铂化合物
- 网络platinum compounds;Cisplatin
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铂化合物是广泛应用的抗癌药物。
Platinum compounds are widely used anticancer drugs .
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目前还有另外9种铂化合物仍在进行临床研究,这些化合物为顺铂和卡铂的类似物、亲脂性配合物、口服铂(Ⅳ)配合物、多核铂配合物以及具有空间位阻的铂配合物。
Another 9 platinum compounds are being still clinically tested worldwide . These include the analogues of Cisplatin and Carboplatin , the lipophilic complexes , the oral Pt (ⅳ) complexes , the multinuclear complexes and the sterically hindered complex .
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2,2′-双吡啶双氯二价铂化合物Pt(bpy)Cl2(黄色)的电子结构和电子光谱性质的从头计算研究
Ab initio study on the electronic structure and electronic spectrums of yellow Pt ( bpy ) Cl_2
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初步尝试了阳离子钳形铂化合物在反式硝基苯乙烯和吲哚的不对称傅克烷基化反应中的应用,最高取得了80%的收率和60%的ee值。
The cationic pincer platinum complexes were applied to the asymmetric Friedel-Crafts alkylation of indole with trans - β - nitrostyrene , affording the product with up to80 % yield and60 % ee .
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结果表明,这种筛选出来的铂化合物完全可以取代H2PtCl6作为一种新型的铂前驱体。
It is claimed that the chosen platinum compound can substitute for H_2PtCl_6 as a new precursor .
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本组实验结果提示,在肝门部胆管癌的化疗中,蒽环类、铂化合物类抗肿瘤药可能是较为有效的。
According to our result anthracycline antibiotic and platinum compound are more effective than others for the treatment of human hilar cholangiocarcinoma .
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回顾铂类化合物的发展历程及临床评价
Reviewing the Course of Development of the Compatibility of Platinum in Retrospect and Clinical Evaluation
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微波消解技术在难溶贵金属(铂)化合物分析中的应用
Application of Microwave-assisted Digestion Technique for Platinum Analysis in Difficultly Decomposed Compounds of Precious Metals
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因此,目前医学界一方面寻找新的高效低毒铂类化合物,一方面寻找能对顺铂所致肾毒性有保护作用但又不抑制其抗肿瘤效应的新的化合物。
At present , new complex of platinum has been studied , on the other hand , new protective agents which can reduce the nephrotoxicity of cisplatin and keep the antineoplastic effects have been investigated as well .
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结果和结论:近30年来,铂类化合物的临床研究进展迅速,其抗肿瘤谱广,抗癌活性增强,不良反应降低。
RESULTS & CONCLUSION : Advance in clinical research on the compatibility of platinum has been swift in recent 30 years . It has a broad antitumor spectrum , stronger anticarcinogenic activity , especially lower drug adverse reaction .
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含二元胺或氨基酸酯的铂配位化合物的合成及抗癌活性
Synthesis and antitumor evaluation of some platinum coordination compounds containing diamine or amino-acid ester
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非铂类金属抗癌化合物的研究进展
Investigation of anticancer active non-platinum-group metal compounds
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本文以炭纤维布为载体制备了质子交换膜燃料电池负载型催化剂,通过在贵金属铂中添加稀土元素铈的氧化物方式促使铂铈化合物的形成,改良了催化剂的氧化还原的性能。
In this paper , carbon fiber cloth as the carrier prepared by proton exchange membrane fuel cell supported catalysts , precious metals platinum by adding rare-earth element cerium oxide cerium compounds ways to promote the formation of platinum , improved redox catalyst performance .
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樟脑胺氯乙酸铂(camphoraminechloroaceticplatinum,CCP)是一新的抗癌铂类化合物。
Camphoramine Chloroacetic Platinum ( CCP ) is a new anticancer platinum complex .