造血生长因子

人参皂甙对K562细胞表面分化抗原及造血生长因子受体表达的影响

Effect of total saponins of Panax ginseng on K562 cells in expressing clusters of differentiation antigen and hematopoietic growth factor recepters

结果通过给予保护性隔离、强有力的抗菌药物、造血生长因子以及积极的支持治疗等措施，使14例（93.33%）患者救治成功，发热症状在3～11d得到控制。

Results Fourteen patients ( 93.33 % ) were brought out of danger after receiving protective isolation , effective antimicrobial agents , hematopoietic growth factor and active supportive treatment , fever was controlled within 3-11 days .

促红细胞生成素（EPO）是分子量为34.4kD的糖蛋白，也是机体重要的造血生长因子。

Erythropoietin ( EPO ), a 34.4 kD glycoprotein hormone , is an important hematopoiesis factor .

Egr-1启动子序列调控造血生长因子表达的实验研究

Study of the expression of hematopoietic growth factors regulated with Egr-1 promotor sequence

目的：研究血小板生成素（TPO）及其他造血生长因子在体外对人血小板活化的影响。

AIM : To study the effects of thrombopoietin ( TPO ) and other hematopoietic cytokines on platelet activation .

该结果显示，人巨核细胞增殖受多种造血生长因子调控，其中TPO是特异地调控人巨核祖细胞生长的一种细胞因子。

The results suggested that megakaryocytopoiesis was regulated by several cytokines and that TPO was a megakaryocytic lineage specific cytokine .

体外培养的人AGM区基质细胞表达多种造血生长因子

Hematopoietic Growth Factors Expressed in Human Aorta-Gonad - Mesonephros ( AGM ) - Derived Stromal Cells in vitro

目前，利用基因工程重组技术制备的重组造血生长因子已成为促进ARS造血功能恢复治疗中的首选药物。

At present , recombinant hematopoietic growth factors synthesized through gene engineering recombination technology are the choice drug to promote hematopoietic recovery in ARS treatments .

血小板生成素（thrombopoietin，TPO）是近几年发现的一种造血生长因子，其功能是促进巨核细胞的发育成熟，调节血液中血小板的水平。

Thrombopoietin is a newly found hemopoietic growth factor that stimulates the development and maturation of megakaryocytes and thus regulates the platelet level in the blood .

背景：Flt3基因是近年来发现的早期造血生长因子受体基因。

BACKGROUND : Fms-like tyrosine kinase-3 ( FLT3 ) gene is one of the receptors for growth factors in early hematogenesis .

G-CSF是一种重要的造血生长因子，对人体外周血粒细胞数量和功能维持起着十分关键作用。

Granulocyte colony-stimulating factor ( G-CSF ) is one of important haemopoietic growth factors , and it plays an important part in sustaining the counts and functions of granulocyte for people .

其中，SCF不同于其他造血生长因子，它是作用于较早期的造血干细胞或原始造血祖细胞，促进这些细胞的存活、增殖和分化。

Among them , SCF is different , which can act directly on early hematopoietic stem cells and primitive hematopoietic progenitor cells and induce the survival , proliferation and differentiation of these cells .

结论TSPG协同造血生长因子能促进CD34+细胞定向诱导分化为粒系血细胞。

Conclusion TSPG may promote CD34 + cells to proliferate and differentiate to granulocytopoietic lineage by synergism with hematopoietic growth factors .

探讨造血生长因子GM-CSF／IL-3融合蛋白、GM-CSF及IL-3抗γ射线辐射诱导Tf-1细胞凋亡的分子机制。

To investigate the molecular mechanisms of the anti-apoptosis effects of hematopoietic growth factors GM-CSF / IL-3 fusion protein , GM-CSF and IL-3 in Tf-1 cells induced by γ - irradiation .

造血生长因子，尤其是促红细胞生长素（EPO）。在促进红系祖细胞的增殖，防止细胞凋亡、激活特异基因表达等方面起着重要的作用。

Hematopoietic growth factors , especially erythropoietin ( EPO ), play important roles in promotion of the survival , proliferation and differentiation of erythroid progenitor cells , and in the activation of expression of specific genes in the cells .

造血生长因子与受体结合后激活JAK，JAK发生自我磷酸化的同时也使受体磷酸化，继而通过SH2蛋白激活ras通路。

The JAKs are associated with the receptors and activated following ligand binding . The activated JAKs phosphorylate both themselves and the receptor subunits , and through SH2-containing proteins activate the ras pathway .

结论TPO等造血生长因子可能主要通过GPCRs-Ras-MAPK途径，促进脐血干细胞向巨核细胞系增殖、分化。

Conclusion TPO and some other hematopoietic growth factors may enhance the proliferation and differentiation of megakaryocytes derived from stem cells in cord blood by GPCRs-Ras-MAPK pathway .

粒细胞集落刺激因子（G-CSF）是最重要的造血生长因子之一，最新的研究成果表明其对获得性免疫和T细胞耐受有十分重要的作用，但机制尚未阐明。

Recently , granulocyte colony-stimulating factor ( G-CSF ) which is an important hematopoietic growth factor of the myeloid lineage was shown a profound immunoregulatory effects in adoptive immunity and T cell tolerance . But the mechanism is still not very clear .

造血生长因子对急性髓系白血病细胞动力学耐药的克服英文

Overcoming Cytokinetic Resistance of Acute Myeloid Leukemia with Hematopoietic Growth Factors

造血生长因子受体对急性髓性白血病细胞增殖的调控作用

Effects of hematopoietic growth factor receptors on proliferation of AML cells

5种造血生长因子对造血祖细胞集落形成的影响

Effects of Five Hematopoietic Growth Factors on Colony Formation of Hematopoietic Progenitor Cells

联合应用四种造血生长因子对不同骨髓细胞集落形成的作用

Effect of Four Recombinant Hematopoietic Growth Factors on Colony-Forming of Various Marrow Cells

血液恶性肿瘤的支持疗法：造血生长因子、输血及抗感染治疗

Supportive care in hematological malignancies : hematopoietic growth factors , infections , transfusion therapy

造血生长因子在肿瘤化疗中应用的研究进展

Application of hematopoietic growth factors in malignancy chemotherapy

高压氧联合造血生长因子能够更加有效地动员外周血造血干细胞。

HBO combined with hematopoietic growth factors could mobilize peripheral blood stem cells more efficiently .

人干细胞因子与其它造血生长因子对造血集落形成的协同作用

Synergic effects of rhSCF and other hematopoietic growth factors on hematopoietic colony formation in vitro

儿茶素对骨髓细胞周期及造血生长因子基因表达的作用

Effect of catechin on bone marrow cell cycle and gene expression of hematopoietic growth factors

四种造血生长因子对小鼠骨髓巨核系祖细胞集落体外形成的影响

In vitro effect of four kinds of hematopoietic growth factors on the formation of murine CFU-MK

序贯强化免疫抑制并用造血生长因子治疗重型再生障碍性贫血

Sequential intensified immunosuppressive therapy combining with hematopoietic growth factors in the treatment of severe aplastic anemia

目的：探索大剂量照射后造血生长因子受体基因的表达规律。

Objective : To investigate the expression level of some hematopoietic growth factor receptors after large_dose irradiation .