因子2α酶切片段的产生

Cleavage of eIF2 α in hippocampal neurons of kainic acid epileptic model rat

真核翻译起始因子与肿瘤

Eukaryotic Translation Initiation Factors and Tumor

真核细胞翻译起始因子-4E；

Eukaryotic cell translation initiation-eIF4E gene ;

如严重的动脉低血压和休克为起始因子，恢复充足的血压至关重要。

If severe arterial hypotension and shock are initiating factors , restoration of adequate BP is essential .

真核生物起始因子5

Eukaryotic Initiation Factor 5

另外有大量伸长因子、转录因子、真核起始因子和应激蛋白差异表达。

Also , many elongation factors , transcript factors , eukaryotic initial factors and stress proteins were differentially expressed .

统计结果显示，贮藏蛋白以及相应的核糖体蛋白，起始因子，延伸因子以及转录因子等基因高丰度表达。

Of them , most highly-expressed genes encoded storage proteins , starch , ribosome proteins , initiation factors , elongation factors and transcription factors .

因此，胰腺缺血是坏死性胰腺炎的持续损害因子，既是起始因子，又是恶化因子，且不可能出现再灌注损伤现象。

We conclude that pancreatic ischemia is a continous injury factor in ANP , and there is no reperfusion injury in the course of the disease .

斑节对虾真核生物翻译起始因子3亚基4（btseIF3g）序列分析及组织表达特性

Sequence analysis of eukaryotic translation initiation factor 3 subunit G ( eIF3g ) of black tiger shrimp ( Penaeus monodon ) and its mRNA tissue expression

异常的翻译调控可以导致细胞的恶性转化以及翻译起始因子和信号传导通路的改变。

Aberrant control of translation could result in cell transformation , and changes in the expression of key initiation factors or the signaling pathways that regulated them were often observed in tumors .

Toll样受体，作为重要的模式识别受体，能通过识别不同的病原微生物，活化特异的信号通路，起始细胞因子的表达。

Toll-like receptors , serve as pattern recognition receptors ( PRRs ), activate specific signaling pathways that initiate the production of cytokines through recognizing different microbial components .