运动性哮喘

目的观察孟鲁司特钠治疗轻、中度支气管哮喘（简称哮喘）并发运动诱发支气管收缩（EIB）或运动性哮喘（EIA）的治疗及预防作用。

Objective To study the efficacy of montelukast , a cysteinyl leukotriene receptor antagonist , in the treatment and prevention of exercise-induced bronchoconstriction ( EIB ) in mild asthmatic patients and patients with exercise-induced asthma ( EIA ) .

目的通过内皮素（ET）受体非肽类拮抗剂Bosentan对豚鼠等CO2过度通气模型影响的观察，探讨运动性哮喘的发病机制以及ET受体拮抗剂的治疗作用。

Objective To investigate the effects of endothelin antagonist , Bosentan on bronchoconstriction elicited by isocapnic hyperpnea in guinea pigs and to explore the effect of endothelin in the pathogenesis of exercise induced asthma ( E1A ) .

结论扎鲁司特对儿童运动性哮喘有较好的治疗作用。

Conclusion Zafirlukast has definite treating effect on exercise-induced bronchoconstriction in children .

脂多糖和甲双吡丙酮诱发形成豚鼠运动性哮喘模型

A model for exercise induced asthma in guinea pigs with lipopolysaccharide and metyrapone

结论在用脂多糖和甲吡丙酮预处理的运动性哮喘豚鼠模型中，氯雷他定和酮替芬能够抑制支气管收缩。

Conclusion Loratadine and ketotifen can inhibit the exercise-induced bronchoconstriction in guinea pigs pretreated with LPS and metyrapone .

目的研究白三烯受体拮抗剂-扎鲁司特对运动性哮喘的治疗作用。

Objective Zafirlukast , leukotriene receptor antagonist , is introduced in this study to investigate its effect on exercise induced bronchospasm .

作为一种半胱氨酰白三烯受体拮抗剂，孟鲁司特是阿司匹林过敏性哮喘和运动性哮喘的治疗的一线选择。

Montelukast , as a cysteinyl leukotriene receptor antagonist , is one of the first-line drugs of asthma treatment , is generally considered to have a niche application in the therapy of exercise and aspirin induced asthma .

结果运动性非外伤性疾病主要有运动性晕厥、哮喘、血尿、胃肠痉挛、低血糖、荨麻疹、中署、猝死等。

Results The motive and traumatic disease mainly includes motive syncope 、 asthma 、 haematuria 、 gastrospasm 、 hypoglycemia 、 urticaria 、 heatstroke 、 sudden death and so on .