侵蚀性葡萄胎

葡萄胎、侵蚀性葡萄胎、绒癌的发生发展可能与PTEN无关。

Hydatidiform mole , invasive mole and choriocarcinoma may be irrelevant to PTEN .

目的：妊娠滋养细胞疾病（gestationaltrophoblasticdisease，GTD）是一组来源于胎盘绒毛滋养细胞的疾病，包括葡萄胎、侵蚀性葡萄胎、绒毛膜癌和胎盘部位滋养细胞肿瘤。

Objective : Gestational trophoblastic disease ( GTD ) is a group of diseases from placental trophoblast cells , including hydatidiform mole , invasive mole , choriocarcinoma and placental site trophoblastic tumor .

侵蚀性葡萄胎ER及β-HCG表达对预后影响的研究

The relationship between prognosis and expression of ER and β - hcg in invasive moles

ras基因突变与侵蚀性葡萄胎组织分化的关系研究

Relationship Between the ras Gene Mutation and Tissue Differentiation in the Invasive Hydatidiform Mole

目的：探讨侵蚀性葡萄胎、绒癌肺转移灶的发生、发展、消退与血HCG值之间的相关性，了解其变化规律，指导临床治疗。

Objective : By exploring the relationship between the occurrence , development and serum HCG to know its change regularity and guide clinical treatment .

结论：CDFI对侵蚀性葡萄胎的诊断以及观察其疗效是一个非常有价值的方法。

Conclusion : CDFI is a useful method in the diagnosis of invasive hydatidiform mole and in monitoring the tumor response to chemotherapy .

葡萄胎中c-myc和ras癌基因表达及其意义良性与侵蚀性葡萄胎的预测及临床应用

The expression of c-myc and ras oncogenes in hydatidiform moles and it 's significance Prediction of benign and invasive hydatidiform moles and its practical value

侵蚀性葡萄胎中化疗组MMP-2阳性表达率明显低于未化疗组（P<0.05）；

The positive rates of MMP-2 expression in invasive hydatidiform mole groups with chemotherapy were significantly lower than those without chemotherapy ( P < 0.05 ) .

本文应用免疫组织化学PAP法对40例侵蚀性葡萄胎雌激素受体（ER）及绒毛膜促性腺激素β-亚单位（β-HCG）进行研究。

The localization of estrogen recepter ( ER ) and human chorionic gonadotropin (β - HCG ) in 40 invasive moles were carred out by using immunohistochemical PAP methods .

术后HCG持续上升且影像学检查示肺转移，诊断为侵蚀性葡萄胎，由产科转入妇科进行治疗。

The HCG increased continuously and Imaging examination showed pulmonary metastasis after operation and the diagnosis was Invasive mole . The patient was transferred from obstetric department to gynecology for treatment .

为了探讨非侵蚀性葡萄胎（HM）转化为侵蚀性葡萄胎（IHM）的细胞生物学机制，本研究采用免疫组织化学法观察了NGF和TGF－β1在HM和IHM中的分布。

In order to study the regulating mechanism of NGF and TGF - β 1 in HM and IHM , ABC immunohistochemistry method was used .

在葡萄胎（HM）、侵蚀性葡萄胎（IM）及绒毛膜癌（CC）中E-cad的正常表达率分别为53.3%、31.25%和16.67%；

In HM ( hydatidiform mole ), IM ( invasive mode ) and CC ( choriocarcinoma ), the normal expression rates of E-cad were 53.3 % , 31.25 % and 16.67 % , respectively ;

结果在葡萄胎、侵蚀性葡萄胎中E-cad的正常表达率分别为53.3%，31.25%；

Results In HM ( hydatidiform mole ) and IM ( invasive mole ), the normal expression rates of E-cad were 53.3 % , 31.25 % respectively ;

HLA-G蛋白在早孕绒毛、葡萄胎和侵蚀性葡萄胎中表达依次增强，三者比较，差异非常显著（P<0.001）。

The expression of HLA-G protein increased in the order of normal villus , hydatidiform mole and invasive hydatidiform mole , there were significant differences among them ( P < 0.001 ) .

以肌壁血窦＞5mm作为侵蚀性葡萄胎的诊断标准，其敏感性95%，特异性100%。

That the size of blood sinusoid was more than 5 mm was used as the criterion for diagnosis of the invasive mole . the sensitivity rate was 95 % and specificity rate was 100 % .

妊娠滋养细胞疾病（GTD）包括葡萄胎、侵蚀性葡萄胎、绒毛膜癌等一系列与妊娠相关的疾病谱，目前为止确切的发病机制仍不清。

Gestational trophoblastic diseases ( GTD ) include the abnormal pregnancy , hydatidiform mole ( HM ), invasive mole , the overtly malignant tumors , choriocarcinoma and placental site trophoblastic tumor . The molecular pathogenesis of GTD remained largely unknown .

158例侵蚀性葡萄胎发病时间统计分析

The attack period of invasive mole : statistical analysis of 158 cases

彩色多普勒血流显像在侵蚀性葡萄胎的应用价值

Study of the clinical application of color Doppler imaging in invasive hydatidiform mole

结果侵蚀性葡萄胎28例，绒毛膜癌10例。

Results 28 cases were from invasive mole , and 10 cases were from choriocarcinoma .

1例侵蚀性葡萄胎子宫穿孔继发弥漫性腹膜炎患者的术后护理

Postoperative Nursing on One Patient with Diffuse Peritonitis Complicated with Erodent Hydatidiform Mole and Perforation of Uterus

目的：建立人侵蚀性葡萄胎裸鼠皮下移植瘤模型，探讨其生物学特性。

Objective : To establish subcutaneous transplanted model of human invasive mole in nude mice and to explore their biological properties .

结果提示绒癌和侵蚀性葡萄胎的β-HCG半定量测定是可信的。

The results showed that the β - HCG of semi - quantitative assay in choriocarcinoma and invasive mole was feasible and reliable .

侵蚀性葡萄胎均表现为蜂窝状回声，肌壁间病灶内可见丰富的低阻血流信号。

Invasive mole : all cases showed honey combed patterns , and the abundant colored flows of low resistance could be shown in the lesions .

目的：妊娠滋养细胞疾病包括葡萄胎、侵蚀性葡萄胎、绒毛膜癌（简称绒癌）及胎盘部位滋养细胞肿瘤。

Objective : Gestational trophoblastic diseases ( GTD ), included hydatidiform mole , invasive mole , choriocarcinoma and placental site trophoblastic tumor ( PSTT ) .

绒癌和侵蚀性葡萄胎中，滋养细胞内β-HCG含量与其滋养细胞增生程度呈正相关。

( 4 ) The β - HCG content of trophoblast in choriocarcinoma and invasive mole was positively correlated with the degree of trophoblastic proliferation .

侵蚀性葡萄胎增生型的β-HCG含量高于退变型（P<0.002）。

( 3 ) In invasive mole , the degenerative type had lower β - HCG content as compared with the proliferative type ( P < 0 . 002 ) .

绒癌两种滋养细胞的β-HCG含量高于侵蚀性葡萄胎、葡萄胎和正常绒毛（P<0.001）。

( 2 ) The β - HCG content of trophoblasts of choriocarcinoma was higher than that of the invasive moles and normal placental tissues ( P < 0.001 ) .

方法分析绒癌和侵蚀性葡萄胎患者化疗后在1年内妊娠的22例发生异常妊娠、废胎率的情况及其与化疗停药的间隔的关系。

Methods 22 patients conceived within one year after chemotherapy were followed up and analysed about abnormal pregnant result , wastage rate and the time of interval between chemotherapy and pregnancy .

方法自1990年2月至2001年6月，因瘤灶大出血而行超选择性动脉栓塞术治疗的恶性滋养细胞肿瘤患者31例，其中绒毛膜癌患者24例，侵蚀性葡萄胎7例。

Methods From February 1990 to June 2001 , 31 patients ( choriocarcinoma 24 , invasive mole 7 ) with hemorrhage from malignant gestational trophoblastic tumor were treated with superselective arterial embolization .

结果：绒癌和侵蚀性葡萄胎阴道转移的发生率分别为8.6%和4.1%，转移灶多位于阴道前壁下段。

Results : The incidences of vaginal metastasis in choriocarcinoma and invasive mole were 8.6 % and 4.1 % , respectively . The metastatic tumors were mostly located in the anterior wall of the lower part of vagina .